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Effect of Macleaya cordata and Magnolia officinalis plant extracts on oxidative stress control in lambs fed a high-concentrate diet

  • Received : 2019.01.15
  • Accepted : 2019.06.04
  • Published : 2020.06.01

Abstract

Objective: The objective of this experiment was to compare conventional antioxidants and plant extracts for oxidative stress control in lambs fed a high-concentrate diet. Methods: Forty-eight male Dorper×Santa Ines lambs with an initial weight of 20±1.49 kg and 60 days of age, were used to evaluate the effects of feeding a combination of Macleaya cordata and Magnolia officinalis plant extracts (0 vs 320 mg/kg dry matter [DM]) in combination with selenium+vitamin E (0 vs 100 IU/kg DM of vitamin E and 0.1 mg/kg DM of selenium) in a completely randomized block design in a 2×2 factorial arrangement. The animals were housed in individual pens and received a high-concentrate diet consisting of 80% whole corn and 20% protein pellet for 60 days. The animals were weighed at the beginning of the experiment and every 14 days for performance monitoring. Three blood samplings were performed during the experimental period for the evaluation of oxidative and protein parameters. Results: The treatments with vitamin E and selenium as additives had a positive influence on final weight, daily weight gain, carcass weight, and selenium content in longissimus muscle (p = 0.01). Plant extracts tended to improve final weight (p = 0.064) and daily weight gain (p = 0.059), showing similar effect as selenium and vitamin E. There was no effect of treatment on blood proteins, indicating that the animals were healthy throughout the experiment. Conclusion: The use of plant extracts had a similar effect as the addition of selenium and vitamin E, with dietary inclusion of additives resulting in better performance of lambs but both supplements did not have strong influence on oxidative stress.

