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Effects of Sunsik Following Steaming and Drying Nine Times on Antioxidative Activity in Obese Rats Fed a High-Fat Diet

구증구포로 제조한 선식이 고지방 식이를 섭취한 비만 쥐의 생체 내 항산화력에 미치는 영향

  • Hwang, Kyung-Hee (Dept. of Faculty of Food, Nutrition and Cookery, Keimyung College University)
  • 황경희 (계명문화대학교 식품영양조리학부)
  • Received : 2020.09.25
  • Accepted : 2020.10.07
  • Published : 2020.10.31

Abstract

The purpose of this study was to investigate the effects of nine times repetitive steaming and drying process Sunsik diets on antioxidant activity in obese mice fed high fat diets to prevent oxidative stress, using drying materials comprising 23 kinds of cereals (61.5%), beans (30.0%), sweet potato and potato (3.0%), fruits (2.0%), vegetables (3.0%), and stevioside, a natural sweetener (0.5%). We produced three samples: the experimental group was classified into the normal diet group (control), the high fat diet group (HF), and the high fat diet group + the Sunsik group (3HFS, 7HFS, 9HFS) fed to the mice for eight weeks. As a result, the serum, liver lipid peroxide, and nitric oxide levels were significantly higher in the HF group than in the C group at p<0.05 level, and the NO level was lower in the Sunsik supplemented groups. The antioxidant enzyme catalase activity significantly decreased in the HF group at the p<0.05 level compared to the C group. The total antioxidant activity of the C group was significantly higher in serum, liver, and kidney tissues than the HF group (p<0.05). The anthocyanin level in liver and spleen tissue was significantly higher in the group fed Sunsik than in the HF group.

