Korean Journal of Head & Neck Oncology (대한두경부종양학회지)

The Korean Society for Head and Neck Oncology (대한두경부종양학회)
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A Case of Parotid Metastasis from Sebaceous Carcinoma of the Eyelids

이하선으로 전이된 안검의 피지샘 암종 1예

  • Chae, Hee Sung (Department of Otorhinolaryngology-Head and Neck Surgery, Yonsei University Wonju College of Medicine) ;
  • Yang, Hui Joon (Department of Otorhinolaryngology-Head and Neck Surgery, Yonsei University Wonju College of Medicine) ;
  • Paik, Seung Won (Department of Otorhinolaryngology-Head and Neck Surgery, Yonsei University Wonju College of Medicine) ;
  • Kim, Ji-Hoon (Department of Otorhinolaryngology, National Health Insurance Service Ilsan Hospital)
  • 채희성 (연세대학교 원주의과대학 이비인후과학 교실) ;
  • 양희준 (연세대학교 원주의과대학 이비인후과학 교실) ;
  • 백승원 (연세대학교 원주의과대학 이비인후과학 교실) ;
  • 김지훈 (국민건강보험 일산병원 이비인후과)
  • Received : 2020.04.08
  • Accepted : 2020.07.28
  • Published : 2020.11.30
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Abstract

Sebaceous carcinoma is a relatively rare and aggressive malignant tumor. Periocular area (especially eyelid) is the most common lesion to occur, and the most common extraocular lesion is the parotid gland. Because the lesion also mimic other benign inflammatory diseases, this leads to delayed diagnosis or misdiagnosis. Here, we report a 58-year-old male patient who presented with a non-tender painless left parotid mass after wide excision of sebaceous carcinoma in the left eyelid two years ago. When he was diagnosed with sebaceous carcinoma of left eyelid, there was a small left parotid tumor on the computed tomography. But no further examination and treatment were performed. Two years later, physical examination revealed growing parotid tumor and multiple neck nodes on the left side. After radical parotidectomy and neck dissection, histological examination showed a sebaceous carcinoma and neck node metastasis. Considering the aggressiveness of sebaceous carcinoma, further evaluation for parotid glands should be considered when sebaceous carcinoma of the eyelid was discovered. Postoperative chemoradiotherapy was performed for disease control. Follow up after two years, and computed tomography showed no sign of recurrence.

Keywords

References

  1. Kaliki S, Ayyar A, Dave TV, Ali MJ, Mishra DK, Naik MN. Sebaceous gland carcinoma of the eyelid: clinicopathological features and outcome in Asian Indians. Eye (Lond). 2015;29:958-963. https://doi.org/10.1038/eye.2015.79
  2. Mighell AJ, Stassen LF, Soames JV. Sebaceous carcinoma of the parotid gland. Dentomaxillofac Radiol. 1996;25:51-53. https://doi.org/10.1259/dmfr.25.1.9084287
  3. Gnepp DR, Brannon R. Sebaceous neoplasms of salivary gland origin. Report of 21 cases. Cancer. 1984;53:2155-2170. https://doi.org/10.1002/1097-0142(19840515)53:10<2155::AID-CNCR2820531026>3.0.CO;2-F
  4. Dasgupta T, Wilson LD, Yu JB. A retrospective review of 1349 cases of sebaceous carcinoma. Cancer. 2009;115:158-165. https://doi.org/10.1002/cncr.23952
  5. Cook BE Jr, Bartley GB. Treatment options and future prospects for the management of eyelid malignancies: an evidence-based update. Ophthalmology. 2001;108:2088-2121. https://doi.org/10.1016/S0161-6420(01)00796-5
  6. Husain A, Blumenschein G, Esmaeli B. Treatment and outcomes for metastatic sebaceous cell carcinoma of the eyelid. Int J Dermatol. 2008;47:276-279. https://doi.org/10.1111/j.1365-4632.2008.03496.x
  7. Leibovitch I, Selva D, Huilgol S, Davis G, Dodd T, James CL. Intraepithelial sebaceous carcinoma of the eyelid misdiagnosed as Bowen's disease. J Cutan Pathol. 2006;33:303-308. https://doi.org/10.1111/j.0303-6987.2006.00423.x
  8. Shields JA, Demirci H, Marr BP, Eagle RC Jr, Shields CL. Sebaceous carcinoma of the ocular region: a review. Surv Ophthalmol. 2005;50:103-122. https://doi.org/10.1016/j.survophthal.2004.12.008
  9. Snow SN, Larson PO, Lucarelli MJ, Lemke BN, Madjar DD. Sebaceous carcinoma of the eyelids treated by mohs micrographic surgery: report of nine cases with review of the literature. Dermatol Surg. 2002;28:623-631. https://doi.org/10.1097/00042728-200207000-00023
  10. Kivela T, Asko-Seljavaara S, Pihkala U, Hovi L, Heikkonen J. Sebaceous carcinoma of the eyelid associated with retinoblastoma. Ophthalmology. 2001;108:1124-1128. https://doi.org/10.1016/S0161-6420(01)00555-3
  11. Stockl FA, Dolmetsch AM, Codere F, Burnier MN Jr. Sebaceous carcinoma of the eyelid in an immunocompromised patient with Muir-Torre syndrome. Can J Ophthalmol. 1995;30:324-326.
  12. Stern RC, Liu K, Dodd LG. Cytomorphologic features of sebaceous carcinoma on fine needle aspiration. Acta Cytol. 2000;44:760-764. https://doi.org/10.1159/000328558
  13. Jain P, Nanda A, Handa U, Bal A, Mohan H, Gupta SK. FNA diagnosis of recurrent sebaceous carcinoma. Diagn Cytopathol. 2006;34:124-126. https://doi.org/10.1002/dc.20424
  14. Marnouche el A, Maghous A, Kadiri S. Sebaceous carcinoma of the parotid gland: a case report and review of the literature. J Med Case Rep. 2016;10:174. https://doi.org/10.1186/s13256-016-0946-z
  15. Hasebe T, Mukai K, Yamaguchi N. Prognostic value of immunohistochemical staining for proliferating cell nuclear antigen, p53, and c-erbB-2 in sebaceous gland carcinoma and sweat gland carcinoma: comparison with histopathological parameter. Mod Pathol. 1994;7:37-43.
  16. MacFarlane JK, Viloria JB, Palmer JD. Sebaceous cell carcinoma of the parotid gland. Am J Surg. 1975;130:499-501. https://doi.org/10.1016/0002-9610(75)90494-8
  17. Callahan EF, Appert DL, Roenigk RK, Bartley GB. Sebaceous carcinoma of the eyelid: a review of 14 cases. Dermatol Surg. 2004;30:1164-1168. https://doi.org/10.1111/j.1524-4725.2004.30348.x
  18. Jung YH, Woo IS, Kim MY, Han CW, Rha EY. Palliative 5-fluorouracil and cisplatin chemotherapy in recurrent metastatic sebaceous carcinoma: Case report and literature review. Asia Pac J Clin Oncol. 2016;12:e189-193. https://doi.org/10.1111/ajco.12088
  19. Park SK, Park J, Kim HU, Yun SK. Sebaceous Carcinoma: Clinicopathologic Analysis of 29 Cases in a Tertiary Hospital in Korea. J Korean Med Sci. 2017;32:1351-1359. https://doi.org/10.3346/jkms.2017.32.8.1351