Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Simultaneous Determination of Four Compounds from Cercidiphyllum japonicum Using HPLC-UV Analysis

  • Kang, Jeongyeon (College of Pharmacy, Kangwon National University) ;
  • Jang, Hyeon Seok (College of Pharmacy, Kangwon National University) ;
  • Kim, Ju Yeol (College of Pharmacy, Kangwon National University) ;
  • Lee, Min Sung (Wild plants and Seeds Conservation Department, Baekdudaegan National Arboretum) ;
  • Bae, Young Soo (College of Forest and Environmental Sciences, Kangwon National University) ;
  • Kwon, Yongsoo (College of Pharmacy, Kangwon National University) ;
  • Yang, Heejung (College of Pharmacy, Kangwon National University)
  • Received : 2021.11.22
  • Accepted : 2021.12.22
  • Published : 2021.12.31
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Abstract

Cercidiphyllum japonicum is being used for the treatment of obesity and liver fibrosis in Korean local clinics. In the present study, we tried to develop an analytical methodology for the determination of the chemical markers of Cercidiphyllum japonicum. Four chemicals, maltol (1), chlorogenic acid (2), quercetin (3), and avicularin (4), were selected for method validation, and the analytical conditions were optimized and validated using high-performance liquid chromatography coupled with an ultraviolet detector (HPLC-UV). Additionally, the seasonal variations of four markers were monitored every month for six months. The contents of four chemicals markers were most detected in a sample collected in June.

Keywords

Acknowledgement

This work was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) grant funded by the Korean government (MEST) (NRF- 2021R1C1C1011857).

References

  1. Nakanishi, A.; Goto, S.; Sumiyoshi, C.; Isagi, Y. Ecol. Evol. 2021, 11, 7754-7767. https://doi.org/10.1002/ece3.7609
  2. Zhu, S.; Chen, J.; Zhao, J.; Comes, H. P.; Li, P.; Fu, C.; Xie, X.; Lu, R.; Xu, W.; Feng, Y.; Ye, W.; Sakaguchi, S.; Isagi, Y.; Li, L.; Lascoux, M.; Qiu, Y. New Phytol. 2020, 228, 1674-1689. https://doi.org/10.1111/nph.16798
  3. Lee, T. S.; Ryu, W. G.; Bae, Y. S. J. Korean Wood Sci. Technol. 2015, 43, 238-247. https://doi.org/10.5658/WOOD.2015.43.2.238
  4. Min, H. J.; Lee, M. S.; Kim, Y. K.; Bae, Y. S. J. Korean Wood Sci. Technol. 2017, 45, 250-257. https://doi.org/10.5658/WOOD.2017.45.3.250
  5. Yi, B. H.; Kim, D. H. Korean J. Food Sci. Technol. 1982, 14, 265-270.
  6. Yasumoto, E.; Nakano, K.; Nakayachi, T.; Morshed, S. R. M.; Hashimoto, K.; Kikuchi, H.; Nishikawa, H.; Kawase, M.; Sakagami, H. Anticancer Res. 2004, 24, 755-762.
  7. Naveed, M.; Hejazi, V.; Abbas, M.; Kamboh, A. A.; Khan, G. J.; Shumzaid, M.; Ahmad, F.; Babazadeh, D.; FangFang, X.; Modarresi- Ghazani, F.; WenHua, L.; XiaoHui, Z. Biomed. Pharmacother. 2018, 97, 67-74. https://doi.org/10.1016/j.biopha.2017.10.064
  8. Kschonsek, J.; Wolfram, T.; Stockl, A.; Bohm, V. Antioxidants 2018, 7, 20. https://doi.org/10.3390/antiox7010020
  9. Shen, Z.; Xu, Y.; Jiang, X.; Wang, Z.; Guo, Y.; Pan, W.; Hou, J. Med. Sci. Monit, 2019, 25, 2777-2784. https://doi.org/10.12659/msm.912401
  10. Wang, H.; Du, Y. J.; Song, H. C. Food Chem. 2010, 123, 6-13. https://doi.org/10.1016/j.foodchem.2010.03.088
  11. Korea Meteorological Administration. Annual Climatological Report 2015; Korea Meteorological Administration: Korea, 2015, p 45.
  12. Tiefel, P.; Berger, R. G. J. Sci. Food Agric. 1993, 63, 59-61. https://doi.org/10.1002/jsfa.2740630110
  13. Gobbo-Neto, L.; Bauermeister, A.; Sakamoto, H. T.; Gouvea, D. R.; Lopes, J. C.; Lopes, N. P. J. Braz. Chem. Soc. 2017, 28, 2382-2390.