Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Steroidal Saponins from Dracaena humilis (Dracaenaceae) and their Chemotaxonomic Significance

  • Received : 2021.03.13
  • Accepted : 2021.05.17
  • Published : 2021.06.30
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Abstract

A new steroidal saponin, (23S,24S)-spirosta-5,25(27)-diene-1𝛽,3𝛽,23,24-tetrol 1-O-((2,3-diacetyl-α-L-rhamnopyranosyl)-(1→2)-[𝛽-D-xylopyranosyl-(1→3)]-α-L-arabinopyranoside)-24-O-𝛽-D-glucopyranoside (humilisoside) together with the known 𝛽-sitosterol 3-O-glucopyranoside, adenosine, dioscin, and methylprotodioscin were isolated from the leaves of Dracaena humilis. Their structures were elucidated by spectral techniques including mass spectrometry (ESIMS, HRESIMS, tandem MS-MS), 1D NMR (1H, 13C NMR), 2D NMR (HSQC, 1H-1H COSY, HMBC, NOESY), chemical method as well as by comparison with spectroscopic data reported in the literature. The chemotaxonomic significance of the isolation of these compounds is discussed. This is the first report on the phytochemical investigation of D. humilis.

Keywords

Acknowledgement

This work was supported by TWAS through of a research grant (N° 09-152 RG/CHE/AF/AC I-UNESCO FR:3240230339) to Prof. Teponno. We are grateful to Prof. Dr. Till Opatz of the Institute of Organic Chemistry Johannes Gutenberg University Mainz, Germany for allowing the measurement of NMR and mass spectra.

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