DOI QR코드

DOI QR Code

Underestimation of Dietary Exposure to Pesticide Residues in Relation to Residue Definition in South Korea

국내 잔류농약 residue definition과 관련된 식이노출의 과소평가

  • Lee, Mi-Gyung (Department of Food Science and Biotechnology, Andong National University)
  • 이미경 (안동대학교 식품생명공학과)
  • Received : 2020.08.11
  • Accepted : 2020.08.27
  • Published : 2020.10.30

Abstract

In this study we aimed to find out pesticide types with probability for underestimation of dietary exposure to pesticide residues in Korea by comparing the residue definitions between Korea and Codex standards. In addition, we sought to establish priorities regarding the necessity of review concerning pesticide types and their impacts based on the risk assessment and dietary exposure underestimation. As a result, we found that according to the residue definition information, 44 pesticides have probability for underestimation in terms of dietary exposure assessments. Among them, 24 pesticides have priority for review of dietary exposure underestimation and its impacts on risk assessment, based on the ADI values of pesticides, Korean MRL information and toxicological information of metabolite. The 24 pesticides were as follows: acibensolar-S-methyl, chlorfenapyr, chlorothalonil, cyantraniliprole, cyclaniliprole, cyflumetofen, dithiocarbamates, fenamidone, fenpyroximate, fluazifop-P-butyl, fluopicolide, flupyradifuron, fluxapyroxad, glyphosate, hexythiazox, isoprothiolane, isopyrazam, myclobutanil, penthiopyrad, propiconazole, spinetoram, spiromesifen, spirotetramat, trifloxystrobin. Furthermore, chlorfenapyr, chlorothalonil, dithiocarbamates and fenamidone may have considered a top priority for review due to greater toxicity of metabolite. This study could be of great use for improvement on risk assessment approaches in South Korea regarding pesticide residues in food commodities.

본 연구는 식물성 식품에 대한 잔류농약의 국내와 코덱스의 residue definition 비교를 통해 국내에서 식이노출 과소평가의 가능성이 있는 농약성분을 파악하고 더 나아가 식이노출 과소평가가 위해성 평가에 미치는 영향에 대해 우선적으로 검토가 필요한 농약성분을 알아내고자 하였다. 연구결과, 국내와 코덱스의 residue definition 정보로부터 식이노출 과소평가의 가능성이 있는 44종의 농약성분이 파악되었다. 이들 성분 중 농약성분의 ADI값, 국내 MRL 정보 및 대사물질의 독성학적 정보에 근거하여 다음의 24종 농약성분이 식이노출 과소평가가 위해성 평가에 미치는 영향에 대해 우선적으로 검토가 필요한 것으로 나타났다: acibensolar-S-methyl, chlorfenapyr, chlorothalonil, cyantraniliprole, cyclaniliprole, cyflumetofen, dithiocarbamates, fenamidone, fenpyroximate, fluazifop-P-butyl, fluopicolide, flupyradifuron, fluxapyroxad, glyphosate, hexythiazox, isoprothiolane, isopyrazam, myclobutanil, penthiopyrad, propiconazole, spinetoram, spiromesifen, spirotetramat, trifloxystrobin. 더 나아가 chlorfenapyr, chlorothalonil, dithiocarbamates, fenamidone은 대사물질의 독성이 더 커서 특히 우선적으로 검토가 요구되는 것으로 판단된다. 본 연구는 식품 중 잔류농약에 대한 국내 위해성 평가방법의 개선을 위해 활용될 수 있을 것으로 기대된다.

Keywords

References

  1. Organization for Economic Co-operation and Development, 2006. Guidance Document on the Definition of Residue, Series on Testing and Assessment No. 63. OECD, Paris, pp. 17-23.
  2. Food and Agriculture Organization of the United States (2020, July 1). Proposed residue definition and maximum residue limits. Retrieved from http://www.fao.org/pesticideregistration- toolkit/registration-tools/data-requirements-and-testing-guidelines/study-detail/en/c/1186791
  3. European Food Safety Authority, Guidance on the establishment of the residue definition for dietary risk assessment. EFSA J., 14, 1-129 (2016).
  4. U.S. Environmental Protection Agency, (2020, July 10). Setting tolerances for pesticide residues in foods. Retrieved from https://www.epa.gov/pesticide-tolerances/setting-tolerances-pesticide-residues-foods
  5. Ministry of Food and Drug Safety, 2017. Principles of Standard Setting on Foods and Others. MFDS, Cheongju, Korea, pp. 13-14.
  6. Ministry of Food and Drug Safety, 2019. 2018 The R&D Annual Report of Ministry of Food and Drug Safety (ABSTRACT). MFDS, Cheongju, Korea, pp. 63.
  7. Ministry of Food and Drug Safety, 2020. Notification 2020-24, Appendix 4. MFDS, Cheongju, Korea, pp. 2-113.
  8. Ministry of Food and Drug Safety, 2020. Pesticide MRLs for Agricultural Commodities. MFDS, Cheongju, Korea, pp. 20-230.
  9. FAO/WHO Codex Committee on Pesticide Residues, 2019. CCPR, Agenda Item 6. FAO/WHO, Rome, Italy, pp. 1-379.
  10. Joint FAO/WHO Meeting on Pesticide Residues, 2014. Pesticide Residues in Food. FAO/WHO, Rome, Italy, pp. 117-120.
  11. Joint FAO/WHO Meeting on Pesticide Residues, 2019. Pesticide Residues in Food. FAO/WHO, Rome, Italy, pp. 111-116.