Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Imaging Diagnosis of Dilated Cardiomyopathy in a Maltese Dog

  • An, Soyon (Institute of Animal Medicine, Department of Veterinary Medical Imaging, College of Veterinary Medicine, Gyeongsang National University) ;
  • Park, Junghyun (Institute of Animal Medicine, Department of Veterinary Medical Imaging, College of Veterinary Medicine, Gyeongsang National University) ;
  • Mok, Jinsu (Institute of Animal Medicine, Department of Veterinary Medical Imaging, College of Veterinary Medicine, Gyeongsang National University) ;
  • Kim, Areum (Institute of Animal Medicine, Department of Veterinary Medical Imaging, College of Veterinary Medicine, Gyeongsang National University) ;
  • Han, Changhee (Institute of Animal Medicine, Department of Veterinary Medical Imaging, College of Veterinary Medicine, Gyeongsang National University) ;
  • Song, Joong Hyun (Ulsan S Animal Medical Center) ;
  • Yu, Dohyeon (Institute of Animal Medicine, Department of Veterinary Medical Imaging, College of Veterinary Medicine, Gyeongsang National University) ;
  • Hwang, Tae Sung (Institute of Animal Medicine, Department of Veterinary Medical Imaging, College of Veterinary Medicine, Gyeongsang National University) ;
  • Lee, Hee-Chun (Institute of Animal Medicine, Department of Veterinary Medical Imaging, College of Veterinary Medicine, Gyeongsang National University)
  • Received : 2020.07.09
  • Accepted : 2021.03.18
  • Published : 2021.06.30
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Abstract

A 6-year-old, spayed female, Maltese dog with tachypnea and dry cough was presented to Gyeongsang National University Veterinary Medical Teaching hospital. On physical examination, its respiration rate was 132 per minute. Decreased partial pressure of oxygen, partial pressure of carbon dioxide, and hyperlactatemia were found on arterial blood gas analysis. Its diastolic blood pressure was 80 mmHg. Auscultation revealed arrhythmia. Electrocardiogram revealed P pulmonale, P mitrale, and ventricular premature complexes. Thoracic radiographs revealed mild enlargement of both atrium and moderate enlargement of the left ventricular. There was also a moderate alveolar pattern in the right and caudal part of the left cranial lung lobe. Two-dimensional echocardiography showed enlargement of generalized four chambers without remarkable findings of valvular degeneration. M-mode echocardiography showed decreased left ventricular fractional shortening and enlarged left ventricular internal diameter at both end-systolic and end-diastolic. Color-flow Doppler imaging revealed eccentric turbulent flow starting below the left ventricular outflow tract and extending into the left atrium during systole. Spectral Doppler recordings revealed a high velocity flow through the mitral, tricuspid, aorta, and pulmonic regurgitation. Restrictive transmitral flow revealed high E-wave velocity, short E-wave deceleration time, and reduced A-wave velocity. There was also low ejection velocity thorough left ventricular out tract flow. Based on echocardiographic examination, dilated cardiomyopathy was the tentative diagnosis. The dog was medicated with inotropes, angiotensin converting enzyme inhibitor, and diuretics. At the 10-day following-up, the dog died suddenly. This report describes echocardiographic diagnosis and prognosis of dilated cardiomyopathy rarely reported in small breed dogs.

