한방재활의학과학회지 (Journal of Korean Medicine Rehabilitation)

  • 제30권3호
  • /
  • Pages.103-116
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  • 2020
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  • 1229-1854(pISSN)
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  • 2288-4114(eISSN)
한방재활의학과학회 (The society of Korean Medicine Rehabilitation)
권호 표지
DOI QR코드

DOI QR Code

한약의 류마티스 관절염 동물 모델에 대한 치료효과: 국내 및 국외 논문에 대한 체계적 문헌 고찰

The Effect of Herbal Medicine on Rheumatoid Arthritis Animal Model: A systematic Review of Animal Experiment Studies Published in Korea and Overseas

  • 오승준 (대전대학교 한의과대학 한방재활의학과교실) ;
  • 하현주 (대전대학교 한의과대학 한방재활의학과교실) ;
  • 구지향 (대전대학교 한의과대학 한방재활의학과교실) ;
  • 박양춘 (대전대학교 한의과대학 내과학교실) ;
  • 오민석 (대전대학교 한의과대학 한방재활의학과교실) ;
  • 정인철 (대전대학교 한의과대학 한방신경정신과학교실) ;
  • 이은정 (대전대학교 한의과대학 한방재활의학과교실)
  • Oh, Seung-Joon (Department of Korean Medicine Rehabilitation, College of Korean Medicine, Daejeon University) ;
  • Ha, Hyun Ju (Department of Korean Medicine Rehabilitation, College of Korean Medicine, Daejeon University) ;
  • Gu, Ji-Hyang (Department of Korean Medicine Rehabilitation, College of Korean Medicine, Daejeon University) ;
  • Park, Yang-Chun (Department of Internal Medicine, College of Korean Medicine, Daejeon University) ;
  • Oh, Min-Seok (Department of Korean Medicine Rehabilitation, College of Korean Medicine, Daejeon University) ;
  • Jung, In-Chul (Department of Oriental Neuropsychiatry, College of Korean Medicine, Daejeon University) ;
  • Lee, Eun-Jung (Department of Korean Medicine Rehabilitation, College of Korean Medicine, Daejeon University)
  • 투고 : 2020.06.17
  • 심사 : 2020.07.01
  • 발행 : 2020.07.31
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초록

Objectives This study was designed to review the effect of herbal medicine on animal model with rheumatoid arthritis. Methods We reviewed studies published both in Korea and overseas, all published after 2008. We investigated 8 databases, 6 Korean databases and 2 of abroad. Searching was conducted through flowchart and 24 studies met our guideline. Datas were extrated and organized as animal model characteristics, experimental period, study design, herbal medicine used as intervention and rheumatoid arthritis indicator. Results 336 articles were primarily selected. After screening, 24 articles were left in the end. All 24 studies showed that the herbal medicine used in the animal experiment was effective on treating rheumatoid arthris, proven by macroscopic, histological, hematological and osteological indicators. Conclusions The result showed that herbal medicine is effective in treating rheumatoid arthritis through various pathways. However, study design and intervention were all different from each other and we could not specify the certain compound, material or substance of efficacy. Further study should be conducted to figure out the effectiveness of herbal medicine on rheumatoid arthritis.

키워드

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