DOI QR코드

DOI QR Code

좌심방과 좌심방이의 전산화단층촬영 소견: 해부학, 정상변이 및 질환에 관한 임상화보

Computed Tomography of the Left Atrium and Left Atrial Appendage: A Pictorial Essay on the Anatomy, Normal Variants, and Pathology

  • 송민지 (충북대학교병원 영상의학과) ;
  • 김성진 (충북대학교병원 영상의학과) ;
  • 구현정 (울산대학교 의과대학 서울아산병원 영상의학과) ;
  • 김문영 (서울특별시보라매병원 영상의학과) ;
  • 유진영 (충북대학교병원 영상의학과)
  • Minji Song (Department of Radiology, Chungbuk National University Hospital) ;
  • Sung Jin Kim (Department of Radiology, Chungbuk National University Hospital) ;
  • Hyun Jung Koo (Department of Radiology and Research Institute of Radiology, Cardiac Imaging Center, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Moon Young Kim (Department of Radiology, SMG-SNU Boramae Medical Center) ;
  • Jin Young Yoo (Department of Radiology, Chungbuk National University Hospital)
  • 투고 : 2019.12.24
  • 심사 : 2020.03.19
  • 발행 : 2020.03.01

초록

전산화단층촬영(이하 CT) 영상 기술의 발전으로 박동하는 심장에 대한 섬세한 영상의학적 평가가 가능해졌다. 심초음파 및 MRI에 비해 심장 CT의 강점은 대부분의 의료기관에 보급되어 있고 고품질 이미지의 빠른 생산이 가능하며 해부학적 묘사가 뛰어나다는 것이다. 좌심방과 좌심방이에서 생기는 대부분의 변이 혹은 병리적 상태들은 CT 상의 소견만으로도 추정 진단을 내릴 수 있다. 또한 CT 영상은 성공적인 카테터 기반 시술 또는 수술에 중요한 해부학적 정보들을 제공한다. 특히 좌심방과 좌심방이는 심방세동 환자들의 치료 및 관리에 중요한데, 이는 다양한 카테터 기반 시술들이 두 구조물의 기계적 혹은 전기적 차단을 목표로 하기 때문이다. 따라서 임상적으로 의미 있는 판독을 위해서는 병리적 상태의 CT 소견 기술과 함께 좌심방 및 좌심방이의 모양, 크기 및 주변 구조물과의 상대적 위치 관계 등에 대한 포괄적인 검토를 해야 한다.

Current advances in CT techniques allow thorough evaluation of the beating heart. The strengths of cardiac CT relative to echocardiography and magnetic resonance imaging are its high availability in most institutions, rapid production of high-quality images, and outstanding delineation of the anatomy. For many normal variants and pathologic conditions, such as thrombi, masses, and congenital abnormalities of the left atrium, CT findings are sufficient to make a presumptive diagnosis. Assessments of the left atrium and left atrial appendage are particularly important for the management of atrial fibrillation, as various catheter-based procedures are aimed at the mechanical and electrical isolation of these structures. CT offers information crucial to a successful catheter-based procedure or surgery. Therefore, a comprehensive review of the geometry (shape, size, and relative position), along with various CT imaging features of pathologic states, should be provided in radiology reports to be of clinical value.

