Maxillofacial Plastic and Reconstructive Surgery

  • Volume 42
  • /
  • Pages.5.1-5.9
  • /
  • 2020
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  • 2288-8101(pISSN)
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  • 2288-8586(eISSN)
Korean Association of Maxillofacial Plastic and Reconstructive Surgeons (대한악안면성형재건외과학회)
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Immunomodulation for maxillofacial reconstructive surgery

  • Kim, Seong-Gon (Department of Oral and Maxillofacial Surgery, College of Dentistry, Gangneung-Wonju National University)
  • Received : 2020.01.23
  • Accepted : 2020.02.24
  • Published : 2020.12.31
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Abstract

Immunomodulation is a technique for the modulation of immune responses against graft material to improve surgical success rates. The main target cell for the immunomodulation is a macrophage because it is the reaction site of the graft and controls the healing process. Macrophages can be classified into M1 and M2 types. Most immunomodulation techniques focus on the rapid differentiation of M2-type macrophage. An M2 inducer, 4-hexylresorcinol, has been recently identified and is used for bone grafts and dental implant coatings.

Keywords

Acknowledgement

This study was carried out with the support of "Cooperative Research Program for Agriculture Science and Technology Development (Project no. PJ01313902)" Rural Development Administration, Republic of Korea.

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