Medical Lasers

Korean Society for Laser Medicine and Surgery (대한의학레이저학회)
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Clinical Application of Gold Nanoparticles for Diagnosis and Treatment

  • Baek, Seung-Kuk (Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine)
  • Received : 2021.05.07
  • Accepted : 2021.06.07
  • Published : 2021.06.30
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Abstract

Advances in nanobiotechnology have presented numerous possibilities of more effective diagnostic and therapeutic options. In particular, gold nanoparticles have demonstrated the potential for application in molecular imaging and treatment of cancers, including drug delivery system of certain target molecules, enhancement of radiation therapy, and photothermal treatment. This review discusses the properties, mechanism of action, and clinical application of gold nanoparticles. Although the safety of nanoparticles is yet to be ascertained, there is no doubt that in the future, nanotechnology will play an important role in the development and enhancement of a wide range of diagnostic and treatment modalities.

Keywords

Acknowledgement

This research was supported by the Clinical Trial Center of Korea University Anam Hospital (I1502411), the Korea Health Technlogy R&D Project (HI14C0748) through the Korea Health Industry Development Institute (KHIDI) by the Ministry of Health & Welfare, and the Basic Science Research Program through the National Research Foundation of Korea funded by the Ministry of Education (NRF-2016R1D1A1A02937362, NRF-2018R1D1A1A09083263).

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