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A case of Nummular Eczema Treatment Improved through Korean Medicine : Focus on Hwangryeonagyo-tang and Mahwangbujasesin-tang

한방치료를 통해 개선된 화폐상 습진 치험 1례 : 황련아교탕(黃蓮阿膠湯)과 마황부자세신탕(麻黃附子細辛湯)을 중심으로

  • Jin, Han-Sol (Dept. of korean Medicine Ophthalmology & Otolaryngology & Dermatology, Clinical Korean Medicine, Dong-Eui University) ;
  • Yoon, Hwa-Jung (Dept. of korean Medicine Ophthalmology & Otolaryngology & Dermatology, Clinical Korean Medicine, Dong-Eui University) ;
  • Ko, Woo-Shin (Dept. of korean Medicine Ophthalmology & Otolaryngology & Dermatology, Clinical Korean Medicine, Dong-Eui University)
  • 진한솔 (동의대학교 한의과대학 안이비인후피부과학 교실) ;
  • 윤화정 (동의대학교 한의과대학 안이비인후피부과학 교실) ;
  • 고우신 (동의대학교 한의과대학 안이비인후피부과학 교실)
  • Received : 2021.01.03
  • Accepted : 2021.01.23
  • Published : 2021.02.25

Abstract

Objectives : The purpose of this study is to report the effect of Hwangryeonagyo-tang and Mahwangbujasesin-tang(《Shanghanlun》 prescription) on whole-body nummular eczema. Methods : We treated a female patient in her early twenties who has whole-body nummular eczema with Korean medicine. She was treated from 2020.10.8 to 2020.12.11. In this period, she received admission treatments twice because of the recurrence of the symptoms after the first admission. During the treatment, the two herbal medicines were changed depending on the patient's condition. 'Hwangryeonagyo-tang' and 'Mahwangbujasesin-tang' were used as herbal medicine. In addition, herbal external preparations and acupuncture treatment were also performed. The evaluation was conducted by photo comparison, VAS, and DLQI. Blood tests were also conducted for safety assessments. Results : After two months of treatment, the patient's condition improved. The itching and heat sensation decreased, and scabs were placed on the lesion of the eczema, reducing the oozing. VAS of itching decreased from 8 to 0. DLQI was also improved, and the stability of the herbal medicines for liver and kidney was also confirmed through blood tests. Conclusions : Hwangryeonagyo-tang and Mahwangbujasesin-tang helped relieve the itching and heat of eczema in currency. Therefore, it is believed that the proper use of thoes herbal medicine can be expected to have a useful effect on nummular eczema.

