Childhood Kidney Diseases

Korean Society of Pediatric Nephrology (대한소아신장학회)
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Extraskeletal Calcifications in Children with Maintenance Peritoneal Dialysis

  • Oh, Eunhye (Department of Pediatrics, Seoul National University Children's Hospital) ;
  • Min, Jeesu (Department of Pediatrics, Seoul National University Children's Hospital) ;
  • Lim, Seon Hee (Department of Pediatrics, Uijeongbu Eulji Medical Center) ;
  • Kim, Ji Hyun (Department of Pediatrics, Seoul National University Bundang Hospital) ;
  • Ha, Il-Soo (Department of Pediatrics, Seoul National University Children's Hospital) ;
  • Kang, Hee Gyung (Department of Pediatrics, Seoul National University Children's Hospital) ;
  • Ahn, Yo Han (Department of Pediatrics, Seoul National University Children's Hospital)
  • Received : 2021.08.25
  • Accepted : 2021.10.06
  • Published : 2021.12.31
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Abstract

Chronic kidney disease (CKD)-mineral and bone disorder (CKD-MBD) is a common complication of CKD, often accompanied by extra-skeletal calcification in adult patients. As increased vascular calcification is predicted to increase cardiovascular mortality and morbidity, the revised Kidney Disease: Improving Global Outcomes guidelines recommend avoiding calcium-containing phosphate chelators. However, extra-skeletal calcification is less commonly noticed in pediatric patients. Here, we report our experience of such a complication in pediatric patients receiving maintenance peritoneal dialysis. Extra-skeletal calcification was noticed at the corneas, pelvic cavity, and soft tissues of the lower leg in 4 out of 32 patients on maintenance peritoneal dialysis. These patients experienced the aggravation of extra-skeletal calcifications during peritoneal dialysis, and 2 of them underwent excisional operations. It is required to monitor extra-skeletal calcifications in children on kidney replacement therapy.

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References

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