The Korean Journal of Food And Nutrition (한국식품영양학회지)

The Korean Society of Food and Nutrition (한국식품영양학회)
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Improvement in Exercise Endurance by Hovenia dulcis Fruit Hot Water Extract in Mice

헛개나무열매 열수추출물 투여에 의한 흰쥐의 지구력 향상 효과

  • Kwon, Tae-Hyung (Dept. of Research and Development, Chuncheon Bio-Industry Foundation) ;
  • Han, Joon-Hee (Dept. of Research and Development, Chuncheon Bio-Industry Foundation) ;
  • Lee, Sun-Yeop (Dept. of Research and Development, Chuncheon Bio-Industry Foundation) ;
  • Yu, Keun-Hyung (Dept. of Research and Development, Chuncheon Bio-Industry Foundation)
  • 권태형 ((재)춘천바이오산업진흥원 기술개발실) ;
  • 한준희 ((재)춘천바이오산업진흥원 기술개발실) ;
  • 이선엽 ((재)춘천바이오산업진흥원 기술개발실) ;
  • 유근형 ((재)춘천바이오산업진흥원 기술개발실)
  • Received : 2020.03.29
  • Accepted : 2020.07.18
  • Published : 2020.08.31
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Abstract

This study was designed to evaluate the improvement in exercise endurance by Hovenia dulcis fruit hot water extract (HDWE) for the potential application as a functional food material. The effect was based on the evaluation of the forced-swimming capacity and changes in biochemical parameters in mice. Six-week-old mice were classified into four groups based on a randomized block design: the negative control group, the HDWE 50 mg/kg body weight group, the HDWE 200 mg/kg body weight group, and the 1-octacosanol 50 mg/kg body weight group (n=8 mice per group). The swimming exercise time in the HDWE-50 group was increased at 545±43 sec compared to the control group at 263±28 sec. The HDWE-200 fatigue indicators, lactate acid and ammonia content, decreased to 4.99±0.33 mg/mL and 0.63±0.05 mg/mL, respectively. In addition, the content of glycogen in the liver and muscle tended to increase in the group administered HDWE but was not significant. Likewise, the LDH and glucose contents were increased compared to the control group. The muscle damage indicators ALT (52.7±2.6 U/L) and AST (42.5±5.2 U/L) tended to decrease compared to the control group (76.4±10.2 U/L).

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References

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