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Prevalence and Current Status of Dental Treatment for Amelogenesis Imperfecta and Dentinogenesis Imperfecta using National Health Insurance Database

국민건강보험공단 자료를 이용한 법랑질 형성부전증과 상아질 형성부전증의 유병률과 치과치료의 현황

  • Kim, Nawoon (Department of Pediatric Dentistry and Institute of Oral Bioscience, School of Dentistry, Jeonbuk National University) ;
  • Lee, Daewoo (Department of Pediatric Dentistry and Institute of Oral Bioscience, School of Dentistry, Jeonbuk National University) ;
  • Kim, Jaegon (Department of Pediatric Dentistry and Institute of Oral Bioscience, School of Dentistry, Jeonbuk National University) ;
  • Lim, Hyungbin (Department of Pediatric Dentistry and Institute of Oral Bioscience, School of Dentistry, Jeonbuk National University) ;
  • Yang, Yeonmi (Department of Pediatric Dentistry and Institute of Oral Bioscience, School of Dentistry, Jeonbuk National University)
  • 김나운 (전북대학교 치과대학 소아치과학교실 및 구강생체과학연구소) ;
  • 이대우 (전북대학교 치과대학 소아치과학교실 및 구강생체과학연구소) ;
  • 김재곤 (전북대학교 치과대학 소아치과학교실 및 구강생체과학연구소) ;
  • 임형빈 (전북대학교 치과대학 소아치과학교실 및 구강생체과학연구소) ;
  • 양연미 (전북대학교 치과대학 소아치과학교실 및 구강생체과학연구소)
  • Received : 2021.04.08
  • Accepted : 2021.05.27
  • Published : 2021.11.30

Abstract

The aim of this study was to determine the prevalence and incidence and evaluate the current status of dental treatment of Amelogenesis imperfecta (AI) and Dentinogenesis imperfecta (DI) in South Korea. The data was based on National Health Insurance Service (NHIS)-National Sample Cohort Database (2002 - 2015) and Jeonbuk National University (JBNU) Dental Hospital (2011 - 2020). The NHIS data analysis showed prevalence of AI and DI were 11.6 and 2.4 per 100,000 people, respectively. The annual incidence of AI and DI for 2013 - 2015 were 2.2 and 0.5 per 100,000. There were no statistically significant differences regarding the number of visits, the reimbursable cost among AI, DI patients and others. In the patient analysis of the JBNU dental hospital, proportion of the reimbursable and non-reimbursable cost for AI patients were 12.1% and 87.9%, while DI patients accounted for 18.6% and 81.4%.

이 연구의 목적은 국내의 법랑질 형성부전(Amelogenesis imperfecta, AI)과 상아질 형성부전(Dentinogenesis imperfecta, DI) 환자의 유병률 및 발생률을 조사하고, 치과 치료의 현황을 파악하는 것이다.국민건강보험공단 자료 분석에서 AI와 DI의 유병률은 각각 100,000명당 11.6명, 2.4명이었으며, 2013년 - 2015년 연간 발생률은 각 각 100,000명당 2.2명, 0.5명이었다. 국민건강보험공단 자료에서 해당 환자들의 내원 횟수, 치료 비용은 대조군과 차이가 없었지만 전북대학교 치과병원 자료의 분석 결과 총 내원 횟수 중 비급여 진료만 시행한 횟수는 AI, DI 각각 46.2%, 42.9%를 차지하고 있었고, 총 치료 비용 중 비급여 비용이 AI, DI 각각 87.9%, 81.4%로 큰 비율을 차지하였다. 이 연구는 AI와 DI 환자의 국내 현황에 대해 분석하였으며, 이에 대한 검증을 위한 다기관의 협력 하에 이루어지는 추가 연구가 필요할 것으로 사료된다.

