한국동물위생학회지 (Korean Journal of Veterinary Service)

  • 제43권4호
  • /
  • Pages.245-250
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  • 2020
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  • 3022-7372(pISSN)
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  • 2287-7630(eISSN)
한국동물위생학회 (The Korean Society of Veterinary Service)
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Hematological and microbial analysis on a Holstein heifer with infectious bovine keratoconjunctivitis

  • Ha, Seungmin (Department of Animal Resources Development, National Institute of Animal Science) ;
  • Hur, Taiyoung (Department of Animal Resources Development, National Institute of Animal Science) ;
  • Kang, Seogjin (Rural Development Administration) ;
  • Jung, Younghun (Department of Animal Resources Development, National Institute of Animal Science) ;
  • Son, Junkyu (Department of Animal Resources Development, National Institute of Animal Science) ;
  • Kim, Donghyeon (Department of Animal Resources Development, National Institute of Animal Science) ;
  • Lee, Jihwan (Department of Animal Resources Development, National Institute of Animal Science) ;
  • Sung, Hyunhoon (Department of Animal Resources Development, National Institute of Animal Science) ;
  • Cho, Eunseok (Department of Animal Resources Development, National Institute of Animal Science) ;
  • Kim, Sangbeom (Rural Development Administration)
  • 투고 : 2019.12.06
  • 심사 : 2020.12.22
  • 발행 : 2020.12.30
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초록

Infectious bovine keratoconjunctivitis (IBK) is the most common ocular disease in cattle, manifesting as corneal opacity, corneal ulcerations and potentially vision loss. The present report describes a 10-month-old Holstein Friesian heifer with IBK treated by systemic tulathromycin, and subconjunctival injection of penicillin and dexamethasone. We investigated changes in the hematological indices and microorganisms related to IBK after treatment. Neutrophils and monocytes decreased during recovery, so it was assumed that these two types of white cells are associated with IBK. Moraxella bovoculi was cleared in the eye, nasal cavity, and oral cavity after treatment. The distribution of M. bovoculi before treatment indicated that a combined systemic and subconjunctival treatment was necessary. The lesioned eye was found to be overwhelmed by Mycoplasma bovoculi, while pathogen abundance was reduced in the nasal cavity and oral cavities. These results suggest that antibiotic treatment can alter the composition and relative abundance of microorganisms.

