Korean Journal of Exercise Nutrition (운동영양학회지)

한국운동영양학회
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Potential role of phytochemicals in brain plasticity: Focus on polyunsaturated fatty acids

  • Yook, Jang Soo (Center for Functional Connectomics, Brain Science Institute, Korea Institute of Science and Technology (KIST)) ;
  • Lee, Minchul (Department of Sports Medicine, CHA University)
  • Received : 2020.02.14
  • Accepted : 2020.03.16
  • Published : 2020.03.31
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Abstract

[Purpose] Functional foods are thought to strongly influence the structure and function of the brain. Previous studies have reported that brain-boosting diets may enhance neuroprotective functions. Certain foods are particularly rich in nutrients like phytochemicals that are known to support brain plasticity; such foods are commonly referred to as brain foods. [Methods] In this review, we briefly explore the scientific evidence supporting the neuroprotective activity of a number of phytochemicals with a focus on phenols and polyunsaturated fatty acids such as flavonoid, olive oil, and omega-3 fatty acid. [Results] The aim of this study was to systematically examine the primary issues related to phytochemicals in the brain. These include (a) the brain-gut-microbiome axis; (b) the effects of phytochemicals on gut microbiome and their potential role in brain plasticity; (c) the role of polyunsaturated fatty acids in brain health; and (d) the effects of nutrition and exercise on brain function. [Conclusion] This review provides evidence supporting the view that phytochemicals from medicinal plants play a vital role in maintaining brain plasticity by influencing the brain-gut-microbiome axis. The consumption of brain foods may have neuroprotective effects, thus protecting against neurodegenerative disorders and promoting brain health.

Keywords

Acknowledgement

This work was supported by the industry academic cooperation foundation fund, CHA University Grant (CHA-201901490001). We would like to thank Editage (www.editage.co.kr) for English language editing. The authors declare no conflicts of interests, financial or otherwise.

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