키워드

참고문헌

  1. Balli O, Aytemir K, Karcaaltincaba M. Multidetector CT of left atrium. Eur J Radiol 2012;81:e37-46 
  2. Lacomis JM, Ocak I, Knollmann F, Voigt A, Bazaaz R. Cardiac CT: electrophysiological applications. In Schoepf UJ, ed. CT of the heart. Contemporary medical imaging. Totowa: Humana Press 2019:531-552 
  3. Ho SY, Cabrera JA, Sanchez-Quintana D. Left atrial anatomy revisited. Circ Arrhythm Electrophysiol 2012;5:220-228 
  4. Barbero U, Ho SY. Anatomy of the atria. A road map to the left atrial appendage. Herzschrittmacherther Elektrophysiol 2017;28:347-354 
  5. Di Biase L, Natale A, Romero J. Thrombogenic and arrhythmogenic roles of the left atrial appendage in atrial fibrillation. Circulation 2018;138:2036-2050 
  6. Korsholm K, Jensen JM, Nielsen-Kudsk JE. Cardiac computed tomography for left atrial appendage occlusion: acquisition, analysis, advantages, and limitations. Interv Cardiol Clin 2018;7:229-242 
  7. Xu B, Betancor J, Sato K, Harb S, Abdur Rehman K, Patel K, et al. Computed tomography measurement of the left atrial appendage for optimal sizing of the Watchman device. J Cardiovasc Comput Tomogr 2018;12:50-55 
  8. Rajwani A, Nelson AJ, Shirazi MG, Disney PJS, Teo KSL, Wong DTL, et al. CT sizing for left atrial appendage closure is associated with favourable outcomes for procedural safety. Eur Heart J Cardiovasc Imaging 2017;18:1361-1368 
  9. Ismail TF, Panikker S, Markides V, Foran JP, Padley S, Rubens MB, et al. CT imaging for left atrial appendage closure: a review and pictorial essay. J Cardiovasc Comput Tomogr 2015;9:89-102 
  10. January CT, Wann LS, Calkins H, Chen LY, Cigarroa JE, Cleveland JC Jr, et al. 2019 AHA/ACC/HRS focused update of the 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society in collaboration with the Society of Thoracic Surgeons. Circulation 2019;140:e125-e151 
  11. Yaghi S, Chang AD, Akiki R, Collins S, Novack T, Hemendinger M, et al. The left atrial appendage morphology is associated with embolic stroke subtypes using a simple classification system: a proof of concept study. J Cardiovasc Comput Tomogr 2020;14:27-33 
  12. Thomas L, Abhayaratna WP. Left atrial reverse remodeling: mechanisms, evaluation, and clinical significance. JACC Cardiovasc Imaging 2017;10:65-77 
  13. Negishi K. Incremental predictive value of left atrial parameters over clinical risk scores for subsequent atrial fibrillation: function beyond size. JACC Cardiovasc Imaging 2019;12:990-992 
  14. Oliver W, Matthews G, Ayers CR, Garg S, Gupta S, Neeland IJ, et al. Factors associated with left atrial remodeling in the general population. Circ Cardiovasc Imaging 2017;10:e005047 
  15. Kuchynka P, Podzimkova J, Masek M, Lambert L, Cerny V, Danek B, et al. The role of magnetic resonance imaging and cardiac computed tomography in the assessment of left atrial anatomy, size, and function. Biomed Res Int 2015;2015:247865 
  16. Olsen FJ, Bertelsen L, De Knegt MC, Christensen TE, Vejlstrup N, Svendsen JH, et al. Multimodality cardiac imaging for the assessment of left atrial function and the association with atrial arrhythmias. Circ Cardiovasc Imaging 2016;9:e004947 
  17. Whitaker J, Rajani R, Chubb H, Gabrawi M, Varela M, Wright M, et al. The role of myocardial wall thickness in atrial arrhythmogenesis. Europace 2016;18:1758-1772 
  18. Shirani J, Alaeddini J. Structural remodeling of the left atrial appendage in patients with chronic non-valvular atrial fibrillation: implications for thrombus formation, systemic embolism, and assessment by transesophageal echocardiography. Cardiovasc Pathol 2000;9:95-101 
  19. Yu HT, Lee JS, Kim TH, Uhm JS, Joung B, Hong GR, et al. Advanced left atrial remodeling and appendage contractile dysfunction in women than in men among the patients with atrial fibrillation: potential mechanism for stroke. J Am Heart Assoc 2016;5:e003361 
  20. Hozawa M, Morino Y, Matsumoto Y, Tanaka R, Nagata K, Kumagai A, et al. 3D-computed tomography to compare the dimensions of the left atrial appendage in patients with normal sinus rhythm and those with paroxysmal atrial fibrillation. Heart Vessels 2018;33:777-785 
  21. Kosiuk J, Uhe T, Stegmann C, Ueberham L, Bertagnolli L, Dagres N, et al. Morphological determinators of platelet activation status in patients with atrial fibrillation. Int J Cardiol 2019;279:90-95 
  22. Kim IC, Chang HJ, Cho IJ, Shim CY, Hong GR, Heo JH, et al. Benefit of four-dimensional computed tomography derived ejection fraction of the left atrial appendage to predict thromboembolic risk in the patients with valvular heart disease. Korean Circ J 2019;49:173-180 