Keywords

References

  1. Choe YS, Lee SJ, Na GY, Kim DW. Clinical Study on Nummula Eczema. Annals of dermatology. 2005;43(8):1060-8.
  2. Jiamton S, Tangjaturonrusamee C, Kulthanan K. Clinical features and aggravating factors in nummular eczema in Thais. Asian Pac J Allergy Immunol. 2013;31(1):36-42.
  3. Jang IW, Han JM, Yoon HJ, Ko WS. A Case of Acute Multiple Nummular Eczema with Exudation. J Korean Med Ophthalmol Otolaryngol Dermatol. 2013;26(3):95-104. https://doi.org/10.6114/jkood.2013.26.3.095
  4. Chen J. The clinical observation on treating nummular eczema with the Spleen deficiency in accumulates dampness type by comfrey oil. Guangzhou University of Chinese Medicine. 2019:1-29.
  5. Trayes KP, Savage K, Studdiford JS. Annular Lesions: Diagnosis and Treatment. Am Fam Physician. 2018;98(5):283-91.
  6. Leung AK, Lam JM, Leong KF, Hon KL. Nummular Eczema: An Updated Review. Recent Pat Inflamm Allergy Drug Discov. 2020;14(2):146-55. https://doi.org/10.2174/22122710MTA59MDEa0
  7. Grennan D, Wang S. Steroid Side Effects. JAMA. 2019;322(3):282. https://doi.org/10.1001/jama.2019.8506
  8. Jea HK, Ahn JH, Hwang ML, Kim SY, Jung HA. Three Cases of Nummular Eczema Patients Treated with Cheongshimyeonjaeum Gagambang and Soyeom Pharmacopuncture. J Korean Med Ophthalmol Otolaryngol Dermatol. 2019;32(2):107-19. https://doi.org/10.6114/JKOOD.2019.32.2.107
  9. Kim HG, Kim JY, Kim SA, Lee JW, Lim SH. Review of Korean Medicine Treatments for Nummular Eczema in Korean Journals. J Korean Med Ophthalmol Otolaryngol Dermatol. 2019;32(4):116-29. https://doi.org/10.6114/JKOOD.2019.32.4.116
  10. Kang IJ, Shin MK, Haw CR. Patch Testing in Nummular Eczema: Comparison of Patch Test Results between Nummular Eczema and Atopic Dermatitis. Korean J Dermatol 2007;45(9):871-6.
  11. Kim HJ. Case review of Oriental Medical and Medical Literatures on Atopic Dermatitis patient with Nummular Eczema. The Journal of Oriental Medical Surgery, Ophthalmology & Otolaryngology. 2001;14(1):111-6.
  12. Reich A, Heisig M, Phan NQ, Taneda K, Takeuchi S, Furue M, Blome C, Augustin M et al. Visual Analogue Scale: Evalutation of the Instrument for the Assessment of Pruritus. Acta Derm Venereol. 2012;92: 449-581. https://doi.org/10.2340/00015555-1412
  13. Finlay AY, Khan GK. Dermatology Life Quality Index(DLQI) - a simple practical measure for routine clinical use. Clinical and Experimental Dermatology. 1994;19: 210-6. https://doi.org/10.1111/j.1365-2230.1994.tb01167.x
  14. Shin JM, Hyun JY. A Case Report of Soeumbyeong Acne Vulgaris Patient Treated with Osuyu-tang. The Journal of Korean Medicial Association of Clinical Sanghan-Geumgwe. 2013;5(1):93-100.
  15. Kim HK, Hong SU. The anti-inflammatory effects of Huang-Lyun(Coptidis Rhizoma, CR) on injured tissue after burn elicitation. J Korean Oriental Med. 2011;32(2):1-13.
  16. Yoon SB, Han HS, Lee YJ. Effect of Scutellariae Radix Extract on the Proinflammatory Mediators in Raw 264.7 Cells Induced by LPS. Kor. J. Herbology. 2011;26(2):75-81. https://doi.org/10.6116/KJH.2011.26.2.075
  17. Kim CH, Jeung JK. Study on Application of the Colla Corii Asini Blended Prescription form The Dongeuybogam. The Korean Journal of Oriental Medical Prescription. 2007;15(2):79-87.
  18. Lee JC, Park SY, Choi JH, Kim JH. Effects of Paeoniae radix alba(PRA) on Skin whitening and Elasticity using Melanoma cells. J Korean Med Ophthalmol Otolaryngol Dermatol. 2012;25(1):1-11. https://doi.org/10.6114/jkood.2012.25.1.001
  19. Yun HJ, Ha HY, Rho YB. A Case Report of Contact Dermatitis treated by Mahwang-tang based on Shanghanlun Provisions. Journal of Korean Medical Asscociation of Clinical Sanghan-Geumgwe. 2016;8(1):53-65.
  20. Kim WI. Experimental Study about Pathway of Aconiti Ciliare Tuber on Allergic Reaction of Inflammation. Korean Journal of Oriental Medicine. 2010;16(3):155-66.
  21. Choi CW, Oh MS. Study on Antioxidant and Anti-inflammatory Effects of Components of Mahwangbujaseshin-tang. J Korean Med Rehab. 2014;24(4):15-28.
  22. Chang MY. Huanglian Ejiao Decoction in treatment of stubborn dermatitis. Shanxi Journal of Traditional Chinese Medicine. 1986;4:47.
  23. Zhao D, Zhao H. A New Analysis on the Treatment of Acne Based on Syndrome. Journal of Zhejiang Chinese Medical University. 2020;10:949-52, 955.