Journal of Korean Clinical Health Science (한국임상보건과학회지)

The Korean Society of Clinical Health Science (한국임상보건과학회)
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Differences in the expression rate and genotype of Porphyromonas gingivalis according to smoking status

흡연행태에 따른 Porphyromonas gingivalis의 발현율과 유전형 차이

  • 김진경 (대구보건대학교 치위생과)
  • Received : 2020.10.22
  • Accepted : 2020.11.18
  • Published : 2020.12.31
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Abstract

Purpose: The purpose of this study was to differences in the expression rate of Porphyromonas gingivalis according to smoking status, smoking amount and period of smoking. Methods: At the time of investigation, 30 smokers and non-smokers were recruited among patients with periodontitis with a probing pocket depth(PPD) of 4 mm or more. General information was collected using a self-questionnaire, and the average value was used by a dentist to measure the probing pocket depth of three times each for the first or second molar. Plaque collection and analysis were performed by collecting only subgingival plaque using a conventional method, and the expression rate of P. gingivalis was confirmed using polymerase chain reaction (PCR). For statistical analysis, the SPSS Ver 25.0 program was used. Results: Smoking did not have a significant effect on the expression of P. gingivalis, but it did affect the expression of more type II genotypes (p<0.05). In addition, smokers had more slight periodontal pocket, and the amount and duration of smoking did not affect the expression of P. gingivalis. Conclusions: In the future, it is necessary to reinforce the group of smokers and non-smokers with healthy oral conditions, and to investigate the quantitative difference in the expression rate and genotype of P. gingivalis over time of harmful substances in smoking.

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References

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