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유방암 수술 후 액와 림프절에 발생한 Progressive Transformation of Germinal Centers: 증례 보고

Progressive Transformation of Germinal Centers in Axillary Lymph Nodes Mimicking Metastatic Lymphadenopathy after Breast Cancer Surgery: A Case Report

  • 박상은 (고려대학교 안암병원 영상의학과) ;
  • 조규란 (고려대학교 안암병원 영상의학과) ;
  • 송성은 (고려대학교 안암병원 영상의학과) ;
  • 우옥희 (고려대학교 구로병원 영상의학과) ;
  • 서보경 (고려대학교 안산병원 영상의학과) ;
  • 이정현 (고려대학교 안암병원 병리과)
  • Sang Eun Park (Department of Radiology, Korea University Anam Hospital) ;
  • Kyu Ran Cho (Department of Radiology, Korea University Anam Hospital) ;
  • Sung Eun Song (Department of Radiology, Korea University Anam Hospital) ;
  • Ok Hee Woo (Department of Radiology, Korea University Guro Hospital) ;
  • Bo Kyoung Seo (Department of Radiology, Korea University Ansan Hospital) ;
  • Jeonghyun Lee (Department of Pathology, Korea University Anam Hospital)
  • 투고 : 2020.05.25
  • 심사 : 2020.07.28
  • 발행 : 2021.03.01

초록

Progressive transformation of germinal centers (이하 PTGC)는 드물게 나타나는 양성 림프절 질환으로, 주로 만성적인 림프절 비대의 형태로 나타난다. 주로 한 개 또는 여러 개의 림프절의 무통성 비대로 나타나며, 가장 흔히 침범하는 부위는 경부 림프절, 다음으로 액와부와 서혜부 림프절로 알려져 있다. 일부 환자들에서는 조직병리에서 림프종이 함께 존재하기도 하지만, PTGC 자체는 전암병변으로 인식되지는 않는다. 조직학적으로 PTGC로 진단되는 경우도 적지만, 이에 대한 영상의학적 소견은 거의 보고된 바가 없다. 이에 저자들은 침윤성 유방암 환자에서 수술 후 반대편 액와부 림프절 비대로 나타나 전이성 림프절로 오인한 PTGC 증례의 영상 소견을 보고하고자 한다.

Progressive transformation of germinal centers (PTGC) is a rarely diagnosed, benign disease of the lymph nodes that commonly manifests as chronic lymphadenopathy. PTGC may be characterized by single or multiple non-tender lymph nodes, and it commonly involves the cervical, axillary, and inguinal areas. Although PTGC is identified with concurrent lymphoma in some patients, it is not considered as a premalignant entity. Histopathologic diagnosis of PTGC is rarely made, and imaging findings have been reported in very few studies. We present a case of PTGC that occurred at the contralateral axillary lymph nodes and mimicked metastatic lymphadenopathy after breast cancer surgery. We also discuss its imaging findings.

키워드

참고문헌

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