Journal of Digestive Cancer Research

Korean Society of Gastrointestinal Cancer Research (대한소화기암연구학회)
권호 표지

Aspirin and Non-steroidal Anti-inflammatory Drugs in Prevention of Gastric Cancer

아스피린 및 비스테로이드 소염제와 위암의 예방

  • Kim, Yeon-Ji (Department of Internal Medicine, St. Vincent's Hospital, The Catholic University of Korea College of Medicine) ;
  • Chung, Woo Chul (Department of Internal Medicine, St. Vincent's Hospital, The Catholic University of Korea College of Medicine)
  • 김연지 (가톨릭대학교 의과대학 내과학교실 성빈센트병원 소화기내과) ;
  • 정우철 (가톨릭대학교 의과대학 내과학교실 성빈센트병원 소화기내과)
  • Received : 2020.10.21
  • Accepted : 2020.11.16
  • Published : 2020.12.31

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Abstract

Gastric cancer is one of the leading causes of cancer-related deaths worldwide. The increased expression of cyclooxygenase (COX)-2 has been implicated in the development and progression of gastric cancers. A number of recent studies have been published evaluating the chemopreventive effect of aspirin and non steroidal anti inflammatory drungs (NSAIDs) against gastric cancer. Aspirin and NSAIDs use may reduce the risk of gastric cancer incidence and death, whereas other studies have reported contradictory results. Therefore, further study should be needed to clarify the role of aspirin and NSAIDs in the chemoprevention of gastric cancer.

Keywords

References

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