Pediatric Gastroenterology, Hepatology & Nutrition

The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition (대한소아소화기영양학회)
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Growth Patterns of Indonesian Infants with Cow's Milk Allergy and Fed with Soy-Based Infant Formula

  • Received : 2010.09.21
  • Accepted : 2021.01.02
  • Published : 2021.05.15
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Abstract

Purpose: The use of soy-based infant formula has increased widely in infants with cow's milk allergy (CMA). This study aimed to provide evidence on the growth pattern of CMA infants fed with soy-based infant formula in an Indonesian setting. Methods: A multi-site, intervention study was conducted among full-term and normal birth weight CMA infants. Within six months, the subjects were provided with a soy-based infant formula. Weight, height, and head circumference were measured at baseline, weeks 4, 8, 12, 16, 20, and 24. Adverse events were recorded by scoring atopic dermatitis and symptom-based clinical scores. Results: Based on the World Health Organization growth chart, we found that most of subjects had normal nutritional status for weight-for-age, length-for-age, weight-for-length, and head-circumference-for-age. There were statistically significant differences between baseline and end-line for weight-for-age, length-for-age, weight-for-length, and head circumference-for-age nutritional status. No allergic symptoms or intolerance toward soy formula were observed at the end of the intervention period. Conclusion: These results show that infants fed with soy-based infant formula have a normal pattern of growth.

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References

  1. Host A. Frequency of cow's milk allergy in childhood. Ann Allergy Asthma Immunol 2002;89(6 Suppl 1):33-7. https://doi.org/10.1016/S1081-1206(10)62120-5
  2. Ikatan Dokter Anak Indonesia. [Indonesian Pediatric Society recommendation: diagnosis and management of cow milk allergy]. Jakarta: Ikatan Dokter Anak Indonesia, 2014. Indonesian.
  3. Tzifi F, Grammeniatis V, Papadopoulos M. Soy- and rice-based formula and infant allergic to cow's milk. Endocr Metab Immune Disord Drug Targets 2014;14:38-46. https://doi.org/10.2174/1871530314666140121144604
  4. Bhatia J, Greer F; American Academy of Pediatrics Committee on Nutrition. Use of soy protein-based formulas in infant feeding. Pediatrics 2008;121:1062-8. https://doi.org/10.1542/peds.2008-0564
  5. Ferrari GG, Eng PA. IgE-mediated food allergies in Swiss infants and children. Swiss Med Wkly 2011;141:w13269.
  6. Rozenfeld P, Docena GH, Anon MC, Fossati CA. Detection and identification of a soy protein component that cross-reacts with caseins from cow's milk. Clin Exp Immunol 2002;130:49-58. https://doi.org/10.1046/j.1365-2249.2002.t01-1-01935.x
  7. Natale M, Bisson C, Monti G, Peltran A, Garoffo LP, Valentini S, et al. Cow's milk allergens identification by two-dimensional immunoblotting and mass spectrometry. Mol Nutr Food Res 2004;48:363-9. https://doi.org/10.1002/mnfr.200400011
  8. ESPGHAN Committee on Nutrition, Agostoni C, Axelsson I, Goulet O, Koletzko B, Michaelsen KF, et al. Soy protein infant formulae and follow-on formulae: a commentary by the ESPGHAN Committee on Nutrition. J Pediatr Gastroenterol Nutr 2006;42:352-61. https://doi.org/10.1097/01.mpg.0000189358.38427.cd
  9. Fomon SJ. Introduction to section IV. In: Hamburger RN, ed. Food intolerance in infancy: allergology, immunology, and gastroenterology. Carnation Nutrition Education Series. Vol 1. New York: Raven Press, 1989:201.
  10. American Academy of Pediatrics. Committee on Nutrition. American Academy of Pediatrics. Committee on Nutrition. Soy protein-based formulas: recommendations for use in infant feeding. Pediatrics 1998;101(1 Pt 1):148-53. https://doi.org/10.1542/peds.101.1.148
  11. Lasekan JB, Ostrom KM, Jacobs JR, Blatter MM, Ndife LI, Gooch WM 3rd, et al. Growth of newborn, term infants fed soy formulas for 1 year. Clin Pediatr (Phila) 1999;38:563-71. https://doi.org/10.1177/000992289903801001
  12. Vandenplas Y, Hegar B. Soy-based infant nutrition: a review. Paediatr Indones 2014;54:62-6. https://doi.org/10.14238/pi54.1.2014.62-6
  13. Han YH, Yon M, Han HS, Johnston KE, Tamura T, Hyun T. Zinc status and growth of Korean infants fed human milk, casein-based, or soy-based formula: three-year longitudinal study. Nutr Res Pract 2011;5:46-51. https://doi.org/10.4162/nrp.2011.5.1.46
  14. Seppo L, Korpela R, Lonnerdal B, Metsaniitty L, Juntunen-Backman K, Klemola T, et al. A follow-up study of nutrient intake, nutritional status, and growth in infants with cow milk allergy fed either a soy formula or an extensively hydrolyzed whey formula. Am J Clin Nutr 2005;82:140-5. https://doi.org/10.1093/ajcn/82.1.140
  15. World Health Organization. WHO child growth standards: length/height-for-age, weight-for-age, weight-for-length, weight-for-height and body mass index-for-age: methods and development [Internet]. Geneva: World Health Organization; 2006 [cited 2020 Jul 17]. Available from: https://www.who.int/childgrowth/standards/Technical_report.pdf
  16. Hui LL, Schooling CM, Cowling BJ, Leung SS, Lam TH, Leung GM. Are universal standards for optimal infant growth appropriate? Evidence from a Hong Kong Chinese birth cohort. Arch Dis Child 2008;93:561-5. https://doi.org/10.1136/adc.2007.119826
  17. Dwipoerwantoro PG, Mansyur M, Oswari H, Makrides M, Cleghorn G, Firmansyah A. Growth of Indonesian infants compared with World Health Organization growth standards. J Pediatr Gastroenterol Nutr 2015;61:248-52. https://doi.org/10.1097/MPG.0000000000000770
  18. American Academy of Pediatrics. Committee on Nutrition. Hypoallergenic infant formulas. Pediatrics 2000;106(2 Pt 1):346-9. https://doi.org/10.1542/peds.106.2.346
  19. Candreva AM, Smaldini PL, Curciarello R, Cauerhff A, Fossati CA, Docena GH, et al. Cross-reactivity between the soybean protein p34 and bovine caseins. Allergy Asthma Immunol Res 2015;7:60-8. https://doi.org/10.4168/aair.2015.7.1.60
  20. Strom BL, Schinnar R, Ziegler EE, Barnhart KT, Sammel MD, Macones GA, et al. Exposure to soy-based formula in infancy and endocrinological and reproductive outcomes in young adulthood. JAMA 2001;286:807-14. https://doi.org/10.1001/jama.286.7.807