Korean Journal of Radiology

The Korean Society of Radiology (대한영상의학회)
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Non-Infectious Granulomatous Lung Disease: Imaging Findings with Pathologic Correlation

  • Tomas Franquet (Department of Diagnostic Radiology, Hospital de Sant Pau, Universitat Autonoma de Barcelona) ;
  • Teri J. Franks (Department of Defense, Pulmonary & Mediastinal Pathology, The Joint Pathology Center) ;
  • Jeffrey R. Galvin (Department of Diagnostic Radiology, Chest Imaging, & Pulmonary Critical Care Medicine, University of Maryland School of Medicine) ;
  • Edson Marchiori (Department of Radiology, Hospital Universitario Clementino Fraga Filho-Universidade Federal do Rio de Janeiro) ;
  • Ana Gimenez (Department of Diagnostic Radiology, Hospital de Sant Pau, Universitat Autonoma de Barcelona) ;
  • Sandra Mazzini (Department of Diagnostic Radiology, Hospital de Sant Pau, Universitat Autonoma de Barcelona) ;
  • Takeshi Johkoh (Department of Radiology, Kansai Rosai Hospital) ;
  • Kyung Soo Lee (Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine (SKKU-SOM))
  • Received : 2020.08.31
  • Accepted : 2020.11.01
  • Published : 2021.08.01
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Abstract

Non-infectious granulomatous lung disease represents a diverse group of disorders characterized by pulmonary opacities associated with granulomatous inflammation, a relatively nonspecific finding commonly encountered by pathologists. Some lesions may present a diagnostic challenge because of nonspecific imaging features; however, recognition of the various imaging manifestations of these disorders in conjunction with patients' clinical history, such as age, symptom onset and duration, immune status, and presence of asthma or cutaneous lesions, is imperative for narrowing the differential diagnosis and determining appropriate management of this rare group of disorders. In this pictorial review, we describe the pathologic findings of various non-infectious granulomatous lung diseases as well as the radiologic features and high-resolution computed tomography imaging features.

Keywords

Acknowledgement

The views expressed in this article are those of the author (Teri J. Franks, MD) and do not reflect the official policy of the Department of the Army/Navy/Air Force, Department of Defense, or the U.S. Government. This Educational Exhibit was awarded with a Magna Cum Laude at RSNA 2019 Annual Meeting.

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