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Prevalence of Defecation Disorders and their Symptoms is Comparable in Children and Young Adults: Cross-Sectional Study

  • Timmerman, Marjolijn E.W. (Department of Surgery, Division of Pediatric Surgery, University of Groningen, University Medical Center Groningen) ;
  • Trzpis, Monika (Department of Surgery, Anorectal Physiology Laboratory, University of Groningen, University Medical Center Groningen) ;
  • Broens, Paul M.A. (Department of Surgery, Division of Pediatric Surgery, University of Groningen, University Medical Center Groningen)
  • Received : 2020.05.24
  • Accepted : 2020.08.05
  • Published : 2021.01.15

Abstract

Purpose: We aimed to compare the prevalence rates and associated symptoms of constipation and fecal incontinence in children and young adults and evaluate how these patient groups cope with these disorders. Methods: A cross-sectional study was performed in which 212 children (8-17 years) and 149 young adults (18-29 years) from the general Dutch population completed a questionnaire about defecation disorders. Results: Constipation occurred in 15.6% of children and 22.8% of young adults (p=0.55), while the prevalence of fecal incontinence was comparable between groups (7%, p=0.91). The symptoms associated with constipation occurred as often in children as in young adults, while most fecal incontinence symptoms occurred more often in young adults. Approximately 43% of children had constipation for more than 5 years, while 26% of young adults experienced constipation since childhood. Only 27% of constipated children and 21% of constipated young adults received treatment (mostly laxatives). For fecal incontinence, 13% of children and 36% of young adults received treatment (mostly antidiarrheal medications or incontinence pads). Conclusion: In contrast to the general belief, the prevalence of defecation disorders and associated symptoms seem to be comparable in children and young adults. Only a few people with defecation disorders receive adequate treatment.

