Neonatal Medicine

  • 제27권3호
  • /
  • Pages.126-132
  • /
  • 2020
  • /
  • 2287-9412(pISSN)
  • /
  • 2287-9803(eISSN)
대한신생아학회 (The Korean Society of Neonatology)
권호 표지
DOI QR코드

DOI QR Code

Hearing Impairments in Preterm Infants: Factors Associated with Discrepancies between Screening and Confirmatory Test Results

  • Han, Jung Ho (Department of Pediatrics, Yonsei University College of Medicine) ;
  • Shin, Jeong Eun (Department of Pediatrics, Yonsei University College of Medicine) ;
  • Lee, Soon Min (Department of Pediatrics, Yonsei University College of Medicine) ;
  • Eun, Ho Seon (Department of Pediatrics, Yonsei University College of Medicine) ;
  • Park, Min Soo (Department of Pediatrics, Yonsei University College of Medicine) ;
  • Park, Kook In (Department of Pediatrics, Yonsei University College of Medicine)
  • 투고 : 2020.05.16
  • 심사 : 2020.05.29
  • 발행 : 2020.08.31
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Purpose: The aim of the study was to investigate risk factors of hearing impairments in preterm infants and analyze factors associated with discrepancies between neonatal hearing screening (NHS) and confirmatory test results. Methods: We analyzed the medical records of 352 preterm infants born at 23 to 32 weeks' gestational age (GA) who underwent both automated auditory brainstem response (aABR) and confirmatory ABR (cABR). Results: Mean GA, mean birth weight, the incidence of small for GA and cesarean section birth were significantly different between the pass and refer groups on aABR and the normal and abnormal groups of cABR. On univariate analysis, bronchopulmonary dysplasia (odds ratio [OR], 2.74; 95% confidence interval [CI], 1.00 to 7.48), intraventricular hemorrhage (OR, 7.02; 95% CI, 1.59 to 31.05), and use of furosemide (OR, 3.84; 95% CI, 1.38 to 10.73) were the factors related to refer results on aABR. Periventricular leukomalacia (PVL; OR, 4.00; 95% CI, 1.39 to 11.52) and use of vancomycin (OR, 2.86; 95% CI, 1.22 to 6.73) were associated with abnormal cABR. Twenty-five (7.9%) infants had discrepant aABR and cABR results, particularly males and those in whom vancomycin was used. Conclusion: PVL and use of vancomycin were confirmed as independent risk factors for hearing loss in infants born at less than 32 weeks' GA. Also, discrepancies between the screening and confirmatory test may occur, especially among male infants and those in whom vancomycin was used. The hearing of infants must be assessed more carefully in such groups regardless of NHS results.

