DOI QR코드

DOI QR Code

Effects of Action Observation Training and Mirror Therapy on the Electroencephalograms of Stroke Patients

  • Lee, Ho Jung (Department of Rehabilitation Science, Graduate school, Daegu University) ;
  • Lee, Jong Su (Department of Rehabilitation Science, Graduate school, Daegu University) ;
  • Kim, Young Mi (Department of Physical Therapy, Andong Science College)
  • 투고 : 2021.03.10
  • 심사 : 2021.04.25
  • 발행 : 2021.04.30

초록

Purpose: This study examined the effectiveness of action observation training (AOT) and mirror therapy in improving the electroencephalograms (EEG) of stroke patients. Methods: Patients were allocated randomly to three groups: an action observation training with activity (AOTA) group (n=12), a mirror therapy with activity (MTA) group (n=11), and an AOT-only group (n=12). All groups received conventional physiotherapy in five 60-minute sessions over six weeks. The AOTA, MTA, and AOT groups practiced AOTA, MTA, and AOT, respectively, in three 30-minute sessions over six weeks. The differences between the pre- and post-treatment EEGs were assessed using a paired t-test. Comparisons between the groups were performed using one-way ANOVA. Results: The participants in the AOTA and MTA groups showed significant improvement in the EEG. AOTA improved the alpha waves of the prefrontal, temporal, and parietal lobes significantly (p<0.05). MTA improved the alpha waves of the temporal lobe significantly (p<0.05). AOT did not result in significant improvement Conclusion: AOTA and MTA improve stroke patients' EEGs. Mirror neuron activation combined with conventional stroke physiotherapy promotes motor recovery and functioning. The effect is enhanced when the actions are executed after observation. Further research into mirror neuron activation will be needed to develop methods to improve the EEGs of stroke patients.

키워드

과제정보

This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (2020R1I1A1A01053491).

