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Bee Venom Acupuncture for Shoulder Pain: A Systematic Review and Meta-analysis of Randomized Controlled Trials

  • Shen, Lei (Department of Constitutional Medicine, College of Korean Medicine, Wonkwang University) ;
  • Lee, Jong Ha (Department of Korean Medicine Graduate School of Wonkwang University) ;
  • Joo, Jong Cheon (Department of Constitutional Medicine, College of Korean Medicine, Wonkwang University) ;
  • Park, Soo Jung (Department of Sasang Constitutional Medicine, College of Korean Medicine, Woosuk University) ;
  • Song, Yung Sun (Department of Rehabilitation Medicine, College of Korean Medicine, Wonkwang University)
  • 투고 : 2020.01.23
  • 심사 : 2020.05.18
  • 발행 : 2020.06.30

초록

Objectives: Our review aimed to summarize and evaluate evidence on the effectiveness of bee venom acupuncture (BVA) in the treatment of shoulder pain. Methods: Randomized controlled trials (RCTs) evaluating the effectiveness of BVA on shoulder pain were searched up to October 2019 in 11 electronic databases (Medline, Embase, CENTRAL, CiNii, CNKI, VIP, Wanfang, Kmbase, NDSL, RISS, OASIS). The methodological quality of the included RCTs were evaluated using Cochrane Risk of Bias tool and a meta-analysis was performed. Results: Seven studies were included in the review, and four studies were included in the meta-analysis. Comparing BVA plus conventional therapy (CT) with saline injection plus CT, it showed an effect in favor of BVA plus CT in visual analog scale (VAS) and pain rating scale (PRS) (p = 0.02, p = 0.009, respectively). Comparing BVA plus physiotherapy (PT) with saline injection plus PT, it showed that there was no significant difference in VAS and verbal rating scale (VRS) between the two groups. Conclusion: This systematic review and meta-analysis suggest that BVA could be beneficial as an adjuvant treatment for shoulder pain.

