A Case of Psychogenic Non Epileptic Seizure Patient Complaining Generalized Tonic-Clonic Seizures Treated with Combined Korean Medical Treatment

강직을 동반한 전신 발작을 호소하는 심인성 비간질성 발작 환자에 대한 복합 한의치험 1례

  • Lee, Seong Wook (Dept. of Clinical Korean Medicine, Graduate school, Kyung-Hee University) ;
  • Lee, Hyun-Ku (Dept. of Clinical Korean Medicine, Graduate school, Kyung-Hee University) ;
  • Bae, In Hu (Dept. of Clinical Korean Medicine, Graduate school, Kyung-Hee University) ;
  • Cho, Ki-Ho (Dept. of Cardiology and Neurology, College of Korean medicine, Kyung-Hee University) ;
  • Moon, Sang-Kwan (Dept. of Cardiology and Neurology, College of Korean medicine, Kyung-Hee University) ;
  • Jung, Woo-Sang (Dept. of Cardiology and Neurology, College of Korean medicine, Kyung-Hee University) ;
  • Kwon, Seungwon (Dept. of Cardiology and Neurology, College of Korean medicine, Kyung-Hee University) ;
  • Jin, Chul (Dept. of Cardiology and Neurology, College of Korean medicine, Kyung-Hee University)
  • 이성욱 (경희대학교 대학원 임상한의학과) ;
  • 이현규 (경희대학교 대학원 임상한의학과) ;
  • 배인후 (경희대학교 대학원 임상한의학과) ;
  • 조기호 (경희대학교 한의과대학 순환신경내과학교실) ;
  • 문상관 (경희대학교 한의과대학 순환신경내과학교실) ;
  • 정우상 (경희대학교 한의과대학 순환신경내과학교실) ;
  • 권승원 (경희대학교 한의과대학 순환신경내과학교실) ;
  • 진철 (경희대학교 한의과대학 순환신경내과학교실)
  • Published : 2021.12.01

Abstract

Psychogenic Non Epileptic Seizure (PNES) refers to a case in which symptoms are similar to epileptic seizures (ES), but ES do not appear in EEG and temporary abnormalities caused by physical diseases are also excluded. Psychotherapy and pharmacotherapy are most commonly used, but standard treatment for PNES has not been established and there is no alternative treatment available in the case of patients those treatments are not applied. We herein report a case of 46 year old male diagnosed with PNES who suffered from generalized tonic-clonic seizures. The patient underwent korean medical treatment by acupuncture and herbal medicine. The clinical symptom was evaluated by assessing occurrence frequency, number of seizures per 28 days. Compared to the period without korean medical treatment, the number of seizures decreased during the treatment period. The present case report suggested that korean medical treatment could be an effective option for those PNES patients complaining generalized tonic-clonic seizures.