Keywords

References

  1. Rajindrajith S, Devanarayana NM, Crispus Perera BJ, Benninga MA. Childhood constipation as an emerging public health problem. World J Gastroenterol 2016;22:6864-75. https://doi.org/10.3748/wjg.v22.i30.6864
  2. Rouster AS, Karpinski AC, Silver D, Monagas J, Hyman PE. Functional gastrointestinal disorders dominate pediatric gastroenterology outpatient practice. J Pediatr Gastroenterol Nutr 2016;62:847-51. https://doi.org/10.1097/MPG.0000000000001023
  3. Bellman M. Studies on encopresis. Acta Paediatr Scand 1966;Suppl 170:1+.
  4. Abrahamian FP, Lloyd-Still JD. Chronic constipation in childhood: a longitudinal study of 186 patients. J Pediatr Gastroenterol Nutr 1984;3:460-7. https://doi.org/10.1097/00005176-198406000-00027
  5. Procter E, Loader P. A 6-year follow-up study of chronic constipation and soiling in a specialist paediatric service. Child Care Health Dev 2003;29:103-9. https://doi.org/10.1046/j.1365-2214.2003.00319.x
  6. Michaud L, Lamblin MD, Mairesse S, Turck D, Gottrand F. Outcome of functional constipation in childhood: a 10-year follow-up study. Clin Pediatr (Phila) 2009;48:26-31. https://doi.org/10.1177/0009922808320599
  7. Bongers ME, Benninga MA. Long-term follow-up and course of life in children with constipation. J Pediatr Gastroenterol Nutr 2011;53 Suppl 2:S55-6.
  8. van Ginkel R, Reitsma JB, Büller HA, van Wijk MP, Taminiau JA, Benninga MA. Childhood constipation: longitudinal follow-up beyond puberty. Gastroenterology 2003;125:357-63. https://doi.org/10.1016/S0016-5085(03)00888-6
  9. Filho HS, Mastroti RA, Klug WA. Quality-of-life assessment in children with fecal incontinence. Dis Colon Rectum 2015;58:463-8. https://doi.org/10.1097/DCR.0000000000000324
  10. Kovacic K, Sood MR, Mugie S, Di Lorenzo C, Nurko S, Heinz N, et al. A multicenter study on childhood constipation and fecal incontinence: effects on quality of life. J Pediatr 2015;166:1482-7.e1. https://doi.org/10.1016/j.jpeds.2015.03.016
  11. Ranasinghe N, Devanarayana NM, Benninga MA, van Dijk M, Rajindrajith S. Psychological maladjustment and quality of life in adolescents with constipation. Arch Dis Child 2017;102:268-73. https://doi.org/10.1136/archdischild-2016-310694
  12. McKenna C, Bartlett L, Ho YH. Fecal incontinence reduces quality of life more than you may think. Dis Colon Rectum 2017;60:e597-8. https://doi.org/10.1097/dcr.0000000000000832
  13. Vriesman MH, Rajindrajith S, Koppen IJN, van Etten-Jamaludin FS, van Dijk M, Devanarayana NM, et al. Quality of life in children with functional constipation: a systematic review and meta-analysis. J Pediatr 2019;214:141-50. https://doi.org/10.1016/j.jpeds.2019.06.059
  14. Park R, Mikami S, LeClair J, Bollom A, Lembo C, Sethi S, et al. Inpatient burden of childhood functional GI disorders in the USA: an analysis of national trends in the USA from 1997 to 2009. Neurogastroenterol Motil 2015;27:684-92. https://doi.org/10.1111/nmo.12542
  15. Sommers T, Corban C, Sengupta N, Jones M, Cheng V, Bollom A, et al. Emergency department burden of constipation in the United States from 2006 to 2011. Am J Gastroenterol 2015;110:572-9. https://doi.org/10.1038/ajg.2015.64
  16. Timmerman MEW, Trzpis M, Broens PMA. The problem of defecation disorders in children is underestimated and easily goes unrecognized: a cross-sectional study. Eur J Pediatr 2019;178:33-9. https://doi.org/10.1007/s00431-018-3243-6
  17. Meinds RJ, Timmerman MEW, van Meegdenburg MM, Trzpis M, Broens PMA. Reproducibility, feasibility and validity of the Groningen Defecation and Fecal Continence questionnaires. Scand J Gastroenterol 2018;53:790-6. https://doi.org/10.1080/00365521.2018.1465993
  18. Hyams JS, Di Lorenzo C, Saps M, Shulman RJ, Staiano A, van Tilburg M. Functional disorders: children and adolescents. Gastroenterology 2016;150:1456-68.e2. https://doi.org/10.1053/j.gastro.2016.02.015
  19. Mearin F, Lacy BE, Chang L, Chey WD, Lembo AJ, Simren M, et al. Bowel disorders. Gastroenterology 2016;150:1393-407.e5. https://doi.org/10.1053/j.gastro.2016.02.031
  20. Rao SS, Bharucha AE, Chiarioni G, Felt-Bersma R, Knowles C, Malcolm A, et al. Functional anorectal disorders. Gastroenterology 2016;150:1430-42.e4. https://doi.org/10.1053/j.gastro.2016.02.009
  21. Koppen IJN, Vriesman MH, Saps M, Rajindrajith S, Shi X, van Etten-Jamaludin FS, et al. Prevalence of functional defecation disorders in children: a systematic review and meta-analysis. J Pediatr 2018;198:121-30.e6. https://doi.org/10.1016/j.jpeds.2018.02.029
  22. Nelson RL. Epidemiology of fecal incontinence. Gastroenterology 2004;126(Suppl 1):S3-7. https://doi.org/10.1053/j.gastro.2003.10.010
  23. Chanpong A, Osatakul S. Laxative choice and treatment outcomes in childhood constipation: clinical data in a longitudinal retrospective study. Pediatr Gastroenterol Hepatol Nutr 2018;21:101-10. https://doi.org/10.5223/pghn.2018.21.2.101
  24. Lee G, Son JS, Bae SH. Clinical features of severely constipated children: comparison of infrequent bowel movement and fecal soiling groups. Pediatr Gastroenterol Hepatol Nutr 2020;23:26-34. https://doi.org/10.5223/pghn.2020.23.1.26
  25. Nurko S, Scott SM. Coexistence of constipation and incontinence in children and adults. Best Pract Res Clin Gastroenterol 2011;25:29-41. https://doi.org/10.1016/j.bpg.2010.12.002
  26. Rajindrajith S, Devanarayana NM, Benninga MA. Children and adolescents with chronic constipation: how many seek healthcare and what determines it? J Trop Pediatr 2012;58:280-5. https://doi.org/10.1093/tropej/fmr096
  27. Choung RS, Locke GR, Schleck CD, Ziegenfuss JY, Beebe TJ, Zinsmeister AR, et al. A low response rate does not necessarily indicate non-response bias in gastroenterology survey research: a population-based study. J Public Health 2013;21:87-95. https://doi.org/10.1007/s10389-012-0513-z