Acknowledgement
The authors would like to thank Yubin Song (Kyungpook National University, the Republic of Korea) for their assistance with data collection.
References
- Aurich C, Sieme H, Schlote S. 1994. Involvement of endogenous opioids in the regulation of LH and testosterone release in the male horse. J. Reprod. Fertil. 102:327-336. https://doi.org/10.1530/jrf.0.1020327
- Choi Y and Yoon M. 2021. The expression of androstenone receptor (OR7D4) in vomeronasal organ and olfactory epithelium of horses. Domest. Anim. Endocrinol. 74:106535. https://doi.org/10.1016/j.domaniend.2020.106535
- Clay CM, Squires EL, Nett TM. 1988. Influences of season and artificial photoperiod on stallions: luteinizing hormone follicle-stimulating hormone and testosterone. J. Anim. Sci. 66:1246-1255. https://doi.org/10.2527/jas1988.6651246x
- Dhakal P, Tsunoda N, Nakai R, Kitaura T, Harada T, Ito M, Nagaoka K, Toishi Y, Taniyama H, Taya K. 2011. Annual changes in day-length, temperature, and circulating reproductive hormones in Thoroughbred stallions and geldings. J. Equine Sci. 22:29-36. https://doi.org/10.1294/jes.22.29
- Djureinovic D, Fagerberg L, Hallstrom B, Danielsson A, Lindskog C, Ponten F. 2014. The human testis-specific proteome defined by transcriptomics and antibody-based profiling. Mol. Hum. Reprod. 20:476-488. https://doi.org/10.1093/molehr/gau018
- Drutel G, Arrang JM, Diaz J, Wisnewsky C, Schwartz JC. 1995. Cloning of OL1, a putative olfactory receptor and its expression in the developing rat heart. Recept. Channels 3:33-40.
- Firestein S. 2001. How the olfactory system makes sense of scents. Nature 413:211-218. https://doi.org/10.1038/35093026
- Fleischer J, Strotmann J. 2009. Mammalian olfactory receptors. Front. Cell. Neurosci. 3:9. https://doi.org/10.3389/neuro.03.009.2009
- Fukuda N, Yomogida K, Touhara K. 2004. Functional characterization of a mouse testicular olfactory receptor and its role in chemosensing and in regulation of sperm motility. J. Cell Sci. 117:5835-5845. https://doi.org/10.1242/jcs.01507
- Goto T, Monk M. 2001. Expression of a testis-specific member of the olfactory receptor gene family in human primordial germ cells. Mol. Hum. Reprod. 7:553-558. https://doi.org/10.1093/molehr/7.6.553
- Griffin CA, Pavlath GK. 2009. MOR23 promotes muscle regeneration and regulates cell adhesion and migration. Dev. Cell 17:649-661. https://doi.org/10.1016/j.devcel.2009.09.004
- Hwang JC, Kim HD, Park BJ, Jeon RH, Baek SM, Lee SW, Bae SG. , Yun SH, Park JK, Kwon YS, Kim SJ, Lee WJ. 2021. Immobilization stress increased cytochrome P450 1A2 (CYP1A2) expression in the ovary of rat. J. Anim. Reprod. Biotechnol. 36:9-16. https://doi.org/10.12750/JARB.36.1.9
- Itakura S, Ohno K, Ueki T, Kanayama N. 2006. Expression of Golf in the rat placenta: possible implication in olfactory receptor transduction. Placenta 27:103-108. https://doi.org/10.1016/j.placenta.2004.12.006
- Jung H, Yoon M. 2014. UTF1, a putative marker for spermatogonial stem cells in stallions. PLoS One 9:e108825. https://doi.org/10.1371/journal.pone.0108825
- Kim HR, Han RX, Kim MY, Diao Y, Jin DI. 2009. Protein expression of mouse uterus in post-implantation. Reprod. Dev. Biol. 33:237-242.