Keywords

References

  1. Akcakaya H, Tok S, Dal F, Cinar SA, Nurten R. 2017. ${\beta}$-carotene treatment alters the cellular death process in oxidative stress-induced K562 cells. Cell Biol Int 41:309-319 https://doi.org/10.1002/cbin.10727
  2. Akitha MK, Gondi M, Sakthivelu G, Giridhar P, Rajasekaran T, Ravishankar GA. 2009. Functional attributes of soybean seeds and products with reference to isoflavone content and antioxidant activity. Food Chem 114:771-776 https://doi.org/10.1016/j.foodchem.2008.10.011
  3. Amarowicz R, Estrella I, Hernandes T, Troszynska A. 2008. Antioxidant activity of extract of adzuki bean and its fractions. J Food Lipids 15:119-136 https://doi.org/10.1111/j.1745-4522.2007.00106.x
  4. Ariga T, Hamano M. 1990. Radical scavenging action and its mode in procyanidins B-1 and B-3 from azuki beans to peroxyl radicals. Agric Biol Chem 54:2499-2504 https://doi.org/10.1271/bbb1961.54.2499
  5. Ban SS, Yoon HD, Shin OC, Shin YJ, Park CS, Park JH, Seo BI. 2006. The effects of Artemisiae capillaris, Ponciri frotcus and Cartaegi fructus in obese rats induced by high fat diet. Korean J Herbol 21:55-67
  6. Behr GA, da Silva EG, Ferreira AR, Cerski CT, Dal-Pizzol F, Moreira JC. 2008. Pancreas ${\beta}$-cells morphology, liver antioxidant enzymes and liver oxidative parameters in alloxanresistant and alloxan-susceptible wistar rats: A viable model system for the study of concepts into reactive oxygen species. Fundam Clin Pharmacol 22:657-666 https://doi.org/10.1111/j.1472-8206.2008.00628.x
  7. Bonomini F, Rodella LF, Rezzani R. 2015. Rezzani R. Metabolic syndrome, aging and involvement of oxidative stress. Aging Dis 6:109-120 https://doi.org/10.14336/AD.2014.0305
  8. Choi JH, Hwang SJ, Jeong SN, Lee YK, Jin MH, Park SG, Lee CK. 2009. Anti-aging effect on skin with 9 repetitive steaming and fermenting process herbal composition extract. J Herbol 24:101-106
  9. Chung S, Ha K, Lee HS, Kim C, Joung H, Paik HY, Song Y. 2015. Soft drink consumption is positively associated with metabolic syndrome risk factors only in Korean women: Data from the 2007-2011 Korea National Health and Nutrition Examination Survey. Metabolism 64:1477-1484 https://doi.org/10.1016/j.metabol.2015.07.012
  10. Demirbag R, Yilmaz R, Gur M, Celik H, Guzel S, Selek S, Kocyigit A. 2006. DNA damage in metabolic syndrome and its association with antioxidative and oxidative measurements. Int J Clin Prac 60:1187-1193 https://doi.org/10.1111/j.1742-1241.2006.01042.x
  11. Fight I, Clifton P. 2006. Cereal grains and legumes in the prevention of coronary heart disease and stoke: A review of the literature. Eur J Clin Nutr 60:1145-1159 https://doi.org/10.1038/sj.ejcn.1602435
  12. Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, Gordon DJ, Krauss RM, Savage PJ, Smith SC Jr, Spertus JA, Costa F. 2005. Diagnosis and management of the metabolic syndrome: An American heart association/National heart, lung, and blood institute scientific statement. Circulation 112:2735-2752 https://doi.org/10.1161/CIRCULATIONAHA.105.169404
  13. Ham D, Jun S, Kang M, Shin S, Wie GA, Baik HW, Joung H. 2017. Association of total dietary antioxidant capacity with oxidative stress and metabolic makers among patients with metabolic syndrome. J Nutr Health 50:246-256 https://doi.org/10.4163/jnh.2017.50.3.246
  14. Havel PJ, Uriu-Hare JY, Liu T, Stanhope KL, Stern JS, Keen CL, Ahren B. 1998. Marked and rapid decreases of circulating leptin in streptozotocin diabetic rats: Reversal by insulin. Am J Physiol Regul Integr Comp Physiol 274:R1482-R1491 https://doi.org/10.1152/ajpregu.1998.274.5.R1482
  15. Ho E, Chen G, Bray TM. 1999. Supplementation of N-acetylcysteine inhibits $NF{\kappa}B$ activation and protects againt alloxan in duced diabetes in CD-1 mice. FASEB J 13:1 845-1854 https://doi.org/10.1096/fasebj.13.13.1845
  16. Hwang KH, Kong HJ, Lee EH, Choi EM), Hwang SJ, Jang JH, Yang KM.. 2015. Effects of Sunsik prepared through steaming-drying cycles on blood glucose and inflammatory marker in rats fed high fat. J East Asian Soc Dietary Life 25:111-120 https://doi.org/10.17495/easdl.2015.2.25.1.111
  17. Jo EJ, Kang SJ, Kim AJ. 2009. Effets of steam-and dryprocessing temperatures on the benzo(a)pyrene content of black and red ginseng. Korean J Food Nutr 22:199-204
  18. Joo EY, Park CS. 2010. Antioxidative and fibrinolytic activity of extracts from soybean and Chundkukjang (fermented soybeans) prepared from a black soybean cultivar. Korean J Food Preserv 17:874-880
