Journal of the Korean Society of Radiology (대한영상의학회지)

The Korean Society of Radiology (대한영상의학회)
권호 표지
DOI QR코드

DOI QR Code

Immunoglobulin G4-Related Disease of the Ovary Mimicking Bilateral Ovarian Malignancies

양측 난소의 악성 종양으로 오인한 난소의 면역글로불린 G4 관련 질환

  • Yongsik Sim (Department of Radiology, Yonsei University College of Medicine) ;
  • Taek Chung (Department of Pathology, Yonsei University College of Medicine) ;
  • Dae Chul Jung (Department of Radiology, Yonsei University College of Medicine) ;
  • Hyun-Soo Kim (Department of Pathology, Yonsei University College of Medicine) ;
  • Young Taik Oh (Department of Radiology, Yonsei University College of Medicine)
  • 심용식 (연세대학교 의과대학 영상의학교실) ;
  • 정택 (연세대학교 의과대학 병리학교실) ;
  • 정대철 (연세대학교 의과대학 영상의학교실) ;
  • 김현수 (연세대학교 의과대학 병리학교실) ;
  • 오영택 (연세대학교 의과대학 영상의학교실)
  • Received : 2018.11.13
  • Accepted : 2019.10.27
  • Published : 2020.07.01
Download PDF
⟨ Previous Next ⟩

Abstract

Immunoglobulin G4-related disease (IgG4-RD) is a fibro-inflammatory condition characterized by several pathological features that can theoretically involve all organs. Ovarian involvement in IgG4-RD has been reported by two studies only. Herein, we report a pathologically confirmed case of ovarian involvement of IgG4-RD, which mimicked bilateral ovarian malignancies on computed tomography and magnetic resonance imaging.

면역글로불린 G4 관련 질환은 신체 전 장기를 침범할 수 있는 전신적인 섬유-염증성 질환이다. 면역글로불린 G4 관련 질환이 난소를 침범한 경우는 드물어서 현재까지 2건의 증례만이 보고되었다. 컴퓨터단층촬영 및 자기공명영상에서 양측 난소의 악성 종양으로 오인되었으나 병리학적으로 면역글로불린 G4 관련 질환으로 진단한 증례를 보고하고자 한다.

Keywords

Acknowledgement

This research was supported by the National Research Foundation of Korea grant funded by the Korean Government (NRF-2016R1D1A1B03935144).

References

  1. Deshpande V, Zen Y, Chan JK, Yi EE, Sato Y, Yoshino T, et al. Consensus statement on the pathology of IgG4-related disease. Mod Pathol 2012;25:1181-1192
  2. Carruthers MN, Khosroshahi A, Augustin T, Deshpande V, Stone JH. The diagnostic utility of serum IgG4 concentrations in IgG4-related disease. Ann Rheum Dis 2015;74:14-18
  3. Yu KH, Chan TM, Tsai PH, Chen CH, Chang PY. Diagnostic performance of serum IgG4 levels in patients with IgG4-related disease. Medicine (Baltimore) 2015;94:e1707
  4. Hao M, Liu M, Fan G, Yang X, Li J. Diagnostic value of serum IgG4 for IgG4-related disease: a PRISMA-compliant systematic review and meta-analysis. Medicine (Baltimore) 2016;95:e3785
  5. Zen Y, Nakanuma Y. IgG4-related disease: a cross-sectional study of 114 cases. Am J Surg Pathol 2010;34:1812-1819
  6. Maruyama S, Sato Y, Taga A, Emoto I, Shirase T, Haga H. Immunoglobulin G4-related disease presenting as bilateral ovarian masses and mimicking advanced ovarian cancer. J Obstet Gynaecol Res 2016;42:103-108
  7. Sekulic M, Pichler Sekulic S, Movahedi-Lankarani S. IgG4-related disease of the ovary: a first description. Int J Gynecol Pathol 2017;36:190-194