Journal of Convergence Korean Medicine (대한융합한의학회지)

Academy of Convergence Korean Medicine (대한융합한의학회)
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A Study on Cases and Clinical Trials Applying Topical Agents Including Natural Products for Atopic Dermatitis Treatment

천연물 외용제를 적용한 아토피피부염 증례 및 임상 연구 고찰

  • Gwang-Yeel Seo (Department of Clinical Korean Medicine, Graduate School of Korean Medicine, Kyung Hee University) ;
  • Kyuseok Kim (Department of Ophthalmology, Otolaryngology and Dermatology of Korean Medicine, College of Korean Medicine, Kyung Hee University)
  • 서광일 (경희대학교 한의과대학원 임상한의학과 (안이비인후피부과 전공)) ;
  • 김규석 (경희대학교 한의과대학 안이비인후피부과 교실)
  • Received : 2021.07.05
  • Accepted : 2021.12.26
  • Published : 2021.12.31
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Abstract

Objectives: To investigate the characteristics of topical agents including natural products using for atopic dermatitis treatment via a review on the cases and clinical trials. Methods: Through a search on Pubmed, EMBASE, Cochrane library, DBPIA, NDSL, and OASIS, we selected papers that applied natural products externally for atopic dermatitis and analyzed them. Results: Finally, Seventeen papers were selected. As the primary outcome, changes in the SCORAD and EASI, were the most used. The most frequent type of external formulation was cream. In terms of the frequency of use, it was used at least twice a day in all studies. When evaluated based on SCORAD, EASI, SH and TEWL, the improvement effect on atopic dermatitis was highest when the ointment formulation and the moisturizer formulation were used. A few side effects of topical agents including natural products were observed, but most were mild symptoms and no serious side effects occurred. Conclusion: This study is meaningful in that it has drawn a significant trend for studies that have been published in the last 5 years that contain a single intervention for topical agents including natural products, and that it presents the direction and evidence for the application of external therapy to increase the therapeutic effect of atopic dermatitis.

Keywords

References

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