The Journal of Pediatrics of Korean Medicine (대한한방소아과학회지)

The Association of Korean Oriental Pediatrics (대한한방소아과학회)
권호 표지
DOI QR코드

DOI QR Code

A Systematic Review of Economic Analysis on Idiopathic Short Stature

특발성 저신장의 경제성 평가 연구 경향 분석: 체계적 문헌고찰

  • Lee, Boram (Clinical Medicine Division, Korea Institute of Oriental Medicine) ;
  • Kwon, Chan-Young (Department of Oriental Neuropsychiatry, Dong-eui University College of Korean Medicine) ;
  • Jang, Soobin (Department of Preventive Medicine, College of Korean Medicine, Daegu Haany University)
  • 이보람 (한국한의학연구원 임상의학부) ;
  • 권찬영 (동의대학교 한의과대학 신경정신과학교실) ;
  • 장수빈 (대구한의대학교 한의과대학 예방의학교실)
  • Received : 2021.03.16
  • Accepted : 2021.05.21
  • Published : 2021.05.31
Download PDF
⟨ Previous Next ⟩

Abstract

Objectives We aimed to examine health-related economic analysis of available interventions on idiopathic short stature (ISS). Methods Eight studies were reviewed from English, Korean, and Chinese databases which were published up to December 24, 2020. Effectiveness, utility, and cost data were extracted from the studies and descriptive analysis of the individual studies was conducted Results Five studies were chosen. In the two economic evaluation studies, the incremental cost-effectiveness ratio (ICER) of growth hormone (GH) treatment was presented by performing cost-effectiveness analysis based on the deterministic decision tree approach for the GH and untreated group. Final adult height and direct medical costs were analyzed as effectiveness and cost outcomes. In 1 review article, an ICER of GH was presented based on systematic review on the effects of the GH treatment. In the two clinical trials, the effectiveness and cost of the 12 months Oriental medicine combination treatment were presented in comparison with the GH treatment alone. There were no literatures that provided utility data of available intervention on ISS. Conclusions The results of this study will be used as basic data for the economic analysis of Oriental medicine treatment on ISS in the future.

Keywords

Acknowledgement

본 연구는 보건복지부의 재원으로 한국보건산업진흥원의 보건의료기술연구개발사업 지원에 의하여 이루어진 것임 (과제고유번호: HF20C0103).

References

  1. Ranke MB. Towards a consensus on the definition of idiopathic short stature. Hormone Research. 1996;45 Suppl 2:64-6. https://doi.org/10.1159/000184851
  2. Lindsay R, Feldkamp M, Harris D, Robertson J, Rallison M. Utah Growth Study: growth standards and the prevalence of growth hormone deficiency. J Pediatr. 1994; 125(1):29-35. https://doi.org/10.1016/S0022-3476(94)70117-2
  3. Wheeler PG, Bresnahan K, Shephard BA, Lau J, Balk EM. Short stature and functional impairment: a systematic review. Arch Pediatr Adolesc Med. 2004;158(3): 236-43. https://doi.org/10.1001/archpedi.158.3.236
  4. Zlotkin D, Varma SK. Psychosocial effects of short stature. Indian J Pediatr. 2006;73(1):79-80. https://doi.org/10.1007/BF02758266
  5. Cuttler L, Silvers JB. Growth hormone and health policy. J Clin Endocrinol Metab. 2010;95(7):3149-53. https://doi.org/10.1210/jc.2009-2688
  6. Huh K, Park MJ. Questionnaire-based analysis of growth-promoting attempts among children visiting a university growth clinic. Korean J Pediatr. 2009;52(5): 576-80. https://doi.org/10.3345/kjp.2009.52.5.576
  7. Theunissen NC, Kamp GA, Koopman HM, Zwinderman KA, Vogels T, Wit JM. Quality of life and self-esteem in children treated for idiopathic short stature. J pediatr. 2002;140(5):507-15. https://doi.org/10.1067/mpd.2002.123766
  8. Deodati A, Cianfarani S. Impact of growth hormone therapy on adult height of children with idiopathic short stature: systematic review. BMJ. 2011;342:c7157. https://doi.org/10.1136/bmj.c7157
  9. Lee KH. Growth hormone therapy in short stature children. J Korean Med Assoc. 2008;51(9):849-55. https://doi.org/10.5124/jkma.2008.51.9.849
  10. Rudmik L, Drummond M. Health economic evaluation: important principles and methodology. The Laryngoscope. 2013;123(6):1341-7. https://doi.org/10.1002/lary.23943
  11. Lee B, Kwon CY. Review of economic analysis of available interventions on idiopathic short stature: a protocol for systematic review and meta-analysis. Medicine. 2021; 100(7):e24871. https://doi.org/10.1097/MD.0000000000024871
  12. Bryant J, Cave C, Mihaylova B, Chase D, McIntyre L, Gerard K, Milne R. Clinical effectiveness and cost-effectiveness of growth hormone in children: a systematic review and economic evaluation. Health Technol Assess. 2002;6(18):1-168. https://doi.org/10.3310/hta6180
  13. Lee JM, Davis MM, Clark SJ, Hofer TP, Kemper AR. Estimated cost-effectiveness of growth hormone therapy for idiopathic short stature. Arch Pediatr Adolesc Med. 2006;160(3):263-9. https://doi.org/10.1001/archpedi.160.3.263
  14. Zhang XY. To explore the treatment of idiopathic short stature with TCM-WM and gene of ISS. Tianjin University of Traditional Chinese Medicine (Master's thesis). 2017.
  15. Li J. The clinical curative effect observation on the traditional Chinese medicine and comprehensive interference in the treatment of idiopathic short stature. Shandong University of Traditional Chinese Medicine (Master's thesis). 2012.
  16. Hyun EH, Lee HY, Kim HW, Kim HM, Kim EJ, Kim SJ, Song YG, Kim YI, Nam WJ, Seo DH, Lee SH, Kim N. Clinical and cost-effectiveness of collaborative traditional Korean and Western medicine treatment for low back pain: a protocol for a prospective observational exploratory study. Medicine. 2018;97(39): e12595. https://doi.org/10.1097/MD.0000000000012595
  17. Kim SH, Jo J, Kim DI. The effectiveness, safety, and economic evaluation of Korean medicine for unexplained infertile women: a multi-center, prospective, observational study protocol. Medicine. 2017;96(51): e9360. https://doi.org/10.1097/MD.0000000000009360
  18. Lee HY, Kang HW, Kim N, Hyun EH, Seo JH, Lyu YS, Jung IC, Kim GW, Park B, Choi SY, Kim HW, Kim HM. Effectiveness of collaborative treatment using Korean and Western medicine for mild cognitive impairment or dementia: a protocol for a prospective observational exploratory study. Medicine. 2018;97(35): e12098. https://doi.org/10.1097/md.0000000000012098