Journal of Biomedical Engineering Research (대한의용생체공학회:의공학회지)

The Korean Society of Medical and Biological Engineering (대한의용생체공학회)
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Development of a Real-time Medical Imaging System Combined with Laser Speckle Contrast Imaging and Fluorescence Imaging

형광과 레이저 스펙클 대조도 이미징을 결합한 실시간 의료영상 시스템 개발

  • Shim, Min Jae (Department of Biomedical Engineering, Pukyong National University) ;
  • Kim, Yikeun (Department of Research and Development) ;
  • Ko, Taek Yong (Kosin University Gospel Hospital) ;
  • Choi, Jin Hyuk (Kosin University Gospel Hospital) ;
  • Ahn, Yeh-Chan (Department of Biomedical Engineering, Pukyong National University)
  • Received : 2021.06.17
  • Accepted : 2021.06.23
  • Published : 2021.06.30
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Abstract

It is important to differentiate between the target tissue (or organ) and the rest of the tissue before incision during surgery. And when it is necessary to preserve the differentiated tissues, the blood vessels connected to the tissue must be preserved together. Various non-invasive medical imaging methods have been developed for this purpose. We aimed to develop a medical imaging system that can simultaneously apply fluorescence imaging using indocyanine green (ICG) and laser speckle contrast imaging (LSCI) using laser speckle patterns. We designed to collect images directed to the two cameras on a co-axial optical path and to compensate equal optical path length for two optical designs. The light source used for fluorescence and LSCI the same 785 nm wavelength. This system outputs real-time images and is designed to intuitively distinguish target tissues or blood vessels. This system outputs LSCI images up to 37 fps through parallel processing. Fluorescence for ICG and blood flow in animal models were observed throughout the experiment.

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Acknowledgement

이 논문은 부경대학교 자율창의학술연구비(2019년)에 의하여 연구되었음.

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