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Scalp metastasis of advanced gastric cancer

  • Ryu, Hyeong Rae (Department of Plastic and Reconstructive Surgery, Soonchunhyang University College of Medicine) ;
  • Lee, Da Woon (Department of Plastic and Reconstructive Surgery, Soonchunhyang University College of Medicine) ;
  • Choi, Hwan Jun (Department of Plastic and Reconstructive Surgery, Soonchunhyang University College of Medicine) ;
  • Kim, Jun Hyuk (Department of Plastic and Reconstructive Surgery, Soonchunhyang University College of Medicine) ;
  • Ahn, Hyein (Department of Pathology, Soonchunhyang University College of Medicine)
  • Received : 2021.03.31
  • Accepted : 2021.04.20
  • Published : 2021.06.20

Abstract

Head and neck cutaneous metastasis of advanced gastric cancer is uncommon, and scalp metastasis is particularly rare. We present the case of a 60-year-old man who was diagnosed with cutaneous metastasis on the scalp originating from advanced gastric cancer. The patient was referred to the plastic surgery department for a scalp mass near the hairline. He had been diagnosed with advanced gastric cancer and undergone total gastrectomy and Roux esophagojejunostomy 3 years previously. The differential diagnosis for a single flesh-colored nodule on the scalp included benign tumors such as epidermal cyst or lipoma; therefore, the patient underwent excision and biopsy. In the operative field, the mass was found to be located in the frontalis muscle. The biopsy result showed that the mass was a metastatic lesion of advanced gastric cancer. Whole-body computed tomography revealed a gastric tumor with blood vessel infiltration, peritoneal carcinomatosis, liver metastasis, and multiple disseminated subcutaneous metastases. Although scalp metastasis originating from an internal organ is extremely rare, plastic surgeons should always consider a metastatic lesion in the differential diagnosis if a patient with a scalp lesion has a history of malignant cancer.

Keywords

Acknowledgement

This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (2020R1A2C1100891), and was supported by Soonchunhyang University research fund.

References

  1. Lookingbill DP, Spangler N, Sexton FM. Skin involvement as the presenting sign of internal carcinoma: a retrospective study of 7316 cancer patients. J Am Acad Dermatol 1990;22:19-26. https://doi.org/10.1016/0190-9622(90)70002-Y
  2. Namikawa T, Munekage E, Munekage M, Maeda H, Yatabe T, Kitagawa H, et al. Subcutaneous metastasis arising from gastric cancer: a case report. Mol Clin Oncol 2017;6:515-6. https://doi.org/10.3892/mco.2017.1175
  3. Pereira WA, Humaire CR, Silva CS, Fernandes LH. Sister Mary Joseph's nodule: a sign of internal malignancy. An Bras Dermatol 2011;86(4 Suppl 1):S118-20.
  4. Brownstein MH, Helwig EB. Patterns of cutaneous metastases Arch Dermatol 1972;105:862-8. https://doi.org/10.1001/archderm.1972.01620090034008
  5. DU C, Hong R, Liu Y, Wang J, Zhang H, Yu X. Scalp metastasis from gastric cancer: a case report and literature review. Oncol Lett 2015;9:641-4. https://doi.org/10.3892/ol.2014.2708
  6. Cohen DC. A man with an umbilical ulcer. Medscape J Med 2008;10:11.
  7. Zhong J, Chen Y, Wang LJ. Emerging molecular basis of hematogenous metastasis in gastric cancer. World J Gastroenterol 2016;22:2434-40. https://doi.org/10.3748/wjg.v22.i8.2434
  8. Suk S, Shin HW, Yoon KC, Kim J. Aggressive cutaneous squamous cell carcinoma of the scalp. Arch Craniofac Surg 2020;21:363-7. https://doi.org/10.7181/acfs.2020.00381
  9. Lee DW, Ryu HR, Kim JH, Choi HJ, Ahn H. Isolated temporalis muscle metastasis of renal cell carcinoma. Arch Craniofac Surg 2021;22:66-70. https://doi.org/10.7181/acfs.2021.00031
  10. Kirchberger MC. Unusual presentation of a cutaneous metastasis in the face arising from gastric cancer: a case report. SAGE Open Med Case Rep 2018;6:2050313X18795080.
  11. Leiting JL, Grotz TE. Advancements and challenges in treating advanced gastric cancer in the West. World J Gastrointest Oncol 2019;11:652-64. https://doi.org/10.4251/wjgo.v11.i9.652