DOI QR코드

DOI QR Code

Extranodal Malignant Lymphoma Concurrent Involving Female Urethra and Cervix: a Case Report

  • Kim, Dong Chan (Department of Radiology, Dankook University Hospital) ;
  • Kim, You Me (Department of Radiology, Dankook University Hospital)
  • Received : 2020.05.20
  • Accepted : 2020.07.02
  • Published : 2020.09.30

Abstract

Extranodal lymphoma presents in almost one-third of all non-Hodgkin lymphoma cases. The gastrointestinal tract, skin, and central nervous system are common sites of involvement, whereas the urethra and cervix are very rare. To the best of our knowledge, this is the first report on concurrent extranodal involvement of the uterine cervix and urethra. We report imaging findings of malignant lymphoma involving urethra and cervix concurrently in a 79-year-old female patient with literature review. The magnetic resonance imaging showed huge intermediate to high signal intensity mass on T2 weighted images and strong homogeneous enhancement in uterine cervix and periurethral area, but no surrounding architectural disruption.

Keywords

References

  1. Lopez-Guillermo A, Colomo L, Jimenez M, et al. Diffuse large B-cell lymphoma: clinical and biological characterization and outcome according to the nodal or extranodal primary origin. J Clin Oncol 2005;23:2797-2804 https://doi.org/10.1200/JCO.2005.07.155
  2. Krol AD, le Cessie S, Snijder S, Kluin-Nelemans JC, Kluin PM, Noordijk EM. Primary extranodal non-Hodgkin's lymphoma (NHL): the impact of alternative definitions tested in the Comprehensive Cancer Centre West population-based NHL registry. Ann Oncol 2003;14:131-139 https://doi.org/10.1093/annonc/mdg004
  3. Zucca E, Roggero E, Bertoni F, Cavalli F. Primary extranodal non-Hodgkin's lymphomas. Part 1: Gastrointestinal, cutaneous and genitourinary lymphomas. Ann Oncol 1997;8:727-737 https://doi.org/10.1023/A:1008282818705
  4. Zucca E, Roggero E, Bertoni F, Conconi A, Cavalli F. Primary extranodal non-Hodgkin's lymphomas. Part 2: Head and neck, central nervous system and other less common sites. Ann Oncol 1999;10:1023-1033 https://doi.org/10.1023/A:1008313229892
  5. Moller MB, Pedersen NT, Christensen BE. Diffuse large B-cell lymphoma: clinical implications of extranodal versus nodal presentation--a population-based study of 1575 cases. Br J Haematol 2004;124:151-159 https://doi.org/10.1046/j.1365-2141.2003.04749.x
  6. Chiu BC, Weisenburger DD. An update of the epidemiology of non-Hodgkin's lymphoma. Clin Lymphoma 2003;4:161-168 https://doi.org/10.3816/CLM.2003.n.025
  7. Masuda A, Tsujii T, Kojima M, et al. Primary mucosaassociated lymphoid tissue (MALT) lymphoma arising from the male urethra. A case report and review of the literature. Pathol Res Pract 2002;198:571-575 https://doi.org/10.1078/0344-0338-00304
  8. Muntz HG, Ferry JA, Flynn D, Fuller AF Jr, Tarraza HM. Stage IE primary malignant lymphomas of the uterine cervix. Cancer 1991;68:2023-2032 https://doi.org/10.1002/1097-0142(19911101)68:9<2023::AID-CNCR2820680930>3.0.CO;2-V
  9. Onyiuke I, Kirby AB, McCarthy S. Primary gynecologic lymphoma: imaging findings. AJR Am J Roentgenol 2013;201:W648-655 https://doi.org/10.2214/AJR.12.8907
  10. Shimizu Y, Ogawa O, Terachi T, Okada Y, Yoshida O. A case of primary urethral lymphoma presenting as a huge mass surrounding the female urethra. Hinyokika Kiyo 1997;43:229-232