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Audiogram in Response to Stimulation Delivered to Fluid Applied to the External Meatus

  • Geal-Dor, Miriam (Speech & Hearing Center, Hadassah University Medical Center) ;
  • Chordekar, Shai (Speech & Hearing Center, Hadassah University Medical Center) ;
  • Adelman, Cahtia (Speech & Hearing Center, Hadassah University Medical Center) ;
  • Kaufmann-Yehezkely, Michal (Department of Otorhinolaryngology/Head & Neck Surgery, Hadassah University Medical Center) ;
  • Sohmer, Haim (Department of Medical Neurobiology, Hebrew University-Hadassah Medical School)
  • 투고 : 2019.10.07
  • 심사 : 2019.12.23
  • 발행 : 2020.04.20

초록

Background and Objectives: Hearing can be elicited in response to vibratory stimuli delivered to fluid in the external auditory meatus. To obtain a complete audiogram in subjects with normal hearing in response to pure tone vibratory stimuli delivered to fluid applied to the external meatus. Subjects and Methods: Pure tone vibratory stimuli in the audiometric range from 0.25 to 6.0 kHz were delivered to fluid applied to the external meatus of eight participants with normal hearing (15 dB or better) using a rod attached to a standard clinical bone vibrator. The fluid thresholds obtained were compared to the air conduction (AC), bone conduction (BC; mastoid), and soft tissue conduction (STC; neck) thresholds in the same subjects. Results: Fluid stimulation thresholds were obtained at every frequency in each subject. The fluid and STC (neck) audiograms sloped down at higher frequencies, while the AC and BC audiograms were flat. It is likely that the fluid stimulation audiograms did not involve AC mechanisms or even, possibly, osseous BC mechanisms. Conclusions: The thresholds elicited in response to the fluid in the meatus likely reflect a form of STC and may result from excitation of the inner ear by the vibrations induced in the fluid. The sloping fluid audiograms may reflect transmission pathways that are less effective at higher frequencies.

키워드

과제정보

The participation of Miriam Geal-Dor was supported by the Newman Fund for audiological research. We would like to thank the Newman Fund for audiological research (The fund had no involvement in the study design, in the collection, analysis, and interpretation of data; in the writing of the manuscript; and in the decision to submit the manuscript for publication).