Keywords

References

  1. Maria Oto, Markus Reuber. Psychogenic non-epileptic seizures: aetiology, diagnosis and management. Advances in Psychiatric Treatment. 2014;20(1);13-22 https://doi.org/10.1192/apt.bp.113.011171
  2. Kotsopoulos IA, de Krom MC, Kessels FG, et al. The diagnosis of epileptic and non-epileptic seizures. Epilepsy Research. 2003;57(1);59-67 https://doi.org/10.1016/j.eplepsyres.2003.10.014
  3. W. Curt LaFrance Jr, Markus Reuber, Laura H. Goldstein. Management of psychogenic nonepileptic seizures. Epilepsia. 2013;54(1);53-67 https://doi.org/10.1111/epi.12106
  4. W. Curt LaFrance Jr, Markus Reuber, Laura H. Goldstein. Management of psychogenic nonepileptic seizures. Epilepsia. 2013;54(1);53-67 https://doi.org/10.1111/epi.12106
  5. Edward Maa, Matthew Applegate, Angela Keniston. Auricular acupuncture for the treatment of nonepileptic seizures: A pilot study. Epilepsy & Behavior. 2020;111
  6. Chikako Uchida, Hideaki Waki, Yoichi Minakawa, et al. Evaluation of Autonomic Nervous System Function Using Heart Rate Variability Analysis During Transient Heart Rate Reduction Caused by Acupuncture. Med Acupunct. 2018. 30(2):89-95 https://doi.org/10.1089/acu.2017.1266
  7. Cianci V, Ferlazzo E, Condino F, et al. Rating scale for psychogenic nonepileptic seizures: scale development and clinimetric testing. Epilepsy Behav. 2011;21(2):128-31. https://doi.org/10.1016/j.yebeh.2011.03.025
  8. 장은영, 정세미나, 주은연 등. 뇌전증 및 정신성 발작 환자의 MMPI 프로파일 비교. J Korean Neurol Assoc. 2016;34(2):105-111. https://doi.org/10.17340/jkna.2016.2.3
  9. Bodde NM, Brooks JL, Baker GA, et al. Psychogenic non-epileptic seizures-diagnostic issues: a critical review. Clin Neurol Neurosurg. 2009;111;1-9 https://doi.org/10.1016/j.clineuro.2008.09.028
  10. Ali A. Asadi-Pooya, Michael R. Sperling. Epidemiology of psychogenic nonepileptic seizures. Epilepsy&Behavior. 2015;46;60-65 https://doi.org/10.1016/j.yebeh.2015.03.015
  11. Roderick Duncan. Psychogenic nonepileptic seizures: diagnosis and initial management. Expert Rev Neurother. 2010;10(12);1803-1809 https://doi.org/10.1586/ern.10.171
  12. Mia Tuft, Hilde Nordahl Karterud, Antonia Villagran, et al. Treatment for psychogenic non-epileptic seizures. Tidsskr Nor Legeforen. 2015;135:1449-1451 https://doi.org/10.4045/tidsskr.14.1361
  13. Lee IH, Lee SR, Kim MJ, et al. Two Case Reports of Bedridden Patients with VRE colonization treated with Bojungiki-tang. The Journal of Internal Korean Medicine 2014: 344-8.
  14. Fukumura N, Yamamoto H, Kitahara M, et al. Hochuekkito Reduced the Incidence of Inflammatory Complications in Patients with Sequelae of Cerebrovascular Disease in Convalescent Rehabilitation Wards:A Randomized Multicenter Study. The Japanese Journal of Rehabilitation Medicine 2017:54(4):303-14 https://doi.org/10.2490/jjrmc.54.303
  15. Heo J. Dongeuibogam 1 Seoul: Namsandang: 2014. p. 215-6.
  16. Cho KH, Kin TH, Jin C, et al. The Literary Trends of Herbal Prescription Ukgan-san and its Application in Modern Traditional Korean Medicine. J Korean Med 2018;39(3):17-27. https://doi.org/10.13048/jkm.18021
  17. Hyun WC, Lee SR. Studies on the Effect of AntiConvulsion and Analgesic by Ukgansan and Ukgansangami. J of Oriental Neuropsychiatry 1994;5(1):69-79.
  18. Jang JH, Jung KS, Kim JS, et al. Potential Application of Yokukansan as a Remedy for Parkinson's Disease. Evidence-Based Complementary and Alternative Medicine. 2018.
  19. Lee SH, Shin SW, Kim TH, et al. Safety, effectiveness, and Economic Evaluation of an Herbal Medicine, Ukgansangajinpibanha Granule, in Children with Autism Spectrum Disorder:A Study Protocol for a Prospective, Multicenter, Randomized, Double-blined, Placebo-controlled, Parallel-group Clinical Trial. Trials 2019;20:434-44. https://doi.org/10.1186/s13063-019-3537-7
  20. Chikako Uchida, Hideaki Waki, Yoichi Minakawa, et al. Evaluation of Autonomic Nervous System Function Using Heart Rate Variability Analysis During Transient Heart Rate Reduction Caused by Acupuncture. Med Acupunct. 2018. 30(2):89-95 https://doi.org/10.1089/acu.2017.1266
  21. Edward Maa, Matthew Applegate, Angela Keniston. Auricular acupuncture for the treatment of nonepileptic seizures: A pilot study. Epilepsy & Behavior. 2020;111