References
- Hadjidakis DJ, Androulakis, II: Bone remodeling. Ann N Y Acad Sci 1092: 385-396, 2006. https://doi.org/10.1196/annals.1365.035
- Crockett JC, Rogers MJ. et al. Bone remodelling at a glance. J Cell Sci 124: 991-998, 2011. https://doi.org/10.1242/jcs.063032
- Chen X, Wang Z, et al. Osteoblast-osteoclast interactions. Connect Tissue Res 59: 99-107, 2018. https://doi.org/10.1080/03008207.2017.1290085
- Anagnostis P, Stevenson JC. Bisphosphonate drug holidays--when, why and for how long? Climacteric 18 Suppl 2: 32-38, 2015. https://doi.org/10.3109/13697137.2015.1099092
- Lamy O, Stoll D, et al. Stopping Denosumab. Curr Osteoporos Rep 17: 8-15, 2019. https://doi.org/10.1007/s11914-019-00502-4
- Aspenberg P. Denosumab and atypical femoral fractures. Acta Orthop 85: 1, 2014. https://doi.org/10.3109/17453674.2013.859423
- Park YS. Diagnosis and treatment of osteoporosis. J Korean Med Assoc 55: 1083-1094, 2012. https://doi.org/10.5124/jkma.2012.55.11.1083
- Anesi A, Generali L, et al. From Osteoclast Differentiation to Osteonecrosis of the Jaw: Molecular and Clinical Insights. Int J Mol Sci 20, 2019. https://doi.org/10.3390/ijms20194925
- Ono T, Nakashima T. Recent advances in osteoclast biology. Histochem Cell Biol 149: 325-341, 2018. https://doi.org/10.1007/s00418-018-1636-2
- Ikeda K, Takeshita S. The role of osteoclast differentiation and function in skeletal homeostasis. J Biochem 159: 1-8, 2016. https://doi.org/10.1093/jb/mvv112
- Kim JM, Lin C, et al. Osteoblast-Osteoclast Communication and Bone Homeostasis. Cells 9, 2020. https://doi.org/10.3390/cells9092073
- Long F. Building strong bones: molecular regulation of the osteoblast lineage. Nat Rev Mol Cell Biol 13: 27-38, 2011. https://doi.org/10.1038/nrm3254
- Mundy GR. Regulation of bone formation by bone morphogenetic proteins and other growth factors. Clin Orthop Relat Res: 24-28, 1996. https://doi.org/10.1097/00003086-199603000-00004
- Filvaroff E, Erlebacher A, et al.: Inhibition of TGF-beta receptor signaling in osteoblasts leads to decreased bone remodeling and increased trabecular bone mass. Development 126: 4267-4279, 1999 https://doi.org/10.1242/dev.126.19.4267
- Alliston T, Choy L, et al. TGF-beta-induced repression of CBFA1 by Smad3 decreases cbfa1 and osteocalcin expression and inhibits osteoblast differentiation. Embo j 20: 2254-2272, 2001. https://doi.org/10.1093/emboj/20.9.2254
- Fuller K, Lean JM, et al. A role for TGFbeta(1) in osteoclast differentiation and survival. J Cell Sci 113 ( Pt 13): 2445-2453, 2000 https://doi.org/10.1242/jcs.113.13.2445
- Quinn JM, Itoh K, et al. Transforming growth factor beta affects osteoclast differentiation via direct and indirect actions. J Bone Miner Res 16: 1787-1794, 2001. https://doi.org/10.1359/jbmr.2001.16.10.1787
- Lee B, Oh Y, et al. A dual role of TGF-β in human osteoclast differentiation mediated by Smad1 versus Smad3 signaling. Immunol Lett 206: 33-40, 2019. https://doi.org/10.1016/j.imlet.2018.12.003
- Tominaga K, Suzuki HI. TGF-β Signaling in Cellular Senescence and Aging-Related Pathology. Int J Mol Sci 20, 2019. https://doi.org/10.3390/ijms20205002
- Ashraf S, Cha BH, et al. Regulation of senescence associated signaling mechanisms in chondrocytes for cartilage tissue regeneration. Osteoarthritis Cartilage 24: 196-205, 2016. https://doi.org/10.1016/j.joca.2015.07.008
- Cheng Q, Tang W, et al.: Circulating TGF-β1 levels are negatively correlated with sclerostin levels in early postmenopausal women. Clin Chim Acta 455: 87-92, 2016. https://doi.org/10.1016/j.cca.2016.01.025
- Tang SY, Alliston T. Regulation of postnatal bone homeostasis by TGFβ. Bonekey Rep 2: 255, 2013. https://doi.org/10.1038/bonekey.2012.255
- Erlebacher A, Derynck R. Increased expression of TGF-beta 2 in osteoblasts results in an osteoporosis-like phenotype. J Cell Biol 132: 195-210, 1996. https://doi.org/10.1083/jcb.132.1.195
- van der Kraan PM. The changing role of TGFβ in healthy, ageing and osteoarthritic joints. Nat Rev Rheumatol 13: 155-163, 2017. https://doi.org/10.1038/nrrheum.2016.219