키워드

참고문헌

  1. Hirvonen M, Ojala R, Korhonen P, Haataja P, Eriksson K, Gissler M, et al. Visual and hearing impairments after preterm birth. Pediatrics 2018;142:e20173888. https://doi.org/10.1542/peds.2017-3888
  2. Wroblewska-Seniuk K, Greczka G, Dabrowski P, Szyfter-Harris J, Mazela J. Hearing impairment in premature newborns: analysis based on the national hearing screening database in Poland. PLoS One 2017;12:e0184359. https://doi.org/10.1371/journal.pone.0184359
  3. Hille ET, Weisglas-Kuperus N, van Goudoever JB, Jacobusse GW, Ens-Dokkum MH, de Groot L, et al. Functional outcomes and participation in young adulthood for very preterm and very low birth weight infants: the Dutch Project on Preterm and Small for Gestational Age Infants at 19 years of age. Pediatrics 2007;120:e587-95. https://doi.org/10.1542/peds.2006-2407
  4. Bielecki I, Horbulewicz A, Wolan T. Risk factors associated with hearing loss in infants: an analysis of 5282 referred neonates. Int J Pediatr Otorhinolaryngol 2011;75:925-30. https://doi.org/10.1016/j.ijporl.2011.04.007
  5. Robertson CM, Howarth TM, Bork DL, Dinu IA. Permanent bilateral sensory and neural hearing loss of children after neonatal intensive care because of extreme prematurity: a thirty-year study. Pediatrics 2009;123:e797-807. https://doi.org/10.1542/peds.2008-2531
  6. Wang CH, Yang CY, Lien R, Chu SM, Hsu JF, Fu RH, et al. Prevalence and independent risk factors for hearing impairment among very low birth weight infants. Int J Pediatr Otorhinolaryngol 2017;93:123-7. https://doi.org/10.1016/j.ijporl.2016.12.029
  7. Escobar-Ipuz FA, Soria-Bretones C, Garcia-Jimenez MA, Cueto EM, Torres Aranda AM, Sotos JM. Early detection of neonatal hearing loss by otoacoustic emissions and auditory brainstem response over 10 years of experience. Int J Pediatr Otorhinolaryngol 2019;127:109647. https://doi.org/10.1016/j.ijporl.2019.109647
  8. American Academy of Pediatrics, Joint Committee on Infant Hearing. Year 2007 position statement: principles and guidelines for early hearing detection and intervention programs. Pediatrics 2007;120:898-921. https://doi.org/10.1542/peds.2007-2333
  9. Kuki S, Chadha S, Dhingra S, Gulati A. The role of current audiological tests in the early diagnosis of hearing impairment in infant. Indian J Otolaryngol Head Neck Surg 2013;65:244-50. https://doi.org/10.1007/s12070-012-0558-x
  10. Humphrey C, Veve MP, Walker B, Shorman MA. Long-term vancomycin use had low risk of ototoxicity. PLoS One 2019; 14:e0224561. https://doi.org/10.1371/journal.pone.0224561
  11. Wang LA, Smith PB, Laughon M, Goldberg RN, Ku LC, Zimmerman KO, et al. Prolonged furosemide exposure and risk of abnormal newborn hearing screen in premature infants. Early Hum Dev 2018;125:26-30. https://doi.org/10.1016/j.earlhumdev.2018.08.009
  12. Hrncic N. Identification of risk factors for hearing impairment in newborns: a hospital based study. Med Glas (Zenica) 2018;15:29-36.
  13. van Dommelen P, Verkerk PH, van Straaten HL; Dutch Neonatal Intensive Care Unit Neonatal Hearing Screening Working Group. Hearing loss by week of gestation and birth weight in very preterm neonates. J Pediatr 2015;166:840-3. https://doi.org/10.1016/j.jpeds.2014.12.041
  14. Kraft CT, Malhotra S, Boerst A, Thorne MC. Risk indicators for congenital and delayed-onset hearing loss. Otol Neurotol 2014;35:1839-43. https://doi.org/10.1097/MAO.0000000000000615
  15. Eras Z, Konukseven O, Aksoy HT, Canpolat FE, Genc A, Sakrucu ED, et al. Postnatal risk factors associated with hearing loss among high-risk preterm infants: tertiary center results from Turkey. Eur Arch Otorhinolaryngol 2014;271:1485-90. https://doi.org/10.1007/s00405-013-2653-3
  16. Ohl C, Dornier L, Czajka C, Chobaut JC, Tavernier L. Newborn hearing screening on infants at risk. Int J Pediatr Otorhinolaryngol 2009;73:1691-5. https://doi.org/10.1016/j.ijporl.2009.08.027
  17. Joint Committee on Infant Hearing; American Academy of Audiology; American Academy of Pediatrics; American Speech-Language-Hearing Association; Directors of Speech and Hearing Programs in State Health and Welfare Agencies. Year 2000 position statement: principles and guidelines for early hearing detection and intervention programs. Pediatrics 2000;106:798-817. https://doi.org/10.1542/peds.106.4.798
  18. Jackson W, Taylor G, Selewski D, Smith PB, Tolleson-Rinehart S, Laughon MM. Association between furosemide in premature infants and sensorineural hearing loss and nephrocalcinosis: a systematic review. Matern Health Neonatol Perinatol 2018;4:23. https://doi.org/10.1186/s40748-018-0092-2
  19. Rybak LP, Whitworth C, Weberg A, Scott V. Effects of organic acids on the edema of the stria vascularis induced by furosemide. Hear Res 1992;59:75-84. https://doi.org/10.1016/0378-5955(92)90104-U
  20. Cristobal R, Oghalai JS. Hearing loss in children with very low birth weight: current review of epidemiology and pathophysiology. Arch Dis Child Fetal Neonatal Ed 2008;93:F462-8. https://doi.org/10.1136/adc.2007.124214
  21. Hille ET, van Straaten HI, Verkerk PH; Dutch NICU Neonatal Hearing Screening Working Group. Prevalence and independent risk factors for hearing loss in NICU infants. Acta Paediatr 2007;96:1155-8. https://doi.org/10.1111/j.1651-2227.2007.00398.x
  22. Gray PH, Sarkar S, Young J, Rogers YM. Conductive hearing loss in preterm infants with bronchopulmonary dysplasia. J Paediatr Child Health 2001;37:278-82. https://doi.org/10.1046/j.1440-1754.2001.00690.x
  23. Gilles FH, Leviton A. Neonatal white matter damage and the fetal inflammatory response. Semin Fetal Neonatal Med 2020 Apr 9 [Epub]. https://doi.org/10.1016/j.siny.2020.101111.
  24. Marret S, Vanhulle C, Laquerriere A. Pathophysiology of cerebral palsy. Handb Clin Neurol 2013;111:169-76. https://doi.org/10.1016/B978-0-444-52891-9.00016-6
  25. Zhang Z, Jia X, Guan X, Zhang Y, Lyu Y, Yang J, et al. White matter abnormalities of auditory neural pathway in sudden sensorineural hearing loss using diffusion spectrum imaging: different findings from tinnitus. Front Neurosci 2020;14:200. https://doi.org/10.3389/fnins.2020.00200
  26. Kim SY, Choi BY, Jung EY, Park H, Yoo HN, Park KH. Risk factors for failure in the newborn hearing screen test in very preterm twins. Pediatr Neonatol 2018;59:586-94. https://doi.org/10.1016/j.pedneo.2018.01.014
  27. Lauer AM, Schrode KM. Sex bias in basic and preclinical noise-induced hearing loss research. Noise Health 2017;19:207-12. https://doi.org/10.4103/nah.NAH_12_17