참고문헌

  1. Ravicz ME, Melcher JR. Isolating the auditory system from acoustic noise during functional magnetic resonance imaging: examination of noise conduction through the ear canal, head, and body. J Acoust Soc Am 2001;109:216-31. https://doi.org/10.1121/1.1326083
  2. Berger EH, Kieper RW, Gauger D. Hearing protection: surpassing the limits to attenuation imposed by the bone-conduction pathways. J Acoust Soc Am 2003;114:1955-67. https://doi.org/10.1121/1.1605415
  3. Kaufmann M, Adelman C, Sohmer H. Mapping at sites on bone and soft tissue on the head, neck and thorax at which a bone vibrator elicits auditory sensation. Audiol Neurotol Extra 2012;2:9-15. https://doi.org/10.1159/000336159
  4. Adelman C, Yehezkely MK, Chordekar S, Sohmer H. Relation between body structure and hearing during soft tissue auditory stimulation. Biomed Res Int 2015;2015:172026. https://doi.org/10.1155/2015/172026
  5. Sohmer H. Soft tissue conduction: review, mechanisms, and implications. Trends Hear 2017;21:2331216517734087.
  6. Sim JH, Dobrev I, Gerig R, Pfiffner F, Stenfelt S, Huber AM, et al. Interaction between osseous and non-osseous vibratory stimulation of the human cadaveric head. Hear Res 2016;340:153-60. https://doi.org/10.1016/j.heares.2016.01.013
  7. Chordekar S, Perez R, Adelman C, Sohmer H, Kishon-Rabin L. Does hearing in response to soft-tissue stimulation involve skull vibrations? A within-subject comparison between skull vibration magnitudes and hearing thresholds. Hear Res 2018;364:59-67. https://doi.org/10.1016/j.heares.2018.03.030
  8. Ronen O, Geal-Dor M, Kaufmann-Yehezkely M, Perez R, Chordekar S, Adelman C, et al. Inner ear excitation in normal and postmastoidectomy participants by fluid stimulation in the absence of air- and bone-conduction mechanisms. J Am Acad Audiol 2017;28:152-60. https://doi.org/10.3766/jaaa.16036
  9. Perez R, Adelman C, Sohmer H. Fluid stimulation elicits hearing in the absence of air and bone conduction--an animal study. Acta Otolaryngol 2016;136:351-3. https://doi.org/10.3109/00016489.2015.1113560
  10. Adelman C, Sohmer H. Thresholds to soft tissue conduction stimulation compared to bone conduction stimulation. Audiol Neurootol 2013;18:31-5. https://doi.org/10.1159/000342823
  11. Oghalai JS. The cochlear amplifier: augmentation of the traveling wave within the inner ear. Curr Opin Otolaryngol Head Neck Surg 2004;12:431-8. https://doi.org/10.1097/01.moo.0000134449.05454.82
  12. de Jong M, Perez R, Adelman C, Chordekar S, Rubin M, Kriksunov L, et al. Experimental confirmation that vibrations at soft tissue conduction sites induce hearing by way of a new mode of auditory stimulation. J Basic Clin Physiol Pharmacol 2011;22:55-8. https://doi.org/10.1515/JBCPP.2011.014
  13. Adelman C, Fraenkel R, Kriksunov L, Sohmer H. Interactions in the cochlea between air conduction and osseous and non-osseous bone conduction stimulation. Eur Arch Otorhinolaryngol 2012;269:425-9. https://doi.org/10.1007/s00405-011-1640-9
  14. Stenfelt S, Goode RL. Bone-conducted sound: physiological and clinical aspects. Otol Neurotol 2005;26:1245-61. https://doi.org/10.1097/01.mao.0000187236.10842.d5
  15. Stenfelt S. Acoustic and physiologic aspects of bone conduction hearing. Adv Otorhinolaryngol 2011;71:10-21.
  16. Tonndorf J. Bone conduction. Studies in experimental animals. Acta Otolaryngol 1966;Suppl 213:1-132.
  17. Yehezkely MK, Grinblat G, Dor MG, Chordekar S, Perez R, Adelman C, et al. Implications for bone conduction mechanisms from thresholds of post radical mstoidectomy and subtotal petrosectomy patients. J Int Adv Otol 2019;15:8-11. https://doi.org/10.5152/iao.2019.6268
  18. Wever EG, Lawrence M. The function of the middle ear. In: Wever EG, Lawrence M, editors. Physiological Acoustics Princeton. Princeton, NJ: Princeton University Press;1954. p.69-78.
  19. Baun J. Interaction with soft tissue. In: Baun J, editor. Physical Principles of General and Vascular Sonography. San Francisco, CA:ProSono Publishing;2004. p.28-41.
  20. Perez R, Adelman C, Sohmer H. Bone conduction activation through soft tissues following complete immobilization of the ossicular chain, stapes footplate and round window. Hear Res 2011;280:82-5. https://doi.org/10.1016/j.heares.2011.04.007
  21. Perez R, Adelman C, Chordekar S, Ishai R, Sohmer H. Air, bone and soft tissue excitation of the cochlea in the presence of severe impediments to ossicle and window mobility. Eur Arch Otorhinolaryngol 2015;272:853-60. https://doi.org/10.1007/s00405-014-2887-8
  22. Tabuchi K, Murashita H, Okubo H, Takahashi K, Wada T, Hara A. Preoperative evaluation of ossicular chain abnormality in patients with conductive deafness without perforation of the tympanic membrane. Arch Otolaryngol Head Neck Surg 2005;131:686-9. https://doi.org/10.1001/archotol.131.8.686
  23. Nishimura T, Hosoi H, Saito O, Miyamae R, Shimokura R, Yamanaka T, et al. Cartilage conduction is characterized by vibrations of the cartilaginous portion of the ear canal. PLoS One 2015;10:e0120135. https://doi.org/10.1371/journal.pone.0120135