Applied Chemistry for Engineering (공업화학)

The Korean Society of Industrial and Engineering Chemistry (한국공업화학회)
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Hydrolysis of DFP Using Cu(II)-Lactic Acid and Cu(II)-LMWS-Chitosan Chelates

Cu(II)-Lactic Acid와 Cu(II)-LMWS-Chitosan 착물의 DFP 가수분해반응 연구

  • Kye, Young-Sik (Department of Physics and Chemistry, Korea Military Academy) ;
  • Jeong, Keunhong (Department of Physics and Chemistry, Korea Military Academy) ;
  • Kim, Dongwook (Department of Physics and Chemistry, Korea Military Academy)
  • 계영식 (육군사관학교 물리화학과) ;
  • 정근홍 (육군사관학교 물리화학과) ;
  • 김동욱 (육군사관학교 물리화학과)
  • Received : 2020.07.20
  • Accepted : 2020.07.29
  • Published : 2020.10.12
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Abstract

Chelates synthesized with Cu(II) ion and lactic acid or chitosan were applied to the hydrolysis of organophosphate simulant, DFP (diisopropyl fluorophosphate). Under the homogeneous reaction condition, Cu(II)-lactic acid chelate hydrolyzed DFP with the half life time of 37.1 min. Cu(II)-LMWS chitosan chelate was synthesized with 1 kDa molecular weight of chitosan, which showed low solubility, and then crystallized. The half life time for hydrolyzing DFP using Cu(II)-LMWS chitosan was 32.9 h indicating that the reaction rate is enhanced as much as 16 times more than that of using 18 kDa chitosan-Cu(II) complex. Under the homogeneous reaction condition, the half life time of Cu(II)-LMWS chitosan was 8.75 h. Therefore, we found out that the solubility of Cu(II)-LMWS chitosan makes the difference in the reaction rate as much as 4 times.

Lactic acid와 키토산을 Cu(II) 이온과 반응시켜 합성한 착물을 사용하여 유기인 유사 독성물질인 DFP (Diisopropyl fluorophosphate) 분해반응에 적용하였다. Cu(II)-lactic acid 착물의 경우 homogeneous 상태에서 분해반응 반감기가 37. 1 min으로 분해성능이 우수하였다. 1 kDa 저분자량 수용성 키토산으로 합성한 Cu(II)-LMWS chitosan 착물은 결정화 후에는 용해도가 낮아 heterogeneous 한 상태에서 분해반응이 진행되었으며 그 반감기는 32.9 h이었다. 이 결과는 기존에 연구된 18 kDa 키토산 Cu(II)착물의 분해반응속도보다 약 16배 정도 증가된 것이다. Cu(II)-LMWS chitosan 착물을 결정화하지 않고 homogeneous한 상태로 진행한 분해반응에서는 반감기가 8.75 h로 용해도에 따라 약 4배의 차이를 확인할 수 있었다.

Keywords

References

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