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참고문헌

  1. Alexander D. 2010. Infectious bovine keratoconjunctivitis: a review of cases in clinical practice. pp. 487-503. Veterinary Clinics: Food Animal Practice. Elsevier, Philadelphia, PA
  2. Angelos JA, Ball LM, Hess JF. 2007. Identification and characterization of complete RTX operons in Moraxella bovoculi and Moraxella ovis. Vet Microbiol 125: 73-79. https://doi.org/10.1016/j.vetmic.2007.05.009
  3. Angelos JA. 2015. Infectious bovine keratoconjunctivitis (pinkeye). pp. 61-79. Veterinary Clinics: Food Animal Practice. Elsevier, Philadelphia, PA
  4. Arends J, Wright R, Barto P, Lusby K. 1984. Transmission of Moraxella bovis from blood agar cultures to Hereford cattle by face flies (Diptera: Muscidae). J Econ Enotomol 77: 394-398. https://doi.org/10.1093/jee/77.2.394
  5. Beard MM, Moore L. 1994. Reproduction of bovine keratoconjunctivitis with a purified haemolytic and cytotoxic fraction of Moraxella bovis. Vet Microbiol 42: 15-33. https://doi.org/10.1016/0378-1135(94)90074-4
  6. Boileau M, Giedt EJ, Lalman D, Whitworth B. 2015. Pinkeye. Oklahoma Cooperative Extension Service VTMD-9128. pp. 1-4.
  7. Cullen J, Yuan C, Totton S, Dzikamunhenga R, Coetzee J, da Silva N, Wang C, O'Connor A. 2016. A systematic review and meta-analysis of the antibiotic treatment for infectious bovine keratoconjunctivitis: an update. Anim Health Res Rev 17: 60-75. https://doi.org/10.1017/S1466252316000050
  8. Frisch J. 1975. The relative incidence and effect of bovine infectious keratoconjunctivitis in Bos indicus and Bos taurus cattle. Anim Sci 21: 265-274. https://doi.org/10.1017/S0003356100030737
  9. Funk L, O'Connor A, Maroney M, Engelken T, Cooper V, Kinyon J, Plummer P. 2009. A randomized and blinded field trial to assess the efficacy of an autogenous vaccine to prevent naturally occurring infectious bovine keratoconjunctivis (IBK) in beef calves. Vaccine 27: 4585-4590. https://doi.org/10.1016/j.vaccine.2009.05.082
  10. George L, Ardans A, Mihalyi J, Guerra M. 1988. Enhancement of infectious bovine keratoconjunctivitis by modifiedlive infectious bovine rhinotracheitis virus vaccine. Am J Vet Res 49: 1800-1806.
  11. Glass Jr H, Gerhardt R, Greene W. 1982. Survival of Moraxella bovis in the alimentary tract of the face fly. J Econ Enotomol 75: 545-546. https://doi.org/10.1093/jee/75.3.545
  12. Hughes D, Pugh JG, McDonald T. 1965. Ultraviolet radiation and Moraxella bovis in the etiology of bovine infectious keratoconjunctivitis. Am J Vet Res 26: 1331-1338.
  13. Kagonyera G, George L, Munn R. 1989. Cytopathic effects of Moraxella bovis on cultured bovine neutrophils and corneal epithelial cells. Am J Vet Res 50: 10-17.
  14. Lasisi O, Akinbobola J. 2016. Lymphocytopenia in a Calf with Infectious Bovine Keratoconjunctivitis: A Case Report. J Anim Vet Adv 8: 21-24. https://doi.org/10.19026/ijava.8.2694
  15. Lepper A, Barton I. 1987. Infectious bovine keratoconjunctivitis: seasonal variation in cultural, biochemical and immunoreactive properties of Moraxella bovis isolated from the eyes of cattle. Aust Vet J 64: 33-39. https://doi.org/10.1111/j.1751-0813.1987.tb16125.x
  16. Maggs DJ, Miller PE, Ofri R, Slatter DH. 2013. Ocular Pharmacology and Therapeutics. pp. 27-59. 5th ed. Elsevier, St. Louis, MO.
  17. Pugh G, Hughes D, Schulz V. 1976. Infectious bovine keratoconjunctivitis: experimental induction of infection in calves with mycoplasmas and Moraxella bovis. Am J Vet Res 37: 493-495.
  18. Pugh Jr GW, Hughes DE, Packer R. 1970. Bovine infectious keratoconjuncti-vitis: interactions of Moraxella bovis and infectious bovine rhinotracheitis virus. Am J Vet Res 31: 653-662.
  19. Pugh Jr GW, Hughes DE. 1968. Experimental bovine infectious keratoconjunctivitis caused by sunlamp irradiation and Moraxella bovis infection: correlation of hamolytic ability and pathogenicity. Am J Vet Res 29: 835.
  20. Rosenbusch R. 1983. Influence of mycoplasma preinfection on the expression of Moraxella bovis pathogenicity [Infectious bovine keratoconjunctivitis]. Am J Vet Res 44: 1621-1624.
  21. Schnee C, Heller M, Schubert E, Sachse K. 2015. Point prevalence of infection with Mycoplasma bovoculi and Moraxella spp. in cattle at different stages of infectious bovine keratoconjunctivitis. Vet J 203: 92-96. https://doi.org/10.1016/j.tvjl.2014.11.009
  22. Snowder G, Van Vleck LD, Cundiff L, Bennett G. 2005. Genetic and environmental factors associated with incidence of infectious bovine keratoconjunctivitis in preweaned beef calves. J Anim Sci 83: 507-518. https://doi.org/10.2527/2005.833507x
  23. Steve P, Lilly J. 1965. Investigations on transmissability of Moraxella bovis by the face fly. J Econ Enotomol 58: 444-446. https://doi.org/10.1093/jee/58.3.444
  24. Ward J, Nielson M. 1979. Pinkeye (bovine infectious keratoconjunctivitis) in beef cattle. J Anim Sci 49: 361-366. https://doi.org/10.2527/jas1979.492361x
  25. Webber J, Selby L. 1981. Risk factors related to the prevalence of infectious bovine keratoconjunctivitis. J Am Vet Med A 179: 823-826.
  26. Wilcox G. 1968. Infectious bovine keratoconjunctivitis: a review. Vet Bull 38: 349-359.