Journal of Environmental Health Sciences (한국환경보건학회지)

Korean Society of Environmental Health (한국환경보건학회)
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Environmental Exposure to Tobacco-specific Nitrosamines in an Area Near a Fertilizer Plant

비료제조공장 인근 지역의 담배특이니트로사민 환경 노출

  • Ha, Jae-Na (Environmental Research Department, National Institute of Environmental Research) ;
  • Yoon, Mi-Ra (Environmental Research Department, National Institute of Environmental Research) ;
  • Chang, Jun Young (Environmental Research Department, National Institute of Environmental Research) ;
  • Koh, Dohyun (Institute for Environmental Safety and Health) ;
  • Shin, Ho-Sang (Department of Environmental Education, Kongju National University) ;
  • Kim, Suhyang (Sunil Engineering and Consultant, Corporation) ;
  • Lee, Chul-Woo (Environmental Research Department, National Institute of Environmental Research) ;
  • Lee, Bo-Eun (Environmental Research Department, National Institute of Environmental Research) ;
  • Kim, Jeong-Soo (Institute for Environmental Safety and Health)
  • 하재나 (국립환경과학원 환경건강연구부 환경보건연구과) ;
  • 윤미라 (국립환경과학원 환경건강연구부 환경보건연구과) ;
  • 장준영 (국립환경과학원 환경건강연구부 환경보건연구과) ;
  • 고도현 (협동조합 환경안전건강연구소) ;
  • 신호상 (공주대학교 환경교육과) ;
  • 김수향 (주식회사 선일이앤씨) ;
  • 이철우 (국립환경과학원 환경건강연구부 환경보건연구과) ;
  • 이보은 (국립환경과학원 환경건강연구부 환경보건연구과) ;
  • 김정수 (협동조합 환경안전건강연구소)
  • Received : 2020.07.08
  • Accepted : 2020.08.12
  • Published : 2020.08.31
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Abstract

Objectives: This study aimed to evaluate environmental exposure to tobacco-specific nitrosamines (TSNAs) by conducting an analysis of the concentration of TSNAs in deposited dust collected from a fertilizer plant and the surrounding village, a simulation of high-temperature drying of tobacco waste, and CALPUFF modeling. Methods: The raw materials of the products, deposited dust (inside and outside the plant and residential area), soil, and wastewater were sampled and the TSNA concentrations were analyzed by LC-MS/MS. As the plant was closed down before the investigation, simulation tests were conducted to confirm the substances discharged during high-temperature (300℃) drying of tobacco waste. CALPUFF modeling was performed to identify the area of influence due to exposure to TSNAs. Results: TSNAs were detected in organic fertilizers estimated to contain tobacco waste, deposited dust, and soil collected from inside and outside the plant. N'-nitrosonornicotine (NNN), 4-(methylnitrosoamino)-1-(3-pyridyl)-1-butanone (NNK), and N'-nitrosoanatabine (NAT) components were detected in five of 15 deposited dust samples collected from the residential area around the plant, while TSNAs were not detected in the five sampling points in the control area. Also, the simulation test for the high temperature drying of tobacco waste found emissions of TSNAs. The CALPUFF modeling results showed that the survey area was likely to be included in the area of influence of TSNA emissions from the plant. Conclusions: It is estimated that harmful tobacco ingredients such as TSNAs were dispersed in nearby areas due to the illegal use of tobacco waste as a raw material to produce organic fertilizers at the plant. These findings assume that the residents have been exposed to TSNAs and suggest that the need for the establishment of measures to manage environmental health.

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