Keywords

References

  1. Witkop CJ Jr : Amelogenesis imperfecta, dentinogenesis imperfecta and dentin dysplasia revisited: problems in classification. J Oral Pathol, 17:547-553, 1988. https://doi.org/10.1111/j.1600-0714.1988.tb01332.x
  2. Backman B, Holm AK : Amelogenesis imperfecta: prevalence and incidence in a northern Swedish county. Community Dent Oral Epidemiol, 14:43-47, 1986. https://doi.org/10.1111/j.1600-0528.1986.tb01493.x
  3. Seow WK : Developmental defects of enamel and dentine: challenges for basic science research and clinical management. Aust Dent J, 59 Suppl 1:143-154, 2014. https://doi.org/10.1111/adj.12104
  4. Wright JT : The molecular etiologies and associated phenotypes of amelogenesis imperfecta. Am J Med Genet A, 140:2547-2555, 2006. https://doi.org/10.1002/ajmg.a.31358
  5. Shields ED, Bixler D, El Kafrawy AM : A proposed classification for heritable human dentine defects with a description of a new entity. Arch Oral Biol, 18:543-553, 1973. https://doi.org/10.1016/0003-9969(73)90075-7
  6. Kim JW, Simmer JP : Hereditary dentin defects. J Dent Res, 86:392-399, 2007. https://doi.org/10.1177/154405910708600502
  7. Maciejewska I, Chomik E : Hereditary dentine diseases resulting from mutations in DSPP gene. J Dent, 40:542-548, 2012. https://doi.org/10.1016/j.jdent.2012.04.004
  8. Koruyucu M, Bayram M, Tuna EB, et al. : Clinical findings and long-term managements of patients with amelogenesis imperfecta. Eur J Dent, 8:546-552, 2014. https://doi.org/10.4103/1305-7456.143640
  9. Bouvier D, Duprez JP, Bois D : Rehabilitation of young patients with amelogenesis imperfecta: a report of two cases. ASDC J Dent Child, 63:443-447, 1996.
  10. Gallusi G, Libonati A, Campanella V : SEM-morphology in dentinogenesis imperfecta type II: microscopic anatomy and efficacy of a dentine bonding system. Eur J Paediatr Dent, 7:9-17, 2006.
  11. Pousette Lundgren G, Dahllof G : Outcome of restorative treatment in young patients with amelogenesis imperfecta. a cross-sectional, retrospective study. J Dent, 42:1382-1389, 2014. https://doi.org/10.1016/j.jdent.2014.07.017
  12. Sapir S, Shapira J : Dentinogenesis imperfecta: an early treatment strategy. Pediatr Dent, 23:232-237, 2001.
  13. Coffield KD, Phillips C, Brady M, et al. : The psychosocial impact of developmental dental defects in people with hereditary amelogenesis imperfecta. J Am Dent Assoc, 136: 620-630, 2005. https://doi.org/10.14219/jada.archive.2005.0233
  14. Incici E, Matuliene G, Husler J, et al. : Cumulative costs for the prosthetic reconstructions and maintenance in young adult patients with birth defects affecting the formation of teeth. Clin Oral Implants Res, 20:715-721, 2009. https://doi.org/10.1111/j.1600-0501.2009.01711.x
  15. Pousette Lundgren G, Karsten A, Dahllof G : Oral healthrelated quality of life before and after crown therapy in young patients with amelogenesis imperfecta. Health Qual Life Outcomes, 13:197, 2015. https://doi.org/10.1186/s12955-015-0393-3
  16. Chosack A, Eidelman E, Wisotski I, et al. : Amelogenesis imperfecta among Israeli Jews and the description of a new type of local hypoplastic autosomal recessive amelogenesis imperfecta. Oral Surg Oral Med Oral Pathol, 47:148-156, 1979. https://doi.org/10.1016/0030-4220(79)90170-1
  17. Kim SK, Lee CH : A Study on Prevalence and Pattern of Dental Developmental Anormalies. Korean J OMP, 29:257-269, 2005.
  18. Lee JH, Son HG : A study on prevalence and pattern of dental anomalies. J Korean Acad Pediatr Dent, 23:429-449, 1996.
  19. Kim JW : Molecular genetic etiology of amelogenesis imperfecta. J Korean Acad Pediatr Dent, 35:181-185, 2008.
  20. Kim JW : Molecular pathophysiology of dentinogenesis imperfecta. J Korean Acad Pediatr Dent, 33:738-742, 2006.
  21. Locker D : Disparities in oral health-related quality of life in a population of Canadian children. Community Dent Oral Epidemiol, 35:348-356, 2007. https://doi.org/10.1111/j.1600-0528.2006.00323.x
  22. Paula JS, Leite IC, Almeida AB, et al. : The influence of oral health conditions, socioeconomic status and home environment factors on schoolchildren's self-perception of quality of life. Health Qual Life Outcomes, 10:6, 2012. https://doi.org/10.1186/1477-7525-10-6
  23. Piovesan C, Antunes JL, Guedes RS, et al. : Impact of socioeconomic and clinical factors on child oral health-related quality of life (COHRQoL). Qual Life Res, 19:1359-1366, 2010. https://doi.org/10.1007/s11136-010-9692-7
  24. Kumar S, Gupta S : The restoration of function and esthetics of a patient with amelogenesis imperfecta using a combination of orthodontic and prosthodontic treatment: a case report. J Contemp Dent Pract, 10:E079-085, 2009.
  25. Marquezin MC, Zancope BR, Pacheco LF, et al. : Aesthetic and functional rehabilitation of the primary dentition affected by amelogenesis imperfecta. Case Rep Dent, 2015: 790890, 2015. https://doi.org/10.1155/2015/790890
  26. Sabandal MM, Schafer E : Amelogenesis imperfecta: review of diagnostic findings and treatment concepts. Odontology, 104:245-256, 2016. https://doi.org/10.1007/s10266-016-0266-1
  27. Trentesaux T, Rousset MM, Dehaynin E, et al. : 15-year follow- up of a case of amelogenesis imperfecta: importance of psychological aspect and impact on quality of life. Eur Arch Paediatr Dent, 14:47-51, 2013. https://doi.org/10.1007/s40368-012-0008-1
  28. Ubaldini AL, Giorgi MC, Carvalho AB, et al. : Adhesive Restorations as An Esthetic Solution in Dentinogenesis Imperfecta. J Dent Child (Chic), 82:171-175, 2015.
  29. Lee J, Lee H, Son D, et al. : Effects of National Dental Screening on Dental Caries Experience, Treatment, and Cost in Children. J Korean Acad Pediatr Dent, 47:248-256, 2020. https://doi.org/10.5933/JKAPD.2020.47.3.248
  30. Lundgren GP, Dahllof G : Outcome of restorative treatment in young patients with amelogenesis imperfecta. a cross-sectional, retrospective study. J Dent, 42:1382-1389, 2014. https://doi.org/10.1016/j.jdent.2014.07.017