Keywords

References

  1. Gallo SB, Merlin FA, Macedo CM, Silveira RDO. Whole grain diet for feedlot lambs. Small Rumin Res 2014;120:185-8. https://doi.org/10.1016/j.smallrumres.2014.05.014
  2. Cirne LGA, Oliveira GJC, Jaeger SMPL, et al. Performance of feedlot lambs feed with exclusive concentrate diet with different percentages of protein. Braz J Vet Res Anim Sci 2013;65:262-6. http://dx.doi.org/10.1590/S0102-09352013000100037
  3. Celi P. The role of oxidative stress in small ruminants' health and production. Braz J Anim Sci, 2010;39(Suppl. spe):348-63. https://dx.doi.org/10.1590/S1516-35982010001300038
  4. Mukherjee R. Selenium and vitamin E increases polymorphonuclear cell phagocytosis and antioxidant levels during acute mastitis in riverine buffaloes. Vet Res Commun 2008; 32:305-13. https://doi.org/10.1007/s11259-007-9031-9
  5. Hogan JS, Smith KL, Weiss WP, Todhunter DA, Schockey WL. Relationships among vitamin E, selenium, and bovine blood neutrophils. J Dairy Sci 1990;73:2372-8. https://doi.org/10.3168/jds.S0022-0302(90)78920-5
  6. Bang KH, Kim YK, Min BS, et al. Antifungal activity of magnolol and honokiol. Arch Pharm Res 2000;23:46-9. https://doi.org/10.1007/BF02976465
  7. Bai X, Cerimele F, Ushio-Fukai M, et al. Honokiol, a small molecular weight natural product, inhibits angiogenesis in vitro and tumor growth in vivo. J Biol Chem 2003;278:35501-7. https://doi.org/10.1074/jbc.M302967200
  8. Park J, Lee J, Jung E, et al. In vitro antibacterial and anti-inflammatory effects of honokiol and magnolol against Propionibacterium sp. Eur J Pharmacol 2004;496:189-95. https://doi.org/10.1016/j.ejphar.2004.05.047
  9. Kim BH, Cho JY. Anti-inflammatory effect of honokiol is mediated by PI3K/Akt pathway suppression. Acta Pharmacol Sin 2008;29:113-22. https://doi.org/10.1111/j.1745-7254.2008.00725.x
  10. Association of Official Agricultural Chemists. Official methods of analysis of AOAC International. 16th ed. Arlington, VA, USA: AOAC International; 1995.
  11. Weiss WP, Conrad HR, Pierre RRS. A theoretically - based model for predicting total digestible nutrient values of forages and concentrates. Anim Feed Sci Technol 1992;39:95-110. https://doi.org/10.1016/0377-8401(92)90034-4
  12. Olson OE, Palmer IS, Cary EE. Modification of the official fluorometric method for selenium in plants. J Assoc Off Agric Chem 1975;58:117-21.
  13. National Research Council (NRC). Nutrient requirements of small ruminants: sheep, goats, cervids and new world camelids, 6th ed. Washington, DC, USA: National Academy Press; 2007.
  14. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970;227: 680-5. https://doi.org/10.1038/227680a0
  15. American Meat Science Association (AMSA). Research guidelines for cookery, sensory evaluation, and instrumental tenderness measurements of fresh meat. Chicago, IL, USA: American Meat Science Association (AMSA) & National Live Stock and Meat Board; 1995.
  16. Bigham ML, McManaus WR. Whole wheat grain feeding of lambs. 5. Effects of roughage and wheat grain mixtures. Aust J Agric Res 1975;26:1053-62. https://doi.org/10.1071/AR9751053
  17. Resende Junior JC, Alonso LS, Pereira MN, et al. Effect of the feeding pattern on rumen wall morphology of cows and sheep. Braz J Vet Res Anim Sci 2006;43:526-36. https://doi.org/10.11606/issn.1678-4456.bjvras.2006.26469
  18. Kumar N, Garg AK, Mudgal V, Dass RS, Chaturvedi VK, Varshney VP. Effect of different levels of selenium supplementation on growth rate, nutrient utilization, blood metabolic profile, and immune response in lambs. Biol Trace Elem Res 2008;126:44-56. https://doi.org/10.1007/s12011-008-8214-8
  19. Urano FS, Pires AV, Susin I, et al. Performance and carcass characteristics of feedlot lambs fed raw soybean. Braz J Agric Res 2006;41:1525-30. http://dx.doi.org/10.1590/S0100-204X 2006001000010
  20. Cezar MF, Souza WH. Ovine and caprine carcasses: generation, evaluation and classification. Uberaba, MG, Brazil: Ed. Agropecuaria Tropical; 2007. 231 p.
  21. Coles EH, Meyer DJ, Rich LJ. Veterinary laboratory medicine: interpretation and diagnosis. Philadelphia, PA, USA: Saunders; 1992.
  22. Kaneko J, Harvey J, Bruss M. Clinical biochemistry of domestic animals. 5th ed. New York, USA: Academic Press; 1997.
  23. Tothova C, Nagy O, Kovac G. Acute phase proteins and their use in the diagnosis of diseases in ruminants: a review. Vet Med 2014;59:163-80. https://doi.org/10.17221/7478-vetmed
  24. Ceciliani F, Ceron JJ, Eckersall PD, Sauerwein H. Acute phase proteins in ruminants. J Proteomics 2012;75:4207-31. https://doi.org/10.1016/j.jprot.2012.04.004
  25. Gruys E, Toussaint MJM, Niewold TA, Koopmans SJ. Acute phase reaction and acute phase proteins. J Zhejiang Univ Sci B 2005;6:1045-56. https://doi.org/10.1631/jzus.2005.B1045
  26. Esmaeilnejad B, Tavassoli M, Asri-Rezaei S, et al. Evaluation of antioxidant status, oxidative stress and serum trace mineral levels associated with Babesia ovis parasitemia in sheep. Vet Parasitol 2014;205:38-45. https://doi.org/10.1016/j.vetpar.2014. 07.005
  27. Rezaei SA, Dalir-Naghadeh B. Association of plasma and heart homocysteine and blood malondialdehyde with cardiovascular diseases induced by acute selenium deficiency in lambs. Small Rumin Res 2009;83:22-8. https://doi.org/10.1016/j.smallrumres.2009.02.006
  28. Kumar N, Garg AK, Dass RS, Chaturvedi VK, Mudgal V, Varshney VP. Selenium supplementation influences growth performance, antioxidant status and immune response in lambs. Anim Feed Sci Technol 2009;153:77-87. https://doi.org/10.1016/j.anifeedsci.2009.06.007
  29. Nunes RCA, Viana RS, Neto NBM. Superoxide dismutase enzyme activity in response to plant hormones in Gerbera jamensonii. Comun Sci 2015;6:83-9.