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References

  1. Alroy J, Rush JE, Freeman L, Amarendhra Kumar MS, Karuri A, Chase K, et al. Inherited infantile dilated cardiomyopathy in dogs: genetic, clinical, biochemical, and morphologic findings. Am J Med Genet 2000; 95: 57-66. https://doi.org/10.1002/1096-8628(20001106)95:1<57::AID-AJMG12>3.0.CO;2-O
  2. Beier P, Reese S, Holler PJ, Simak J, Tater G, Wess G. The role of hypothyroidism in the etiology and progression of dilated cardiomyopathy in Doberman Pinschers. J Vet Intern Med 2015; 29: 141-149. https://doi.org/10.1111/jvim.12476
  3. Boon JA. Dilated cardiomyopathy. In: Boon JA, editor. Veterinary echocardiography. 2nd ed. Chichester: Wiley-Blackwell. 2011: 381-395.
  4. Borgarelli M, Santilli RA, Chiavegato D, D'Agnolo G, Zanatta R, Mannelli A, et al. Prognostic indicators for dogs with dilated cardiomyopathy. J Vet Intern Med 2006; 20: 104-110. https://doi.org/10.1111/j.1939-1676.2006.tb02829.x
  5. Chetboul V. Canine dilated cardiomyopathy and other cardiomyopathies. In: de Madron E, Chetboul V, Bussadori C, editors. Clinical echocardiography of the dog and cat. St. Louis: Elsevier. 2016: 181-194.
  6. Cobb MA. Idiopathic dilated cardiomyopathy: advances in aetiology, pathogenesis and management. J Small Anim Pract 1992; 33: 113-118. https://doi.org/10.1111/j.1748-5827.1992.tb01092.x
  7. Delaney SJ, Kass PH, Rogers QR, Fascetti AJ. Plasma and whole blood taurine in normal dogs of varying size fed commercially prepared food. J Anim Physiol Anim Nutr (Berl) 2003; 87: 236-244. https://doi.org/10.1046/j.1439-0396.2003.00433.x
  8. Dukes-McEwan J, Borgarelli M, Tidholm A, Vollmar AC, Haggstrom J. Proposed guidelines for the diagnosis of canine idiopathic dilated cardiomyopathy. J Vet Cardiol 2003; 5: 7-19.
  9. Ettinger SJ. Myocardial diseases. In: Ettinger S, Feldman E, Cote E, editors. Textbook of veterinary internal medicine expert consult. 8th ed. St. Louis: Elsevier. 2017: 3071-3091.
  10. Fascetti AJ, Reed JR, Rogers QR, Backus RC. Taurine deficiency in dogs with dilated cardiomyopathy: 12 cases (1997-2001). J Am Vet Med Assoc 2003; 223: 1137-1141. https://doi.org/10.2460/javma.2003.223.1137
  11. Freeman LM, Stern JA, Fries R, Adin DB, Rush JE. Diet-associated dilated cardiomyopathy in dogs: what do we know? J Am Vet Med Assoc 2018; 253: 1390-1394. https://doi.org/10.2460/javma.253.11.1390
  12. Gavaghan BJ, Kittleson MD. Dilated cardiomyopathy in an American cocker spaniel with taurine deficiency. Aust Vet J 1997; 75: 862-868. https://doi.org/10.1111/j.1751-0813.1997.tb11253.x
  13. Harmon MW, Leach SB, Lamb KE. Dilated cardiomyopathy in standard schnauzers: retrospective study of 15 cases. J Am Anim Hosp Assoc 2017; 53: 38-44. https://doi.org/10.5326/JAAHA-MS-6506
  14. Kittleson MD, Keene B, Pion PD, Loyer CG. Results of the multicenter spaniel trial (MUST): taurine- and carnitine-responsive dilated cardiomyopathy in American cocker spaniels with decreased plasma taurine concentration. J Vet Intern Med 1997; 11: 204-211. https://doi.org/10.1111/j.1939-1676.1997.tb00092.x
  15. Martin MW, Stafford Johnson MJ, Strehlau G, King JN. Canine dilated cardiomyopathy: a retrospective study of prognostic findings in 367 clinical cases. J Small Anim Pract 2010; 51: 428-436. https://doi.org/10.1111/j.1748-5827.2010.00966.x
  16. Mattoon JS. Cardiomyopathy. In: Mattoon J, Nyland T, editors. Small animal diagnostic ultrasound. 3rd ed. St. Louis: Elsevier. 2015: 310-311.
  17. Nelson RW. Myocardial diseases of the dog. In: Nelson R, Couto CG, editors. Small animal internal medicine. 5th ed. St. Louis: Elsevier. 2014: 130-144.
  18. Oyama MA. Canine cardiomyopathy. In: Smith FWK, Tilley LP, Oyama M, Sleeper MM, editors. Manual of canine and feline cardiology. 5th ed. St. Louis: Elsevier. 2016: 139-150.
  19. Richardson P, McKenna W, Bristow M, Maisch B, Mautner B, O'Connell J, et al. Report of the 1995 World Health Organization/International Society and Federation of Cardiology Task Force on the Definition and Classification of cardiomyopathies. Circulation 1996; 93: 841-842. https://doi.org/10.1161/01.CIR.93.5.841
  20. Sanderson SL. Taurine and carnitine in canine cardiomyopathy. Vet Clin North Am Small Anim Pract 2006; 36: 1325-1343, vii-viii. https://doi.org/10.1016/j.cvsm.2006.08.010
  21. Schwarz T. Myocardial diseases. In: Schwarz T, Johnson V, editors. BSAVA Manual of canine and feline thoracic imaging. Quedgeley: British Small Animal Veterinary Association. 2008: 135-138.
  22. Simpson S, Edwards J, Ferguson-Mignan TF, Cobb M, Mongan NP, Rutland CS. Genetics of human and canine dilated cardiomyopathy. Int J Genomics 2015; 2015: 204823.
  23. Thrall DE. Cardiomyopathy. In: Thrall D, editor. Textbook of veterinary diagnostic radiology. 7th ed. St. Louis: Elsevier. 2018: 702-703.
  24. Tidholm A, Haggstrom J, Borgarelli M, Tarducci A. Canine idiopathic dilated cardiomyopathy. Part I. Aetiology, clinical characteristics, epidemiology and pathology. Vet J 2001; 162: 92-107. https://doi.org/10.1053/tvjl.2001.0571
  25. Tidholm A, Haggstrom J, Hansson K. Effects of dilated cardiomyopathy on the renin-angiotensin-aldosterone system, atrial natriuretic peptide activity, and thyroid hormone concentrations in dogs. Am J Vet Res 2001; 62: 961-967. https://doi.org/10.2460/ajvr.2001.62.961
  26. Ware WA. Myocardial diseases of the dog. In: Ware W, editor. Cardiovascular disease in small animal medicine. London: Manson Publishing Ltd. 2007: 280-292.
  27. Watanabe E, Ohsawa H, Noike H, Okamoto K, Tokuyama A, Kanai M, et al. Dilated cardiomyopathy associated with hyperthyroidism. Intern Med 1995; 34: 762-767. https://doi.org/10.2169/internalmedicine.34.762