Korean Journal of Head & Neck Oncology (대한두경부종양학회지)

The Korean Society for Head and Neck Oncology (대한두경부종양학회)
권호 표지
DOI QR코드

DOI QR Code

A Case of Epithelial-Myoepithelial Carcinoma of Parotid Gland and Analysis of 33 Cases Reported in Korea

이하선의 상피-근상피 암종 1례와 국내에 보고된 33건의 증례 분석

  • Kim, Ji Won (Department of Otolaryngology-Head and Neck Surgery, National Medical Center) ;
  • Kim, Min Soo (Department of Otolaryngology-Head and Neck Surgery, National Medical Center) ;
  • Kim, Bo Sung (Department of Pathology, Green Cross Laboratories) ;
  • Kim, Seong Dong (Department of Otolaryngology-Head and Neck Surgery, National Medical Center)
  • 김지원 (국립중앙의료원 이비인후-두경부외과) ;
  • 김민수 (국립중앙의료원 이비인후-두경부외과) ;
  • 김보성 (GC녹십자의료재단 병리학부) ;
  • 김성동 (국립중앙의료원 이비인후-두경부외과)
  • Received : 2021.04.20
  • Accepted : 2021.07.02
  • Published : 2021.11.30
Download PDF
⟨ Previous Next ⟩

Abstract

Epithelial-myoepithelial carcinoma is rare, low-grade malignant neoplasm that compromises approximately 1% of all salivary gland neoplasms. We reported a 68-year-old woman with epithelial-myoepithelial carcinoma in the parotid gland. We analyzed demographic and clinicopathological characteristics of salivary gland epithelial-myoepithelial carcinoma which has been reported in 33 cases in Korea from 1992 to 2017, and compared this result to overseas retrospective cohort studies. There was no significance in terms of mean age at diagnosis, the predominance of females, low frequency in regional lymph nodes, and distant metastasis between the two groups. However, T classification and AJCC stage at diagnosis in domestic cases are more advanced than those of overseas cases. Although the recurrence rate in domestic cases has been reported lower than that of overseas, further study may be needed considering that the follow-up period after treatment is short in domestic cases.

Keywords

References

  1. Alejandro V, Tapan DP, Christine MD, Rami YA, William F, Soly B, et al. Epithelial-myoepithelial carcinoma of the salivary glands : An analysis of 246 cases. Otolaryngol Head Neck Surg. 2015;153:569-574. https://doi.org/10.1177/0194599815594788
  2. Mitchell R. Epitheilal-myoepithelial carcinoma: A population based survival analysis. BMC Ear, Nose and Throat Disorders. 2018;18:1-10. https://doi.org/10.1186/s12901-018-0051-6
  3. Seethala RR, Barnes EL, Hunt JL. Epithelial-myoepithelial carcinoma: A review of the clinicopathologic spectrum and immunophenotypic characteristics in 61 tumors of the salivary glands and upper aerodigestive tract. Am J Surg Pathol. 2007;31:44-57. https://doi.org/10.1097/01.pas.0000213314.74423.d8
  4. Lee JW, Choi JJ, Kim MH, Kim YS. Epithelial-myoepithelial carcinoma of parotid glands: 3 cases misdiagnosed as pleomorphic adenoma. Korean J Head Neck Oncol. 2017;33:43-47.
  5. Kwack BG, Baek MK, Kim DY, Woo JH. A case of epithelial-myoepithelial carcinoma originating from minor salivary gland of tongue base. Korean J Otorhinolaryngol-Head Neck Surg. 2014;57:255-258. https://doi.org/10.3342/kjorl-hns.2014.57.4.255
  6. Lee JG, Cho HP, Lee JK, Park JH. A case of epithelial-myoepithelial carcinoma in sublingual gland. J Clinical Otolaryngol. 2014;25:75-79.
  7. Jin SM, Ryu HH, Ryu SH, Shin DY, Hwang HS, Kim CH, et al. Epithelial-myoepithelial carcinoma on the superficial lobe of the parotid gland : A case report. J Korean Assoc Oral Maxillofac Surg. 2011;37:505-509. https://doi.org/10.5125/jkaoms.2011.37.6.505
  8. Pae WS, Roh SG, Lee NH, Yang KM, Kang MJ. Epithelial-myoepithelial carcinoma of the parotid gland: A case report. J Korean Soc Plast Reconstr Surg. 2011;38:501-504.
  9. Han KH, Yoon HJ, Hong SD, Lee JI, Hong SP. Epithelial-myoepithelial carcinoma of the salivary gland : Report of 4 cases and review of the literature. Kor J Oral Maxillofac Pathol. 2009;33:233-238.
  10. Yoon BN, Lee BJ, Kong SK. A case of epithelial-myoepithelial carcinoma of parotid gland involving facial nerve: Facial nerve reconstruction with intratemporal nerve grafting. J Clinical Otolaryngol. 2006;17:294-299.
  11. You TM, Jung YS, Kim MK, Cha IH, Kim J, Kim HJ. Epithelial-myoepithelial carcinoma of the parotid gland: A case report. Kor J Oral Maxillofac Surg. 2003;29:131-134.
  12. Choi DJ, Suh JH, Cheong WY, Park CS, Choi EC, Kim HJ, et al. Epithelial-myoepithelial carcinoma of the salivary gland: Review of the literature with report of four cases. Korean J Head Neck Oncol. 2001;17:238-241.
  13. Kim KH, Sung MW, Lee CH, Rhee CS, Yun JB, Mo JH, et al. Epithelial-myoepithelial carcinoma of the salivary glands: Clinical aspects and treatment outcome. Korean J Otorhinolaryngol-Head Neck Surg. 1997;40:1593-1599.
  14. Kim K. Epithelial-myoepithelial carcinoma of the parotid gland: Report of a case and review of the literature. Ajou Med J. 1996;1:518-522.
  15. Lee SD, Chung DH, Park SH, Kim CW, Chi JG. Epithelial-myoepithelial carcinoma of intercalated duct of parotid gland. Korean J Pathol. 1992;26:76-81.