참고문헌
- Moore WR, Anderson ME, Meister A, Murata K and Kimura A (1989) Increased capacity for glutathione synthesis enhances resistance to radiation in Escherichia coli: a possible model for mammalian cell protection. Proc Natl Acad Sci U S A 86, 1461-1464 https://doi.org/10.1073/pnas.86.5.1461
- Godwin AK, Meister A, O'Dwyer PJ, Huang CS, Hamilton TC and Anderson ME (1992) High resistance to cisplatin in human ovarian cancer cell lines is associated with marked increase of glutathione synthesis. Proc Natl Acad Sci U S A 89, 3070-3074 https://doi.org/10.1073/pnas.89.7.3070
- Shin SY, Lee JM, Lee MS et al (2014) Targeting cancer cells via the reactive oxygen species-mediated unfolded protein response with a novel synthetic polyphenol conjugate. Clin Cancer Res 20, 4302-4313 https://doi.org/10.1158/1078-0432.CCR-14-0424
- Adams DJ, Dai M, Pellegrino G et al (2012) Synthesis, cellular evaluation, and mechanism of action of piperlongumine analogs. Proc Natl Acad Sci U S A 109, 15115-15120 https://doi.org/10.1073/pnas.1212802109
- Cho HY, Thomas S, Golden EB et al (2009) Enhanced killing of chemo-resistant breast cancer cells via controlled aggravation of ER stress. Cancer Lett 282, 87-97 https://doi.org/10.1016/j.canlet.2009.03.007
- Boatright KM and Salvesen GS (2003) Mechanisms of caspase activation. Curr Opin Cell Biol 15, 725-731 https://doi.org/10.1016/j.ceb.2003.10.009
- Harker WG and Sikic BI (1985) Multidrug (pleiotropic) resistance in doxorubicin-selected variants of the human sarcoma cell line MES-SA. Cancer Res 45, 4091-4096
- Miura YH, Tomita I, Watanabe T, Hirayama T and Fukui S (1998) Active oxygens generation by flavonoids. Biol Pharm Bull 21, 93-96 https://doi.org/10.1248/bpb.21.93
- Gaspar J, Rodrigues A, Laires A et al (1994) On the mechanisms of genotoxicity and metabolism of quercetin. Mutagenesis 9, 445-449 https://doi.org/10.1093/mutage/9.5.445
- Luo H, Yang A, Schulte BA, Wargovich MJ and Wang GY (2013) Resveratrol induces premature senescence in lung cancer cells via ROS-mediated DNA damage. PLoS One 8, e60065 https://doi.org/10.1371/journal.pone.0060065
- Basu S, Ganguly A, Chakraborty P et al (2012) Targeting the mitochondrial pathway to induce apoptosis/necrosis through ROS by a newly developed Schiff's base to overcome MDR in cancer. Biochimie 94, 166-183 https://doi.org/10.1016/j.biochi.2011.10.004
- Lee DH, Jung Jung Y, Koh D, Lim Y, Lee YH and Shin SY (2016) A synthetic chalcone, 2'-hydroxy-2,3,5'-trimethoxychalcone triggers unfolded protein response-mediated apoptosis in breast cancer cells. Cancer Lett 372, 1-9 https://doi.org/10.1016/j.canlet.2015.12.017
- Uemura A, Oku M, Mori K and Yoshida H (2009) Unconventional splicing of XBP1 mRNA occurs in the cytoplasm during the mammalian unfolded protein response. J Cell Sci 122, 2877-2886 https://doi.org/10.1242/jcs.040584
- Yoshida H, Matsui T, Yamamoto A, Okada T and Mori K (2001) XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell 107, 881-891 https://doi.org/10.1016/S0092-8674(01)00611-0
- Szegezdi E, Logue SE, Gorman AM and Samali A (2006) Mediators of endoplasmic reticulum stress-induced apoptosis. EMBO Rep 7, 880-885 https://doi.org/10.1038/sj.embor.7400779
- Puthalakath H, O'Reilly LA, Gunn P et al (2007) ER stress triggers apoptosis by activating BH3-only protein Bim. Cell 129, 1337-1349 https://doi.org/10.1016/j.cell.2007.04.027
- O'Connor L, Strasser A, O'Reilly LA et al (1998) Bim: a novel member of the Bcl-2 family that promotes apoptosis. EMBO J 17, 384-395 https://doi.org/10.1093/emboj/17.2.384
- Cao L, Wan Q, Li F and Tang Ce (2018) MiR-363 inhibits cisplatin chemoresistance of epithelial ovarian cancer by regulating snail-induced epithelial-mesenchymal transition. BMB Rep 51, 456-461 https://doi.org/10.5483/BMBRep.2018.51.9.104
- Shin SY, Yoon H, Ahn S et al (2013) Structural Properties of Polyphenols Causing Cell Cycle Arrest at G1 Phase in HCT116 Human Colorectal Cancer Cell Lines. Int J Mol Sci 14, 16970-16985 https://doi.org/10.3390/ijms140816970
- Shin SY, Yoon H, Ahn S et al (2013) Chromenylchalcones showing cytotoxicity on human colon cancer cell lines and in silico docking with aurora kinases. Bioorg Med Chem 21, 4250-4258 https://doi.org/10.1016/j.bmc.2013.04.086
- Shin SY, Lee KS, Choi YK et al (2013) The antipsychotic agent chlorpromazine induces autophagic cell death by inhibiting the Akt/mTOR pathway in human U-87MG glioma cells. Carcinogenesis 34, 2080-2089 https://doi.org/10.1093/carcin/bgt169
- Gil HN, Koh D, Lim Y, Lee YH and Shin SY (2018) The synthetic chalcone derivative 2-hydroxy-3',5,5'-trimethoxychalcone induces unfolded protein response-mediated apoptosis in A549 lung cancer cells. Bioorg Med Chem Lett 28, 2969-2975 https://doi.org/10.1016/j.bmcl.2018.07.003
- Calfon M, Zeng H, Urano F et al (2002) IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA. Nature 415, 92-96 https://doi.org/10.1038/415092a