Archives of Plastic Surgery

Korean Society of Plastic and Reconstructive Surgeons (대한성형외과학회)
권호 표지
DOI QR코드

DOI QR Code

Basic rheology of dermal filler

  • Received : 2020.04.24
  • Accepted : 2020.06.22
  • Published : 2020.07.15
Download PDF
⟨ Previous Next ⟩

Abstract

Dermal injectables are the most popular material for facial enhancement, including volumizing and wrinkle correction. However, although hyaluronic acid is the most common component of dermal injectables, the character of hyaluronic acid products is quite variable. These materials can be described in terms of their viscoelastic properties using four parameters. In this article, the author would like to describe these properties in detail. Although many physicians consider this material to be convoluted, thoroughly understanding the characteristics of various injectables enables us to tailor procedures accordingly and to enhance the final results.

Keywords

References

  1. Kontis TC. Contemporary review of injectable facial fillers. JAMA Facial Plast Surg 2013;15:58-64. https://doi.org/10.1001/jamafacial.2013.337
  2. Cavallini M, Gazzola R, Metalla M, et al. The role of hyaluronidase in the treatment of complications from hyaluronic acid dermal fillers. Aesthet Surg J 2013;33:1167-74. https://doi.org/10.1177/1090820X13511970
  3. Flynn TC, Sarazin D, Bezzola A, et al. Comparative histology of intradermal implantation of mono and biphasic hyaluronic acid fillers. Dermatol Surg 2011;37:637-43. https://doi.org/10.1111/j.1524-4725.2010.01852.x
  4. Nast A, Reytan N, Hartmann V, et al. Efficacy and durability of two hyaluronic acid-based fillers in the correction of nasolabial folds: results of a prospective, randomized, double-blind, actively controlled clinical pilot study. Dermatol Surg 2011;37:768-75. https://doi.org/10.1111/j.1524-4725.2011.01993.x
  5. Kablik J, Monheit GD, Yu L, et al. Comparative physical properties of hyaluronic acid dermal fillers. Dermatol Surg 2009;35 Suppl1:302-12. https://doi.org/10.1111/j.1524-4725.2008.01046.x
  6. Michaud T. Rheology of hyaluronic acid and dynamic facial rejuvenation: topographical specificities. J Cosmet Dermatol 2018;17:736-43. https://doi.org/10.1111/jocd.12774
  7. Pierre S, Liew S, Bernardin A. Basics of dermal filler rheology. Dermatol Surg 2015;41 Suppl 1:S120-6. https://doi.org/10.1097/DSS.0000000000000334
  8. Tezel A, Fredrickson GH. The science of hyaluronic acid dermal fillers. J Cosmet Laser Ther 2008;10:35-42. https://doi.org/10.1080/14764170701774901
  9. Sundaram H, Rohrich RJ, Liew S, et al. Cohesivity of hyaluronic acid fillers: development and clinical implications of a novel assay, pilot validation with a five-point grading scale, and evaluation of six U.S. Food and Drug Administration-approved fillers. Plast Reconstr Surg 2015;136:678-86. https://doi.org/10.1097/PRS.0000000000001638
  10. Stocks D, Sundaram H, Michaels J, et al. Rheological evaluation of the physical properties of hyaluronic acid dermal fillers. J Drugs Dermatol 2011;10:974-80.
  11. Borrell M, Leslie DB, Tezel A. Lift capabilities of hyaluronic acid fillers. J Cosmet Laser Ther 2011;13:21-7. https://doi.org/10.3109/14764172.2011.552609