한국해양바이오학회지 (Journal of Marine Bioscience and Biotechnology)

한국해양바이오학회 (The Korean Society for Marine Biotechnology)
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해조류 유래 호흡기 질환 천식 치료제 연구 동향

A Review of Marine Algae-derived Therapeutic Agents for Respiratory Disease Asthma

  • 김태희 (부경대학교 의공학과 및 BK21 Plus 해양 융복합 생명의학기술센터) ;
  • 허성영 (부경대학교 의공학과 및 BK21 Plus 해양 융복합 생명의학기술센터) ;
  • 오건우 (부경대학교 의공학과 및 BK21 Plus 해양 융복합 생명의학기술센터) ;
  • 김민성 (부경대학교 의공학과 및 BK21 Plus 해양 융복합 생명의학기술센터) ;
  • 최일환 (인제대학교 의과대학, 미생물학교실) ;
  • 정원교 (부경대학교 의공학과 및 BK21 Plus 해양 융복합 생명의학기술센터)
  • Kim, Tae-Hee (Department of Biomedical Engineering and Center for Marine-Integrated Biomedical Technology (BK21 Plus), Pukyong National University) ;
  • Heo, Seong-Yeong (Department of Biomedical Engineering and Center for Marine-Integrated Biomedical Technology (BK21 Plus), Pukyong National University) ;
  • Oh, Gun-Woo (Department of Biomedical Engineering and Center for Marine-Integrated Biomedical Technology (BK21 Plus), Pukyong National University) ;
  • Kim, Min-Sung (Department of Biomedical Engineering and Center for Marine-Integrated Biomedical Technology (BK21 Plus), Pukyong National University) ;
  • Choi, Il-Whan (Department of Microbiology, College of Medicine, Inje University) ;
  • Jung, Won-Kyo (Department of Biomedical Engineering and Center for Marine-Integrated Biomedical Technology (BK21 Plus), Pukyong National University)
  • 투고 : 2020.05.14
  • 심사 : 2020.05.25
  • 발행 : 2020.06.30
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초록

Asthma is a complex inflammatory disease of the lung characterized by variable airflow obstruction, airway hyperresponsiveness, airway inflammation, and reduction of respiratory function. Its prevalence and incidence are increasing because of the effect of various environmental and lifestyle risk factors. Steroid inhalation, long-acting agonists, and other synthetic drugs are used for the treatment of this disease. However, they have some side effects and show unsatisfied result and response after treatment. Therefore, many researchers have focused on the development of natural product-related treatment for asthma to suppress the side effects and unsatisfied results. Seaweeds contain various bioactive compounds with anti-inflammatory, antibacterial, and anti-oxidant activities. Thus, we investigated the asthma treatment-related literature using marine algae via the Google scholar search engine. Consequently, the literature is rarely investigated, but is increasing steadily. The literature was performed as a comparison study with an ovalbumin-induced group or drug-treated group, and investigated the antiasthma activity of algae ethanol extract. Although many researchers have studied marine algae-derived therapeutic agents for asthma, the amount of literature is rare compared with those of herbal medicine-derived therapeutic agents. Conclusively, we suggest that many researchers should investigate and develop algae-derived therapeutic agents for asthma treatment.

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참고문헌

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