- Kim NY, Chae HS, Baek KS, Cho IC, Jung YH, Woo JH, Park SH, Kim JH, Yang YH. 2015. A study on the changes of coat color-related genes according to generational changes in Jeju horses. J. Emb. Trans. 30:183-188. https://doi.org/10.12750/JET.2015.30.3.183
- Milardi D, Colussi C, Grande G, Vincenzoni F, Pierconti F, Mancini F, Baroni S, Castagnola M, Pontecorvi A. 2018. Olfactory receptors in semen and in the male tract: from proteome to proteins. Front. Endocrinol. (Lausanne) 8:379. https://doi.org/10.3389/fendo.2017.00379
- Moe M, Lien S, Bendixen C, Hedegaard J, Hornshoj H, Berget I, Grindflek E. 2008. Gene expression profiles in liver of pigs with extreme high and low levels of androstenone. BMC Vet. Res. 4:29. https://doi.org/10.1186/1746-6148-4-29
- Mombaerts P. 1999. Molecular biology of odorant receptors in vertebrates. Annu. Rev. Neurosci. 22:487-509. https://doi.org/10.1146/annurev.neuro.22.1.487
- Neuhaus EM, Zhang W, Gelis L, Deng Y, Hatt H. 2009. Activation of an olfactory receptor inhibits proliferation of prostate cancer cells. J. Biol. Chem. 284:16218-16225. https://doi.org/10.1074/jbc.M109.012096
- Park HJ, Kim JW, Park JY, Yang SG, Jung JM, Koo DB. 2017. Ganglioside GD1a activates the phosphorylation of EGFR in porcine oocytes maturation in vitro. J. Emb. Trans. 32:17-24. https://doi.org/10.12750/JET.2017.32.1.17
- Robic A, Le Mignon G, Feve K, Riquet J. 2011. New investigations around CYP11A1 and its possible involvement in an androstenone QTL characterised in Large White pigs. Genet. Sel. Evol. 43:15. https://doi.org/10.1186/1297-9686-43-15
- Sinclair PA, Squires EJ, Renaud R. 2005. Synthesis of free and sulphoconjugated 16-androstene steroids by the Leydig cells of the mature domestic boar. J. Steroid Biochem. Mol. Biol. 96:217-228. https://doi.org/10.1016/j.jsbmb.2005.02.017
- Spehr M, Gisselmann G, Poplawski A, Riffell JA, Wetzel CH, Hatt H. 2003. Identification of a testicular odorant receptor mediating human sperm chemotaxis. Science 299:2054-2058. https://doi.org/10.1126/science.1080376
- Spehr M, Schwane K, Riffell JA, Barbour J, Zimmer RK, Hatt H. 2004. Particulate adenylate cyclase plays a key role in human sperm olfactory receptor-mediated chemotaxis. J. Biol. Chem. 279:40194-40203. https://doi.org/10.1074/jbc.M403913200
- Steiger SS, Kempenaers B. 2008. Detection of olfactory receptor transcripts in bird testes. J. Hered. 99:624-628. https://doi.org/10.1093/jhered/esn051
- Vanderhaeghen P, Schurmans S, Parmentier M. 1997a. Molecular cloning and chromosomal mapping of olfactory receptor genes expressed in the male germ line: evidence for their wide distribution in the human genome. Biochem. Biophys. Res. Commun. 237:283-287. https://doi.org/10.1006/bbrc.1997.7043
- Vanderhaeghen P, Schurmans S, Parmentier M. 1997b. Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species. Genomics 39:239-246. https://doi.org/10.1006/geno.1996.4490
- Weber M, Pehl U, Strotmann J. 2002. Olfactory receptor expressed in ganglia of the autonomic nervous system. J. Neurosci. Res. 68:176-184. https://doi.org/10.1002/jnr.10164
- Zamaratskaia G and Squires EJ. 2009. Biochemical, nutritional and genetic effects on boar taint in entire male pigs. Animal 3:1508-1521. https://doi.org/10.1017/s1751731108003674