Radiation Oncology Journal

  • 제38권2호
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  • Pages.148-150
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  • 2020
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  • 2234-1900(pISSN)
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  • 2234-3156(eISSN)
대한방사선종양학회 (The Korean Society for Radiation Oncology)
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Exceptional response to radiotherapy in unresectable pleuropulmonary blastoma of a child

  • Kim, Jae Sik (Department of Radiation Oncology, Seoul National University Hospital) ;
  • Lee, Joo Ho (Department of Radiation Oncology, Seoul National University Hospital)
  • 투고 : 2020.05.19
  • 심사 : 2020.06.12
  • 발행 : 2020.06.30
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초록

Pleuropulmonary blastoma (PPB) is a rare intrathoracic neoplasm in children. Although surgery with or without chemotherapy mainly conducted, the response of radiotherapy (RT) has not been evaluated yet. For unresectable tumor, RT might be considered as one option to decrease tumor extent to relieve obstructing symptoms or to facilitate successive treatment. We report one child in whom PPB with DICER1 mutation recurred after surgery and lead to respiratory distress. She emergently received palliative RT with a relatively low dose (20 Gy), and symptoms sufficiently relieved. Even she showed an 84.3% reduction in diameter and maintained the remission status for 1 year. These might reflect possible radiosensitivity of PPB, and further investigations of RT might be necessary for unresectable PPB.

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참고문헌

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