Korean Journal of Veterinary Research (대한수의학회지)

The Korean Society of Veterinary Science (대한수의학회)
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Prevalence and pathologic study of porcine epidemic diarrhea in Jeju

제주도의 돼지유행성설사 발생 상황과 병리학적 고찰

  • Kim, Hyeon-Ju (Jeju Self-Governing Provincial Veterinary Research Institute) ;
  • Yang, Hyoung-Seok (Jeju Self-Governing Provincial Veterinary Research Institute) ;
  • Kang, Sang Chul (Optipharm Inc.) ;
  • Kim, Jae-Hoon (College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University)
  • 김현주 (제주특별자치도 동물위생시험소) ;
  • 양형석 (제주특별자치도 동물위생시험소) ;
  • 강상철 (옵티팜) ;
  • 김재훈 (제주대학교 수의과대학 및 수의과학연구소)
  • Received : 2021.06.09
  • Accepted : 2021.08.02
  • Published : 2021.12.31
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Abstract

From April 2014 to September 2015, 153 piglets from 52 farms in Jeju were diagnosed with porcine epidemic diarrhea (PED). The major PED cases were focused on suckling piglets (144 piglets, 94.1%), particularly in 1-7-day-old piglets. Histopathologically, severe villous atrophy was observed in the small intestine, especially in the jejunum and ileum. The mean villous height to crypt depth ratios of the jejunum and ileum were 1.4:1 and 1.5:1, respectively. The major histopathologic findings of the small intestine were cytoplasmic vacuolation, cuboidalization, squamation, and exfoliation of the mucosal enterocytes in the villi. The cytoplasmic vacuolations in the enterocytes were the most prevalent lesions in the small intestine and were more severe in the ileum than in the jejunum. According to immunohistochemistry methods, the PED virus (PEDV) antigens were presented in the cytoplasms of the enterocytes, and were distributed more prevalently in the ileum than in the jejunum. PEDV antigens were also detected in the colon of 26 piglets (19.5%). Sequence comparison and phylogenetic analysis indicated that 12 PEDV had more than a 98.9% homology with each other. These PEDV strains were highly homologous with the genogroup 2 North American group.

Keywords

Acknowledgement

본 논문은 농림축산검역본부 학술연구용역과제(Z-1543083-2017-18-01) 연구비를 지원받아 수행되었으며, 이에 감사드립니다.

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