키워드

참고문헌

  1. Kim YS, Jun H, Chae Y, Park HJ, Kim BH, Chang IM, et al. The practice of Korean medicine: an overview of clinical trials in acupuncture. Evid Based Complement Alternat Med. 2005;2(3):325-52. https://doi.org/10.1093/ecam/neh102
  2. Lee WR, Pak SC, Park KK. The protective effect of bee venom on fibrosis causing inflammatory diseases. Toxins (Basel). 2015;7(11):4758-72. https://doi.org/10.3390/toxins7114758
  3. Chen J. Spinal processing of bee venom-induced pain and hyperalgesia. Sheng li xue bao. 2008;60(5):645-652.
  4. Koburova KL, Michailova SG, Shkenderov SV. Further investigation on the antiinflammatory properties of adolapin--bee venom polypeptide. Acta Physiol Pharmacol Bulg. 1985;11(2):50-5.
  5. Park HJ, Son DJ, Lee CW, Choi MS, Lee US, Song HS, et al. Melittin inhibits inflammatory target gene expression and mediator generation via interaction with IkappaB kinase. Biochem Pharmacol. 2007;73(2):237-47. https://doi.org/10.1016/j.bcp.2006.09.023
  6. Urwin M, Symmons D, Allison T, Brammah T, Busby H, Roxby M, et al. Estimating the burden of musculo-skeletal disorders in the community: the comparative prevalence of symptoms at different anatomical sites, and the relation to social deprivation. Ann Rheum Dis. 1998;57(11):649-55. https://doi.org/10.1136/ard.57.11.649
  7. van der Windt DA, Koes BW, Boeke AJ, Deville W, De Jong BA, Bouter LM. Shoulder disorders in general practice: prognostic indicators of outcome. Br J Gen Pract. 1996;46(410):519-23.
  8. Lim SM, Lee SH. Effectiveness of bee venom acupuncture in alleviating post-stroke shoulder pain: a systematic review and meta-analysis. J Integr Med. 2015;13(4):241-7. https://doi.org/10.1016/S2095-4964(15)60178-9
  9. Lee MS, Pittler MH, Shin BC, Kong JC, Ernst E. Bee venom acupuncture for musculoskeletal pain: a review. J Pain. 2008;9(4):289-97. https://doi.org/10.1016/j.jpain.2007.11.012
  10. Chul K, Changhyo K, Il CS. Clinical Value of a New Self Assessment Method of Pain. J Korean Acad Rehabil Med. 1998;22(2):304-11.
  11. Williamson A, Hoggart B. Pain: a review of three commonly used pain rating scales. J Clin Nurs. 2005;14(7):798-804. https://doi.org/10.1111/j.1365-2702.2005.01121.x
  12. Roach KE, Budiman-Mak E, Songsiridej N, Lertratanakul Y. Development of a shoulder pain and disability index. Arthritis Care Res. 1991;4(4):143-9. https://doi.org/10.1002/art.1790040403
  13. Higgins JPT, Green S, eds. Cochrane Handbook for Systematic Reviews of Interventions version 5.1.0 [updated March 2011]. London, England; The Cochrane Collaboration; 2011. Available from: www. chochrane-handbook.org.
  14. Cho SW, Go KH, Nam JH, Kim MS, Lee SY, Lee IS. The Effectiveness of Zingiberis Rhizoma Herbal Acupuncture Therapy and Bee Venom Herbal Acupuncture Therapy on the Poststroke Hemiplegic Shoulder Pain. J Orient Rehabi Med. 2005;15(4):77-87.
  15. Eom JY, Won SH, Kwon KR, Lee HS. Comparative study of Acupuncture, Bee Venom Acupuncture and Bee Venom Herbal Acupuncture on the treatment of Poststroke Hemiplegic Shoulder Pain. J korean Pharmacopuncture institute. 2006;9(1):139-54.
  16. Ko CN, Min IK, Park SW, Jung WS, Moon SK, Park JM. Effectiveness of Bee Venom Acupuncture on Shoulder Pain after Stroke. J Korean Oriental Med. 2007;28(1):11-24.
  17. Lee DY, Yeom SC, Kim DH, Kim DJ, Lee GM. A Clinical Study of Bee Venom Acupuncture Therapy on Shoulder Pain Patients in Stroke Sequelae. J Korean Acupunct Moxib Soc. 2006;23(4):69-80.
  18. Park JA, Lee CH, Kwon KS, Lee KA, Jang KJ. The Effects of Sweet Bee Venom Pharmacopuncture on the Poststroke Hemiplegic Shoulder Pain. J Korean Acupunct Moxib Soc. 2011;28(4):37-47.
  19. Koh PS, Seo BK, Cho NS, Park HS, Park DS, Baek YH. Clinical effectiveness of bee venom acupuncture and physiotherapy in the treatment of adhesive capsulitis: a randomized controlled trial. J Shoulder Elbow Surg. 2013;22(8):1053-62. https://doi.org/10.1016/j.jse.2012.10.045
  20. Park YC, Koh PS, Seo BK, Lee JW, Cho NS, Park HS, et al. Long-term effectiveness of bee venom acupuncture and physiotherapy in the treatment of adhesive capsulitis: A one-year follow-up analysis of a previous randomized controlled trial. J Altern Complement Med. 2014;20(12):919-24. https://doi.org/10.1089/acm.2014.0220
  21. Son DJ, Lee JW, Lee YH, Song HS, Lee CK, Hong JT. Therapeutic application of anti-arthritis, pain-releasing, and anti-cancer effects of bee venom and its constituent compounds. Pharmacol Ther. 2007;115(2):246-70. https://doi.org/10.1016/j.pharmthera.2007.04.004
  22. Lee MJ, Jang M, Choi J, Lee G, Min HJ, Chung WS, et al. Bee Venom Acupuncture Alleviates Experimental Autoimmune Encephalomyelitis by Upregulating Regulatory T Cells and Suppressing Th1 and Th17 Responses. Mol Neurobiol. 2016;53(3):1419-45. https://doi.org/10.1007/s12035-014-9012-2
  23. Jung GB, Huh JE, Lee HJ, Kim D, Lee GJ, Park HK, et al. Anti-cancer effect of bee venom on human MDAMB-231 breast cancer cells using Raman spectroscopy. Biomed Opt Express. 2018;9(11):5703-18. https://doi.org/10.1364/boe.9.005703
  24. Seo BK, Han K, Kwon O, Jo DJ, Lee JH. Efficacy of Bee Venom Acupuncture for Chronic Low Back Pain: A Randomized, Double-Blinded, Sham-Controlled Trial. Toxins (Basel). 2017;9(11).
  25. Lee JA, Son MJ, Choi J, Jun JH, Kim JI, Lee MS. Bee venom acupuncture for rheumatoid arthritis: a systematic review of randomised clinical trials. BMJ Open. 2014;4(11):e006140. https://doi.org/10.1136/bmjopen-2014-006140
  26. Lee JD, Park HJ, Chae Y, Lim S. An Overview of Bee Venom Acupuncture in the Treatment of Arthritis. Evid Based Complement Alternat Med. 2005;2(1):79-84. https://doi.org/10.1093/ecam/neh070
  27. Choi J, Jeon C, Lee JH, Jang JU, Quan FS, Lee K, et al. Suppressive Effects of Bee Venom Acupuncture on Paclitaxel-Induced Neuropathic Pain in Rats: Mediation by Spinal alpha(2)-Adrenergic Receptor. Toxins (Basel). 2017;9(11).
  28. Neviaser AS, Neviaser RJ. Adhesive capsulitis of the shoulder. J Am Acad Orthop Surg. 2011;19(9):536-42. https://doi.org/10.5435/00124635-201109000-00004
  29. Wang W, Shi M, Zhou C, Shi Z, Cai X, Lin T, et al. Effectiveness of corticosteroid injections in adhesive capsulitis of shoulder: A meta-analysis. Medicine (Baltimore). 2017;96(28):e7529. https://doi.org/10.1097/MD.0000000000007529
  30. McLean DE. Medical complications experienced by a cohort of stroke survivors during inpatient, tertiary-level stroke rehabilitation. Arch Phys Med Rehabil. 2004;85(3):466-9. https://doi.org/10.1016/S0003-9993(03)00484-2
  31. Park JS, Park YG, Jang CH, Cho YN, Park JH. Severe Ulnar Nerve Injury After Bee Venom Acupuncture at a Traditional Korean Medicine Clinic: A Case Report. Ann Rehabil Med. 2017;41(3):483-7. https://doi.org/10.5535/arm.2017.41.3.483
  32. Abdulsalam MA, Ebrahim BE, Abdulsalam AJ. Immune thrombocytopenia after bee venom therapy: a case report. BMC Complement Altern Med. 2016;16:107. https://doi.org/10.1186/s12906-016-1091-3