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Lymph Node Ratio System for N Staging of Gastric Cancer: Challenging for Universal Application But Useful for the Prognostic Prediction of Individual Patients

  • Kong, Seong-Ho (Department of Surgery, Seoul National University Hospital)
  • Published : 2021.03.31

Abstract

Keywords

References

  1. Marchet A, Mocellin S, Ambrosi A, Morgagni P, Garcea D, Marrelli D, et al. The ratio between metastatic and examined lymph nodes (N ratio) is an independent prognostic factor in gastric cancer regardless of the type of lymphadenectomy: results from an Italian multicentric study in 1853 patients. Ann Surg 2007;245:543-552. https://doi.org/10.1097/01.sla.0000250423.43436.e1
  2. Kong SH, Lee HJ, Ahn HS, Kim JW, Kim WH, Lee KU, et al. Stage migration effect on survival in gastric cancer surgery with extended lymphadenectomy: the reappraisal of positive lymph node ratio as a proper N-staging. Ann Surg 2012;255:50-58. https://doi.org/10.1097/SLA.0b013e31821d4d75
  3. Park J, Jeon CH, Kim SJ, Seo HS, Song KY, Lee HH. A novel approach for gastric cancer staging in elderly patients based on the lymph node ratio. J Gastric Cancer 2021;21:84-92. https://doi.org/10.5230/jgc.2021.21.e9
  4. Zhu K, Jin H, Li Z, Gao Y, Zhang Q, Liu X, et al. The prognostic value of lymph node ratio after neoadjuvant chemotherapy in patients with locally advanced gastric adenocarcinoma. J Gastric Cancer 2021;21:49-62. https://doi.org/10.5230/jgc.2021.21.e5
  5. Son SY, Kong SH, Ahn HS, Park YS, Ahn SH, Suh YS, et al. The value of N staging with the positive lymph node ratio, and splenectomy, for remnant gastric cancer: a multicenter retrospective study. J Surg Oncol 2017;116:884-893. https://doi.org/10.1002/jso.24737
  6. Kim DJ, Kim W. Is lymph node size a reliable factor for estimating lymph node metastasis in early gastric cancer? J Gastric Cancer 2018;18:20-29. https://doi.org/10.5230/jgc.2018.18.e1

Cited by

  1. Lymph Node Involvement in Advanced Gastric Cancer in the Era of Multimodal Treatment-Oncological and Surgical Perspective vol.13, pp.10, 2021, https://doi.org/10.3390/cancers13102509