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Development and Validation of Questionnaire for Chronic Fatigue Syndrome (CFS) Diagnosis Based on Systemic Exertion Intolerance Disease (SEID) Criteria

전신성 활동불능증(Systemic Exertion Intolerance Disease) 진단 기준을 바탕으로 한 만성 피로 증후군(Chronic Fatigue Syndrome) 진단 설문지 개발 및 신뢰도 평가

  • Lim, Eun-jin (Institute of Bioscience and Integrative Medicine, Dept. of Oriental Medicine College, University of Daejeon) ;
  • Son, Chang-gue (Institute of Bioscience and Integrative Medicine, Dept. of Oriental Medicine College, University of Daejeon) ;
  • Jang, Eun-su (Institute of Bioscience and Integrative Medicine, Dept. of Oriental Medicine College, University of Daejeon)
  • 임은진 (대전대학교 한의학과, 동서생명과학연구원) ;
  • 손창규 (대전대학교 한의학과, 동서생명과학연구원) ;
  • 장은수 (대전대학교 한의학과, 동서생명과학연구원)
  • Received : 2020.03.12
  • Accepted : 2020.06.29
  • Published : 2020.06.30

Abstract

Purpose: This study aimed to develop a questionnaire for the diagnosis of chronic fatigue syndrome (CFS) designed based on the systematic exertion intolerance disorder (SEID) criteria, and to validate the reliability of the questionnaire. Methods: A literature search on questionnaires for CFS diagnosis was conducted to develop a SEID questionnaire (SEID-Q27), followed by a pilot survey to identify the reliability of the questionnaire. Adults (Daejeon university personnel) with a Chalder fatigue scale (CFQ) score ≥15 were invited for the survey. We commenced the survey in November 2019 with a two weeks of interval for the test and retest method. The reliability of the questionnaire was investigated in three angles: 1. Cronbach's α, 2. correlations (r) of the questions, numerical rating scale (NRS), and visual analog scale (VAS), and 3. kappa (k) analysis. Results: Among the total 275 adults registered, 55 (20%) participants with a CFQ score ≥15 were invited, and 31 (11%) [15 male, 16 female] completed the questionnaire. The total Cronbach's α was 0.944 for the test and 0.949 for the retest. The reliability (r) of questions by CFQ score (≥15, ≥18, ≥20) ranged from 0.533-0.928 (p <0.05), and the r score of the NRS and VAS were the highest in CFQ scores ≥20, at 0.933 (p<0.001). The agreement rate of the SEID-Q27 between the test and retest was 87% (kappa k=0.743). Conclusions: The SEID-Q27 seems to be reliable. Further studies are needed to measure the validity of the tool and the cutoff point.

Keywords

References

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Cited by

  1. SEID(Systemic Exertion Intolerance Disease) 진단 기준을 바탕으로 한 만성 피로 증후군 진단 설문지(SEID-Q27) 타당도 연구 vol.41, pp.6, 2020, https://doi.org/10.22246/jikm.2020.41.6.1015