참고문헌

  1. Higginson JS, Zajac FE, Neptune RR et al. Muscle contributions to support during gait in an individual with post-stroke hemiparesis. J Biomech. 2006;39(10):1769-77. https://doi.org/10.1016/j.jbiomech.2005.05.032
  2. Kautz SA, Patten C. Interlimb influences on paretic leg function in post-stroke hemiparesis. J Neurophysiol. 2005;93(5):2460-73. https://doi.org/10.1152/jn.00963.2004
  3. Kwakkel G, van Peppen R, Wagenaar RC et al. Effects of augmented exercise therapy time after stroke: a meta-analysis. Stroke. 2004;35(11): 2529-39. https://doi.org/10.1161/01.str.0000143153.76460.7d
  4. Sutbeyaz S, Yavuzer G, Sezer N et al. Mirror therapy enhances lower-extremity motor recovery and motor functioning after stroke: a randomized controlled trial. Arch Phys Med Rehabil. 2007;88(5):555-9. https://doi.org/10.1016/j.apmr.2007.02.034
  5. Bellelli G, Buccino G, Bernardini B et al. Action observation treatment improves recovery of postsurgical orthopedic patients: evidence for a top-down effect? Arch Phys Med Rehabil. 2010;91(10):1489-94. https://doi.org/10.1016/j.apmr.2010.07.013
  6. Cho HY, Kim JS, Lee GC. Effects of motor imagery training on balance and gait abilities in post-stroke patients: a randomized controlled trial. Clin Rehabil. 2013;27(8):675-80. https://doi.org/10.1177/0269215512464702
  7. Zentgraf K, Stark R, Reiser M et al. Differential activation of pre-SMA and SMA proper during action observation: effects of instructions. Neuroimage. 2005;26(3):662-72. https://doi.org/10.1016/j.neuroimage.2005.02.015
  8. Kim SH, Cho JS. Action observation and cortical connectivity: evidence from EEG analysis. J Kor Phys Ther. 2016;28(6):398-407. https://doi.org/10.18857/jkpt.2016.28.6.398
  9. Rizzolatti G, Fogassi L, Gallese V. Neurophysiological mechanisms underlying the understanding and imitation of action. Nat Rev Neurosci. 2001;2(9):661-70. https://doi.org/10.1038/35090060
  10. Buccino G, Binkofski F, Riggio L et al. The mirror neuron system and action recognition. Brain Lang. 2004;89(2):370-6. https://doi.org/10.1016/S0093-934X(03)00356-0
  11. Ehrsson HH, Spence C, Passingham REJS. That's my hand! Activity in premotor cortex reflects feeling of ownership of a limb. Science. 2004; 305(5685):875-7. https://doi.org/10.1126/science.1097011
  12. Thirumala P, Hier DB, Patel P. Motor recovery after stroke: Lessons from functional brain imaging. Neurol Re. 2002;24(5):453-8. https://doi.org/10.1179/016164102101200320
  13. Bhasin A, Srivastava MP, Kumaran SS et al. Neural interface of mirror therapy in chronic stroke patients: a functional magnetic resonance imaging study. Neurol India. 2012;60(6):570. https://doi.org/10.4103/0028-3886.105188
  14. Thieme H, Bayn M, Wurg M et al. Mirror therapy for patients with severe arm paresis after stroke-a randomized controlled trial. Clin Rehabil. 2013;27(4):314-24. https://doi.org/10.1177/0269215512455651
  15. Wing K. Effect of neurofeedback on motor recovery of a patient with brain injury: a case study and its implications for stroke rehabilitation. Top Stroke Rehabil. 2001;8(3):45-53. https://doi.org/10.1310/4G2F-5PLV-RNM9-BGGN
  16. Sutbeyaz S, Yavuzer G, Sezer N et al. Mirror therapy enhances lower-extremity motor recovery and motor functioning after stroke: a randomized controlled trial. Arch Phys Med Rehabil. 2007;88(5):555-9. https://doi.org/10.1016/j.apmr.2007.02.034
  17. Chariter D, Chariter L. QEEG assessment of traumatic brain injury and stroke patients. J Neurotherapy. 2003;7(1)113-34. https://doi.org/10.1300/J184v07n01_11
  18. Foxe JJ, Snyder AC. The role of alpha-band brain oscillations as a sensory suppression mechanism during selective attention. Front Psychol. 2011;2:154. https://doi.org/10.3389/fpsyg.2011.00154
  19. Cannon EN, Yoo KH, Vanderwert RE et al. Action experience, more than observation, influences mu rhythm desynchronization. Plos one. 2014;9(3):e92002. https://doi.org/10.1371/journal.pone.0092002
  20. Kim SG, Kim CS, Kim K. The effect of EEG through proprioceptive exercise and computerized cognitive therapy on stroke. J Korean Soc Phy Med. 2013;8(4):505-12. https://doi.org/10.13066/kspm.2013.8.4.505
  21. Kim JH, Lee BH, Lee HS et al. Differences in brain waves of normal persons and stroke patients during action observation and motor imagery. J Phys Ther Sci. 2014;26(2):215-8. https://doi.org/10.1589/jpts.26.215
  22. Brunner IC, Skouen JS, Ersland L et al. Plasticity and response to action observation: a longitudinal fMRI study of potential mirror neurons in patients with subacute stroke. Neurorehabil Neural Repair. 2014;28(9): 874-84. https://doi.org/10.1177/1545968314527350
  23. Small SL, Buccino G, Solodkin A. Brain repair after stroke-a novel neurological model. Nat Rev Neurol. 2013;9(12):698-707. https://doi.org/10.1038/nrneurol.2013.222
  24. Grezes J. Top down effect of strategy on the perception of human biological motion: a pet investigation. Cogn Neuropsychol. 1998;15(6-8): 553-82. https://doi.org/10.1080/026432998381023
  25. Rizzolatti G, Craighero L. The mirror-neuron system. Annu Rev Neurosci. 2004;27:169-92. https://doi.org/10.1146/annurev.neuro.27.070203.144230
  26. van der Hiele K, Vein A, Kramer C et al. Memory activation enhances EEG abnormality in mild cognitive impairment. Neurobiol Aging. 2007; 28(1):85-90.
  27. Egner T, Zech T, Gruzelier JH. The effects of neurofeedback training on the spectral topography of the electroencephalogram. Clin Neurophysiol. 2004;115(11):2452-60. https://doi.org/10.1016/j.clinph.2004.05.033
  28. Han K. The effect of 3d image action observation on the mirror neuron activity of normal subjects and people with chronic stroke. Seonam University. Dissertation of Doctorate Degree. 2012.
  29. Fox NA, Bakermans-Kranenburg MJ, Yoo KH et al. Assessing human mirror activity with EEG mu rhythm: a meta-analysis. Psychol Bull. 2016; 142(3):291. https://doi.org/10.1037/bul0000031
  30. Ewan LM, Smith NC, Holmes PS. Disruption to the aspects of imagery vividness after stroke. J Ment Imagery. 2010;34(3):3-14.