The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
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A Case Report of Korean Medicine Treatment of Non-small Cell Lung Cancer with Pleural Metastasis Following Targeted Chemotherapy with Afatinib

Afatinib 표적항암치료를 시행 중인 흉막 전이된 비소세포폐암 환자의 한방치료 증례보고

  • Kim, Kyun Ha (National Clinical Research Center for Korean Medicine, Korean Medicine Hospital of Pusan National University) ;
  • Kang, Hee-kyung (Dept. of Korean Internal Medicine, Korean Medicine Hospital of Pusan National University) ;
  • Kim, So-yeon (Dept. of Korean Internal Medicine, Korean Medicine Hospital of Pusan National University) ;
  • Han, Chang-woo (Dept. of Korean Internal Medicine, Korean Medicine Hospital of Pusan National University) ;
  • Park, Seong-ha (Dept. of Korean Internal Medicine, Korean Medicine Hospital of Pusan National University) ;
  • Yun, Young-ju (Dept. of Korean Internal Medicine, Korean Medicine Hospital of Pusan National University) ;
  • Lee, In (Dept. of Korean Internal Medicine, Korean Medicine Hospital of Pusan National University) ;
  • Kwon, Jung-nam (Dept. of Korean Internal Medicine, Korean Medicine Hospital of Pusan National University) ;
  • Hong, Jin-woo (Dept. of Korean Internal Medicine, Korean Medicine Hospital of Pusan National University) ;
  • Choi, Jun-Yong (National Clinical Research Center for Korean Medicine, Korean Medicine Hospital of Pusan National University)
  • 김균하 (부산대한방병원 한의약임상연구센터) ;
  • 강희경 (부산대학교한방병원 한방내과) ;
  • 김소연 (부산대학교한방병원 한방내과) ;
  • 한창우 (부산대학교한방병원 한방내과) ;
  • 박성하 (부산대학교한방병원 한방내과) ;
  • 윤영주 (부산대학교한방병원 한방내과) ;
  • 이인 (부산대학교한방병원 한방내과) ;
  • 권정남 (부산대학교한방병원 한방내과) ;
  • 홍진우 (부산대학교한방병원 한방내과) ;
  • 최준용 (부산대한방병원 한의약임상연구센터)
  • Received : 2020.11.13
  • Accepted : 2020.12.23
  • Published : 2020.12.30
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Abstract

Objective: The purpose of this study was to report the effect of Korean medicine on a patient with non-small cell lung cancer with pleural metastasis who had been treated with afatinib. Method: A 61-year old female patient with non-small cell lung cancer with pleural metastasis was treated with acupuncture and herbal medicines, including Yijung-tang, Haengso-tang, Samchulkunbi-tang, Paeamju-bang (Feiai zhu fang), to control various symptoms caused by afatinib. The degree of pain was assessed by a numeric rating scale (NRS) and the quality of life was determined with the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire, Core 30 (EORTC QLQ-C30) and the EORTC 13-item lung cancer-specific module (EORTC LC-13). Results: After receiving acupuncture and herbal medicines, the patient showed improvement in her back and chest pain, according to the NRS score. Similarly, the Korean medicinal treatments significantly relieved her nausea, vomiting, diarrhea, hemoptysis, and alopecia. However, the EORTC QLQ-C30 assessment suggested that Korean medicinal treatments did not significantly improve the global health status of this patient. Conclusion: Korean medicine could be useful in relieving some of the symptoms occurring after conventional afatinib treatments.

Keywords

References

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