Imaging Science in Dentistry

Korean Academy of Oral and Maxillofacial Radiology (대한영상치의학회)
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Ghost cell odontogenic carcinoma: A case report

  • Panprasit, Wariya (Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Chulalongkorn University) ;
  • Lappanakokiat, Napas (Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Chulalongkorn University) ;
  • Kunmongkolwut, Sumana (Department of Oral Pathology, Faculty of Dentistry, Chulalongkorn University) ;
  • Phattarataratip, Ekarat (Department of Oral Pathology, Faculty of Dentistry, Chulalongkorn University) ;
  • Rochchanavibhata, Sunisa (Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Chulalongkorn University) ;
  • Sinpitaksakul, Phonkit (Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Chulalongkorn University) ;
  • Cholitgul, Wichitsak (Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Chulalongkorn University)
  • Received : 2020.10.28
  • Accepted : 2021.01.05
  • Published : 2021.06.30
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Abstract

Ghost cell odontogenic carcinoma (GCOC) is a rare malignant neoplasm characterized by the presence of ghost cells. It is considered to originate from either a calcifying odontogenic cyst(COC) or a dentinogenic ghost cell tumor(DGCT). Its clinical and radiographic characteristics are non-specific, including slow growth, locally aggressive behavior, and eventual metastasis. This case report describes a 43-year-old Thai man with plain radiographs and cone-beam computed tomographic images revealing a unilocular radiolucency with non-corticated borders surrounding an impacted left canine associated with radiopaque foci around the cusp tip. Based on the microscopic findings, the lesion was diagnosed as GCOC. Partial maxillectomy of the right maxilla was performed, and radiotherapy was administered. An obturator was made to support masticatory functions Three years later, the lesion showed complete bone remodeling and no signs of recurrence, and long-term follow-up was done regularly.

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References

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