  23. Lazoura O, Ismail TF, Pavitt C, Lindsay A, Sriharan M, Rubens M, et al. A low-dose, dual-phase cardiovascular CT protocol to assess left atrial appendage anatomy and exclude thrombus prior to left atrial intervention. Int J Cardiovasc Imaging 2016;32:347-354 
  24. Pathan F, Hecht H, Narula J, Marwick TH. Roles of transesophageal echocardiography and cardiac computed tomography for evaluation of left atrial thrombus and associated pathology: a review and critical analysis. JACC Cardiovasc Imaging 2018;11:616-627 
  25. Yasuoka R, Kurita T, Kotake Y, Akaiwa Y, Hashiguchi N, Motoki K, et al. A novel method to estimate blood flow velocity in the left atrial appendage using enhanced computed tomography: role of Hounsfield unit density ratio at two distinct points within the left atrial appendage. Heart Vessels 2017;32:893-901 
  26. Kassop D, Donovan MS, Cheezum MK, Nguyen BT, Gambill NB, Blankstein R, et al. Cardiac masses on cardiac CT: a review. Curr Cardiovasc Imaging Rep 2014;7:9281 
  27. Malik SB, Kwan D, Shah AB, Hsu JY. The right atrium: gateway to the heart--anatomic and pathologic imaging findings. Radiographics 2015;35:14-31 
  28. Araoz PA, Mulvagh SL, Tazelaar HD, Julsrud PR, Breen JF. CT and MR imaging of benign primary cardiac neoplasms with echocardiographic correlation. Radiographics 2000;20:1303-1319 
  29. Kim AY, Kim JS, Yoon Y, Kim EJ. Multidetector computed tomography findings of a papillary fibroelastoma of the aortic valve: a case report. J Korean Med Sci 2010;25:809-812 
  30. Laura DM, Donnino R, Kim EE, Benenstein R, Freedberg RS, Saric M. Lipomatous atrial septal hypertrophy: a review of its anatomy, pathophysiology, multimodality imaging, and relevance to percutaneous interventions. J Am Soc Echocardiogr 2016;29:717-723 
  31. Chiles C, Woodard PK, Gutierrez FR, Link KM. Metastatic involvement of the heart and pericardium: CT and MR imaging. Radiographics 2001;21:439-449 
  32. Lichtenberger JP, Reynolds DA, Keung J, Keung E, Carter BW. Metastasis to the heart: a radiologic approach to diagnosis with pathologic correlation. AJR Am J Roentgenol 2016;207:764-772 
  33. I,sIk O, Akyuz M, AyIk MF, Levent E, Atay Y. Cor triatriatum sinister: a case series. Turk Kardiyol Dern Ars 2016;44:20-23 
  34. Nassar PN, Hamdan RH. Cor triatriatum sinistrum: classification and imaging modalities. Eur J Cardiovasc Med 2011;1:84-87 
  35. Malik A, Fram D, Mohani A, Fischerkeller M, Yekta A, Mohyuddin Y, et al. Cor triatriatum: a multimodality imaging approach. Can J Cardiol 2008;24:e19-20 
  36. Pizzino F, Khandheria B, Carerj S, Oreto G, Cusma-Piccione M, Todaro MC, et al. PFO: button me up, but wait … Comprehensive evaluation of the patient. J Cardiol 2016;67:485-492 
  37. Yasunaga D, Hamon M. MDCT of interatrial septum. Diagn Interv Imaging 2015;96:891-899 
  38. Holda MK, Krawczyk-Ozog A, Koziej M, Pawlik W, Sorysz D, Wszolek K, et al. Cardiac computed tomography compared with two-dimensional transesophageal echocardiography for the detection and assessment of atrial septal pouches. Int J Cardiovasc Imaging 2018;34:1305-1313 
  39. Mazur M, Jasinska KA, Walocha JA. The morphology, clinical significance and imaging methods of the atrial septal pouch: a critical review. Transl Res Anat 2018;13:7-11 
  40. Nicolay S, Salgado RA, Shivalkar B, Van Herck PL, Vrints C, Parizel PM. CT imaging features of atrioventricular shunts: what the radiologist must know. Insights Imaging 2016;7:119-129 
  41. Holda MK, Koziej M, Wszolek K, Pawlik W, Krawczyk-Ozog A, Sorysz D, et al. Left atrial accessory appendages, diverticula, and left-sided septal pouch in multi-slice computed tomography. Association with atrial fibrillation and cerebrovascular accidents. Int J Cardiol 2017;244:163-168 
  42. Terpenning S, White CS. Imaging pitfalls, normal anatomy, and anatomical variants that can simulate disease on cardiac imaging as demonstrated on multidetector computed tomography. Acta Radiol Short Rep 2015;4:2047981614562443 
  43. Lodhi AM, Nguyen T, Bianco C, Movahed A. Coumadin ridge: an incidental finding of a left atrial pseudotumor on transthoracic echocardiography. World J Clin Cases 2015;3:831-834 
  44. Okajima K, Imamura K, Kanda G, Shimane A. Left atrial anomalous muscular band detected by computed tomography before catheter ablation in a patient with atrial fibrillation. J Arrhythm 2015;31:64-65 
  45. Nnaoma C, Sandhu G, Sossou C, Vavilin I, Bustillo J, Garg A. A band that causes leaky valves: severe mitral regurgitation due to left atrial fibrous band-a case report and literature review. Case Rep Cardiol 2019;2019:2458569