  19. Jun S, Shin S, Joung H. 2016. Estimation of dietary flavonoid intake and major food sources of Korean adults. Br J Nutr 115:480-489 https://doi.org/10.1017/S0007114515004006
  20. Kim HY, Seo HY, Seo WD, Lee MJ, Choi MS, Ham H. 2020. Effect on angiotensin-I converting enzyme inhibition and antioxidant activities of soybean (Glycine max L.) following steaming and drying nine times. Korean J Food Nutr 33:167-173 https://doi.org/10.9799/KSFAN.2020.33.2.167
  21. Kim JH, Park PS, Kim JK. 2005. Manufacture of nutritionally balanced "Sunsik" for the moderns: Its quality characteristics. Korean J Food Preserv 12:123-129
  22. Kim SA, Jun S, Joung H. 2016. Estimated dietary intake of vitamin A in Korean adults: Based on the Korea National Health and Nutrition Examination Survey 2007-2012. J Nutr Health 49:258-268 https://doi.org/10.4163/jnh.2016.49.4.258
  23. Lee AR, Kwon OJ, Noh JS, Roh SS. 2016. Protective effects of Gastrodia elata extract by steaming time on acute gastritis. Korean J Food Sci Technol 48:597-603 https://doi.org/10.9721/KJFST.2016.48.6.597
  24. Lowenstein CJ, Dinerman JL, Snyder SH. 1994. Nitric oxide: A physiological messenger. Ann Intern Med 120:227-237 https://doi.org/10.7326/0003-4819-120-3-199402010-00009
  25. Mecocci P, MacGarvery U. Kaufman ae, Koontz D, Shoffner JM, Wallace DC, Beal MF. 1993. Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain. Ann Neurol 34:609-616 https://doi.org/10.1002/ana.410340416
  26. Myung JE, Hwang IK. 2008. Functional components and antioxidative activities of soybean extracts. Korean Soybean Digest 25:23-29
  27. Park HS, Jang YJ, Choi DS, Namgung MA, Lee YJ, Kang SA. 1995. Increased oxdative stress in sciatic nerves of streptozotocin induced diabetic rats: Lack of vitamin C effect. Diabetes 19:279-286
  28. Park JH, Kim SY, Lee YJ, Park EJ. 2019. Effect of Sulgidduk added with pine needle juice on the body fat and antioxidant metabolism in high-fat induced obese rats. J Korean Soc Food Sci Nutr 48:170-178 https://doi.org/10.3746/jkfn.2019.48.2.170
  29. Park YE, Cho JH, Cho HM, Yi JY, Seo HW, Choung MG. 2009. A new potato cultivar "Hongyoung", with red skin and flesh color, and high concentrations of anthocyanins. Korean J Breed Sci 41:502-506
  30. Ramirez-Tortosa C, Andersen OM, Gardner PT, Morrice PC, Wood SG, Duthie SJ, Collins AR, Duthie GG. 2001. Anthocyanin-rich extract decreases indices of lipid peroxidation and DNA damage in vitamin E depleted rats. Free Radic Biol Med 31:1033-1037 https://doi.org/10.1016/S0891-5849(01)00618-9
  31. Rho SS, Park JH. 2008. The effets of ginseng radix preparata extract on anti-thrombotic activity. J East West Med 2:47-61
  32. Ryu SH. 2002. Studies on antioxidative effects and antioxidative components of soybean and chongkukjang. Ph.D. Thesis, Inje Univ. Seoul. Korea
  33. Santini SA, Marra G, Giardina B, Cotroneo P, Mordente A, Martorana GE, Manto A, Ghirlanda G. 1997. Defective plasma antioxidant defenses and enhanced susceptability to peroxidant in uncomplicated IDDM. Diabetes 46:1853-1858 https://doi.org/10.2337/diab.46.11.1853
  34. Simao AN, Dichi JB, Barbosa DS, Cecchini R, Dichi I. 2008. Influence of uric acid and gamma-glutamyltransferase on total antioxidant capacity and oxidative stress in patients with metabolic syndrome. Nutrition 24:675-681 https://doi.org/10.1016/j.nut.2008.03.021
  35. Song S, Kim EK, Hong S, Shin S, Song Y, Baik HW, Joung H, Paik HY. 2015. Low consumption of fruits and dairy foods is associated with metabolic syndrome in Korean adults from outpatient clinics in and near Seoul. Nutr Res Pract 9:554-562 https://doi.org/10.4162/nrp.2015.9.5.554
  36. Wiecek A, Kokot F, Chudek J, Adamczak M. 2002. The adipose tissue-a novel endocrine organ of interest to the nephrologist. Nephrol Dial Transplant 17:191-195
  37. Woo JW. 1989. Physico-chemical properties of proteins, lipids and dietary fibers of job's tears (Yulmoo: Coix lachryma-jobi L. var. ma-yuen stapf. & Yeomjoo: Coix lachryma-jobi L.). Ph.D. Thesis, Yonsee Univ. Seoul. Korea
  38. Yan SD, Schmidt AM, Anderson GM, Zhang J, Brett J, Zou YS, Pinsky D, Stern D. 1994. Enhanced cellular oxidant stress by the interaction of advanced glycosylation end products with their receptors/binding protein. J Biol Chem 269:9889-9897 https://doi.org/10.1016/S0021-9258(17)36966-1
  39. Yokozawa T, Satoh A, Cho EJ. 2004. Ginsenoside-Rd attenuates oxidative damage related to aging in senescence-accelerated mice. J Pharm Pharmacol 56:107-113 https://doi.org/10.1211/0022357022449