- Khosla S. Minireview: the OPG/RANKL/RANK system. Endocrinology 142: 5050-5055, 2001. https://doi.org/10.1210/endo.142.12.8536
- Yasuda H, Shima N, et al.: Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. Proc Natl Acad Sci U S A 95: 3597-3602, 1998. https://doi.org/10.1073/pnas.95.7.3597
- Walsh MC, Choi Y. Biology of the RANKL-RANK-OPG System in Immunity, Bone, and Beyond. Front Immunol 5: 511, 2014. https://doi.org/10.3389/fimmu.2014.00511
- Boyce BF, Xing L. Biology of RANK, RANKL, and osteoprotegerin. Arthritis Res Ther 9 Suppl 1: S1, 2007. https://doi.org/10.1186/ar2165
- Boyce BF, Xing L. Functions of RANKL/RANK/OPG in bone modeling and remodeling. Arch Biochem Biophys 473: 139-146, 2008. https://doi.org/10.1016/j.abb.2008.03.018
- Yasuda H, Shima N, et al.: Identity of osteoclastogenesis inhibitory factor (OCIF) and osteoprotegerin (OPG): a mechanism by which OPG/OCIF inhibits osteoclastogenesis in vitro. Endocrinology 139: 1329-1337, 1998. https://doi.org/10.1210/endo.139.3.5837
- Simonet WS, Lacey DL, et al.: Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. Cell 89: 309-319, 1997. https://doi.org/10.1016/s0092-8674(00)80209-3
- Lacey DL, Tan HL, et al.: Osteoprotegerin ligand modulates murine osteoclast survival in vitro and in vivo. Am J Pathol 157: 435-448, 2000. https://doi.org/10.1016/s0002-9440(10)64556-7
- Tanaka H, Mine T, et al. Expression of RANKL/OPG during bone remodeling in vivo. Biochem Biophys Res Commun 411: 690-694, 2011. https://doi.org/10.1016/j.bbrc.2011.07.001
- Sims NA, Martin TJ. Coupling the activities of bone formation and resorption: a multitude of signals within the basic multicellular unit. Bonekey Rep 3: 481, 2014. https://doi.org/10.1038/bonekey.2013.215
- Kanis JA. Assessment of fracture risk and its application to screening for postmenopausal osteoporosis: synopsis of a WHO report. WHO Study Group. Osteoporos Int 4: 368-381, 1994. https://doi.org/10.1007/bf01622200
- Piscitelli P, Feola M, et al.: Ten years of hip fractures in Italy: For the first time a decreasing trend in elderly women. World J Orthop 5: 386-391, 2014. https://doi.org/10.5312/wjo.v5.i3.386
- Al Anouti F, Taha Z, et al. An insight into the paradigms of osteoporosis: From genetics to biomechanics. Bone Rep 11: 100216, 2019. https://doi.org/10.1016/j.bonr.2019.100216
- Kim Y, Kim JH, et al. [Gender difference in osteoporosis prevalence, awareness and treatment: based on the Korea national health and nutrition examination survey 2008-2011]. J Korean Acad Nurs 45: 293-305, 2015. https://doi.org/10.4040/jkan.2015.45.2.293
- Cremers S, Papapoulos S. Pharmacology of bisphosphonates. Bone 49: 42-49, 2011. https://doi.org/10.1016/j.bone.2011.01.014
- Tanaka S. Molecular understanding of pharmacological treatment of osteoporosis. EFORT Open Rev 4: 158-164, 2019. https://doi.org/10.1302/2058-5241.4.180018
- Fliefel R, Troltzsch M, et al. Treatment strategies and outcomes of bisphosphonate-related osteonecrosis of the jaw (BRONJ) with characterization of patients: a systematic review. Int J Oral Maxillofac Surg 44: 568-585, 2015. https://doi.org/10.1016/j.ijom.2015.01.026
- Han Y-S, Lee I-W, et al. Retrospective study on the bisphosphonate-related osteonecrosis of jaw. Journal of the Korean Association of Oral and Maxillofacial Surgeons 37, 2011. https://doi.org/10.5125/jkaoms.2011.37.6.470
- Patel V, McLeod NM, et al. Bisphosphonate osteonecrosis of the jaw--a literature review of UK policies versus international policies on bisphosphonates, risk factors and prevention. Br J Oral Maxillofac Surg 49: 251-257, 2011. https://doi.org/10.1016/j.bjoms.2010.05.007
- Vescovi P, Nammour S. Bisphosphonate-Related Osteonecrosis of the Jaw (BRONJ) therapy. A critical review. Minerva Stomatol 59: 181-203, 204-113, 2010
- Choi HS. Recent Update on RANKL Inhibitor. Korean J Med 93: 252-259, 2018. https://doi.org/10.3904/kjm.2018.93.3.252
- Roux S, Massicotte MH, et al. Acute hypercalcemia and excessive bone resorption following anti-RANKL withdrawal: Case report and brief literature review. Bone 120: 482-486, 2019. https://doi.org/10.1016/j.bone.2018.12.012