DOI QR코드

DOI QR Code

A Study on Polycarbonate Microfabrication Using a Pneumatic Hot Press

공압 핫프레스를 이용한 마이크로 폴리카보네이트 성형에 관한 연구

  • Yeo, Changyeong (School of Mechanical Convergence Engineering, KYUNGNAM UNIV) ;
  • Park, Taehyun (School of Mechanical Engineering, KYUNGNAM UNIV.)
  • 여창영 (경남대학교 기계융합공학부) ;
  • 박태현 (경남대학교 기계공학부)
  • Received : 2021.01.24
  • Accepted : 2021.03.19
  • Published : 2021.04.30

Abstract

Thermoplastic microfluidic devices are used in BioMEMS for medical and biotechnology applications, such as gene extraction, DNA analysis, and virus detection. In this research, a simple fabrication protocol with a commercially available pneumatic hot press is proposed and demonstrated for polycarbonate microfluidic devices. Microfluidic channels with a width of 200 ㎛ and a height of 10 ㎛ were designed and machined onto a brass plate as a mold insert using a CNC milling machine. The resulting microfluidic channels on the mold insert were assessed and found to have an actual width of 198 ㎛ and a height of 10 ± 0.25 ㎛. The microfluidic channels were replicated on a polycarbonate sheet using the proposed replication technique at 146℃ for 20 minutes under a constant load of 2400 kgf. The devices were then naturally cooled to 100℃ while maintaining the same pressure. It was found that the microchannels were successfully replicated in the polycarbonate, with a width of 198 ㎛ and a height of 10.07 ㎛. The proposed replication technique thus offers the rapid mass production of high-quality microfluidic devices at a low cost with a process that, unlike conventional photolithography systems, does not require expensive equipment.

Keywords

References

  1. Kang, J. Y. and Kim, T. S., "Nanobiosensor/chip reserch trend," Electrical and electronic materials, Vol 17, No. 4, pp. 5-15, 2004.
  2. Kim, Y. K., Oh, B. K. and Choi, J. W., "Planning Special: Nano Biosensor Technology Development; Nano Biochip Technology Development Trend," Industrial Chemistry Outlook, Vol. 9, No. 2, pp. 19-27, 2006.
  3. Becker, H., & Gartner, C. "Polymer microfabrication technologies for microfluidic systems," Analytical and Bioanalytical Chemistry, Vol. 390, No. 1, pp. 89-111, 2007. https://doi.org/10.1007/s00216-007-1692-2
  4. Velten, T., Ruf, H. H., Barrow, D., Aspragathos, N., Lazarou, P., Erik Jung, Wackerle, M. "Packaging of bio-MEMS: strategies, technologies, and applications," IEEE Transactions on Advanced Packaging, Vol. 28, No. 4, pp. 533-546. 2005. https://doi.org/10.1109/TADVP.2005.858427
  5. Lee, N. E., "A microfluidic channel for lab-on-a-chip using PDMS and a study of reaction with organic solvents," A Thesis for a master, Sungkyunkwan University, Republic of korea, 2012.
  6. Hogan, B. T., Dyakov, S. A., Brennan, L. J., Younesy, S., Perova, T. S., Gun'ko, Y. K., ... Baldycheva, A. "Dynamic in-situ sensing of fluid-dispersed 2D materials integrated on microfluidic Si chip. Scientific Reports," Scientific reports, Vol. 7, No. 1, 2017.
  7. Kim, J. K., Choi, S. H. and Go, S. H., "Improved of Mechanical Properties and Functionalization of Polycarbonate by Adding Carbon Materials," Journal of the Korean Society of Manufacturing Process Engineers, Vol. 19, No. 10, pp. 59-67, 2020.
  8. Park, D. J., "A Study on Polymer Thermal Bonding System Using Boiling Point Control Chamber," A Thesis for a master, Kyungnam University, Republic of Korea, 2016.
  9. Li, Y., Wang, Z., Ou, L. M. L., & Yu, H.-Z. "DNA Detection on Plastic: Surface Activation Protocol To Convert Polycarbonate Substrates to Biochip Platforms. Analytical Chemistry," Analytical Chemistry, Vol. 79, No. 2, 426-433, 2007. https://doi.org/10.1021/ac061134j
  10. Han, C. M. and Lee, B. K, "Effect of Processing Parameters in Surface Machining of Plastic Materials," Journal of the Korean Society of Manufacturing Process Engineers, Vol. 15, No. 5, pp. 109-116, 2016. https://doi.org/10.14775/ksmpe.2016.15.5.109
  11. Cai, Z., Chen, H., Chen, B., & Huang, C. "A gravity driven micro flow injection wetting film extraction system on a polycarbonate chip," Talanta, Vol. 68, No. 3, pp. 895-901, 2006. https://doi.org/10.1016/j.talanta.2005.06.037