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Antibacterial property of 4-hexylresorcinol incorporated in silk mat after sterilization

  • Kim, Seong-Gon (Dept. of Oral and Maxillofacial Surgery, College of Dentistry, Gangneung-Wonju National University) ;
  • Kweon, HaeYong (Sericultural and Apicultural Division, National Institute of Agricultural Science, RDA) ;
  • Jo, You-Young (Sericultural and Apicultural Division, National Institute of Agricultural Science, RDA)
  • Received : 2021.06.26
  • Accepted : 2021.06.29
  • Published : 2021.06.30

Abstract

When 4-hexylresorcinol (4HR) incorporated silk mat is used for clinical application, sterilization process is essential. In this study, 4HR incorporated silk mat was sterilized with ethylene oxide (EO) gas or autoclave, and then antibacterial property was evaluated. For the examination of micro-structure after the sterilization, scanning electron microscopic (SEM) exam and Fourier Transform Infrared (FT-IR) spectroscopy were also done. There was no gross difference after sterilization in SEM exam and FT-IR spectra. Antibacterial property of 4HR was also maintained after the sterilization. In conclusion, EO gas or autoclave did not damage the antibacterial property of 4HR in the silk mat.

Keywords

Acknowledgement

This study was conducted with the support of "Cooperative Research Program for Agriculture Science and Technology Development (Project no. PJ01562601)" Rural Development Administration, Republic of Korea.

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